Endocrine Abstracts

Acromegaly is a rare disorder with a high morbidity and mortality rate. The diagnosis is typically prolonged over time due to a slow and hidden development of the disease. Current medical therapy for the treatment of acromegaly involves the administration of somatostatin analogues that effectively suppress excess hormone secretion. The objective of this study was to investigate the efficacy of octreotide therapy in acromegalic. A total of 32 patients have been treated with Oct...

Introduction: Basal ganglia calcification or Fahr’s Syndrome is a rare form of neurological disorder. Its prevalence goes from 2 to 12.5 %. It can be primary (idiopathic) or secondary (from metabolic disorders especially from hypoparathyroidism).We present the case of a female patient with hypoparathyroidism and secondary Fahr’s Disease.Case description: The patient L.J. 61 years old, from Pogradec, Albania, who came to the emergency room wit...

Diabetic ketoacidosis is a well- known and a major acute complication of diabetes, mainly of the patients with type 1 diabetes. It is not uncommon in patients with type 2 diabetes. This situation is characterised by the presence of serum ketones greater than 5 mEq/l and ketonuria, a blood glucose level greater than 250 mg/dl, a blood PH less than 7.3 and a serum bicarbonate level of less than 18 mEq/l. There are different factors that cause ketoacidosis. DKA can be the initial...

Thyrotoxicosis is characterised by the excess of thyroid hormones into blood. The most extreme appearance of it, is thyroid storm which is presented as an acute, severe, life-threatening, hypermetabolic state caused by the added quantities of thyroid hormones, causing adrenergic hyperactivity and abnormal periphery response of thyroid hormones. The incidence of thyroid storm is evaluated at 0.2/100000 in year. The mortality of untreated thyroid storm varies from 80–100% w...

It is well known nowadays the positive effect that early detection of prediabetes has in preventing and postponing the diabetes onset. The aim of our study is to explore the diabetes prevalence in Albania and to identify and stratify the population at risk for developing diabetes.Material and methods: A large scale multicentre screening was performed in Albania as part of a National Campaign. 15744 patients were consecutively recluted. The following data...

Background: The involvement of nurses in diabetes patient education has an important contribution in the improvement in the quality of care provided. Experience and knowledge in diabetes and its management are crucial for teaching patients with diabetes effectively.Material and methods: The aim of the study is to evaluate the effect of nurse Training Course in the improvement of the knowledge of diabetes among nurses. Ten Diabetes Education Unit’s n...

Introduction: A thyroid nodule discovered in a patient with Graves’ disease (GD) should be evaluated and managed according to guidelines. A subcentimetre incidental thyroid cancer founded in a patients with GD, without high-risk history, without suspicious sonographic (US) features has not been reported yet.Clinical case: A 40-year-old female patient, presented to our hospital with symptoms of thyrotoxicosis. On physical examination heart rate was 1...

Introduction: Metformin-associated lactic acidosis (MALA) is defined as a high anion gap metabolic acidosis with high circulating lactate levels and without hypoperfusion. It is associated with a mortality rate up to 50%.The reported frequency is 0.01–0.05/1000 patient-years, mostly in patients with predisposing factors (which affect its clearance or energy metabolism) such as altered renal function, congestive heart, hepatic and respiratory failure, concomitant medicatio...

Introduction: Drug-induced lupus erythematosus (DILE) is a variant of systemic lupus erythematosus that resolves within days to months after withdrawal of the drug, in a patient with no previous history of SLE.Case report: A 60-year-old female presented at Mother Teresa Hospital with toxic multinodular goiter. She received treatment with propylthiouracil and atenolol for a month, and she developed symptoms like malaise, muscle pain, shortness of breath, ...

Introduction: Thrombosis of the portal venous system is rare with the prevalence about 1% in the general population reported previously, difficult to diagnose and can be fatal. We report a case of previously-undiagnosed type 2 diabetes mellitus presenting as portal venous system thrombosis and reviewed the pertinent medical literature.Case presentation: A 54-year-old white female was admitted to our hospital with 10 days history of vague...