Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1243 | Thyroid (non-cancer) | ECE2017

Aggravation of thyroid dysfunction in a case of thyroid hormone resistance after near total thyroidectomy for multinodular goiter

Kartal Ilkay , Tamer Gonca

Introduction: Resistance to thyroid hormone (RTH), a syndrome reduced end-organ responsiveness to thyroid hormone.Case report: A 42 year old woman underwent near total thyroidectomy due to her enlarged thyroid with multiple nodules. At that time she had sligthly elevated values of plasma FT4, FT3 and normal TSH values and had no sign and symptoms of thyrotoxicosis or hypothyroidism. After thyroidectomy she recieved L-T4 treatment but her TSH levels remai...

ea0037ep1182 | Clinical Cases–Pituitary/Adrenal | ECE2015

17 α hydroxylase enzyme deficiency with hyperaldosteronism

Kartal Ilkay , Tamer Gonca Incemehmet , Mutlu Hasan Huseyin

Background: Congenital adrenal hyperplasia (CAH) resulting from 17 α hyroxylase enzyme deficiency (17OHD) is a rare autosomal recessive disorder. More than 150 cases were reported in the literature. Patients with 17OHD were reported to have hypoaldosteronism.Case: A 16-year-old female referred to endocrinology outpatient clinic from family medicine department with the absence of a secondary sexual characteristics and primary amenorrhea. On physical ...

ea0035p917 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Treating prolactinoma by endoscopic endonasal pituitary surgery: surgical experience of 151 cases

Akin Safak , Berker Mustafa , Isikay Ilkay , Gurlek Alper

Background and Aim: Prolactinoma is the most common type of functional pituitary tumor in adults. Giant prolactinomas are defined as tumors achieve a diameter >4 cm and often have very high serum prolactin level. In our previous study showed that endoscopic endonasal pituitary surgery is a very convenient procedure for the patient due to low morbidity and high efficiency. In this study we evaluated endoscopic endonasal pituitary surgery series in patients with prolactinoma...

ea0022p372 | Endocrine Disruptors | ECE2010

Evaluation of paraxonase activity, malondialdehyde and thiol levels in patients with hypogonadism before and after treatment

Bayram Fahri , Baskol Gulden , Demirkoparan Umit , Gundogan Kursad , Cakir Ilkay

Objectives: Hypogonadism is associated with a higher risk of atherosclerosis and cardiovascular disease, but the mechanisms underlying this association are not yet fully understood. Increased oxidative stress has been associated with development of cardiovascular and cerebrovascular diseases. We aimed to determine serum PON1 activities, an established lipid antioxidant, MDA levels which are end products of lipid peroxidation induced by ROS and thiol groups as an antioxidant fo...

ea0022p374 | Endocrine Disruptors | ECE2010

Paraoxonase is reduced in patients with GH deficiency: a risk factor for atherosclerosis?

Bayram Fahri , Baskol Gulden , Tanriverdi Fatih , Kocer Derya , Cakir Ilkay

Objective: GH deficiency is associated with an increased cardiovascular mortality. Increased oxidative stress has been associated with development of cardiovascular and cerebrovascular diseases. In the present study, we aimed to determine i) serum PON1 activities, an established lipid antioxidant, ii) MDA levels which are end products of lipid peroxidation induced by ROS and iii) thiol groups as an antioxidant for evaluating oxidative stress in patients with GHD before and aft...

ea0014p513 | (1) | ECE2007

Diabetes insipidus due to pituitary metastasis of breast cancer

Kubat Uzum Ayse , Kartal Ilkay , Mert Meral , Aral Ferihan

Introduction: We have reported a case of breast carcinoma complicated by diabetes insipidus due to pituitary metastasis.Case: A 47 years old woman had been referred our clinic with the symptoms of polyuria, polydypsia, weight loss, and fatigue. She had a diagnosis of breast carcinoma for six years, underwent radically mastectomy, chemotherapy and radiotherapy, subsequently. Vertebral metastasis was detected and local radiotherapy was performed six months...

ea0099p562 | Reproductive and Developmental Endocrinology | ECE2024

Assessment of muscle mass and strength in women with PCOS following oral contraceptive therapy

Aksun Seren , Karacoban Levend , Idilman Ilkay , Yildiz Bulent

Background and Aim: Polycystic ovary syndrome (PCOS) is characterized by androgen excess and ovulatory dysfunction and appears to be associated with alterations in muscle mass and function. Combined oral contraceptives are commonly used for the long-term management of PCOS and their potential impact on muscle mass and strength remains unknown. This study aimed to assess whether oral contraceptive (OC) use along with general lifestyle advice would alter muscle mass and strength...

ea0063p296 | Pituitary and Neuroendocrinology 1 | ECE2019

A Case of Granulomatous Hypophysitis Mimicking Pituitary Macroadenoma

Dogansen Sema Ciftci , Gunaldi Omur , Tanrıverdi Osman , Cakir Ilkay , Mert Meral

Idiopathic granulomatoushypophysitis is a rare inflammatory disease which is characterized by inflammation and cellular infiltration of the pituitary gland. The infiltration may cause pituitary insufficiency, compression symptoms due to mass effect and diabetes insipidus. We report the case of a 33-year-old female patient who presenting with weakness, fatigue, amenorrhea and worsening of headaches about 3 months. The patient did not have blurring vision and polyuria-polydipsia...

ea0049ep447 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Relationship with T helper 1 cytokines and type 2 diabetes

Gonca Tamer Havva , Caklili Ozge Telci , Kartal Ilkay , Gungor Kagan , Mutlu Hasan Huseyin

Objectives: T helper1 (Th1) cells were determined to have important roles in the development of type 2 diabetes (T2D). We aimed to investigate relationship between Th1 cytokines (IFN γ, IL-2 and TNF-α) and T2D.Material and methods: The study included 32 newly diagnosed type 2 diabetic patients (T2DPs) who had not begun to take antidiabetic agents except from insulin and 30 healthy subjects (CG) who did not have glucose intoerance (fasting or af...

ea0037ep498 | Diabetes (complications &amp; therapy) | ECE2015

Real-time sonoelastography and ultrasound evaluation of Achilles tendon of diabetic patients

Evranos Berna , Idilman Ilkay , Ipek Ali , Polat Sefika Burcak , Cakir Bekir , Ersoy Reyhan

Introduction: Diabetes mellitus (DM) is an endocrine disease characterised by metabolic abnormalities and long-term complications. Achilles tendon (AT) play an important role in foot biomechanics. We aimed to investigate the effect of DM on the AT, which may contribute to the long-term complications in the foot–ankle complex.Materials and methods: 78 diabetic patients with (35 cases) or without (43 cases) diabetic foot ulcers were recruited from End...