Endocrine Abstracts

Introduction: Radioiodine whole-body scintigraphy (WBS) has been widely used for detection of differentiated thyroid cancer (DTC), based on the marked storage of iodine in functioning thyroid tissue. However, radioiodine uptake is not specific for thyroid gland. Iodine accumulation in lactating breast has been demonstrated, but it is rare in nonlactating breast.Case report: A 74-year-old-woman who underwent near-total thyroidectomy in 1988 due to a multi...

Incidental thyroid carcinoma includes thyroid carcinomas detected after surgery in patients whose thyroid has been correctly studied with no data of malignancy. Lately, the widely spread use of image techniques and thorough search of thyroid nodule complains, have lead to a growing number of thyroid carcinomas. But still there are some of these incidentally discovered after thyroidectomy.We report 98 cases of thyroid carcinomas incidentally found from a ...

Current treatment for acromegaly includes dopamine agonists (DA), somatostatin receptor ligands (SRL) and GH receptor antagonists (GHRA). DA in monotherapy, is less than 10% effective achieving control of the disease, and its efficacy in addition to ongoing SRL is less studied, without obvious determining factors of response. We report 2 operated patients with incomplete response to SRL and to whom Cabergoline addition led to disease control.Case 1: A ma...

Autoimmune polyendocrinopathy syndromes (APS) gather a wide range of diseases. The association of autoimmune thyroid disease (ATD) with other organ specific diseases is frequent. Atrophic body gastritis (ABP) is characterized by the loss of ClH and intrinsic factor (IF) production. Both ATD and ABP are known to be associated since 1960 but there are scarce publications describing its clinical features.We review patients with this association selected fro...

Surgery followed by 131I ablative therapy (IAT) is the usual treatment for patients with differentiated thyroid carcinoma (DTC). Thyroglobulin levels obtained 9–12 months after IAT under TSH stimulation (Tg2) is a very reliable marker for the presence of thyroid tissue. The value of stimulated thyroglobulin previous to ablation (Tg1) is more controversial. The aim of this study was to examine the relationship between Tg1 and Tg2.Material ...

Background and aims: Transition of patients with type 1 diabetes (DM1) from pediatric to adult care is challenging and international guidelines recommend effective transition programs. The aim of this study is to describe our baseline situation, without a structured transition program, and to identify factors associated with worse glycemic outcome.Materials and Methods: This is an observational, retrospective study of patients with DM1, aged 14 or more o...

Fine-needle aspiration cytology (FNAC) remains the mainstay in the study of thyroid nodules, with cytologic adequate specimens in almost 85% of cases in expert hands. Apart from the limitation of inadequate samples, there are false negative diagnoses in some cases, particularly in larger (>3 cm) nodules. Considering this, Large-needle biopsy (LNB) could be useful to improve diagnostic precision. We review the pathology reports (PR) of more than 100 patients operated since ...

IntroductionParathyromatosis is a potential cause of recurrent hyperparathyroidism, of rare etiology, described as multiple nodules of hyperfunctioning benign parathyroid tissue, it constitutes less than 1% of the cases of recurrent hyperparathyroidism and since its description in 1975, less than 40 cases have been reported Worldwide. The presentation in primary hyperparathyroidism is extremely rare, with around 20 cases reported in the English literatur...

Introduction and objectivesSGT2i have changed the paradigm of T2DM management. Last guidelines insist on the importance of using newer glucose-lowering drugs with a demonstrated reduction in cardiovascular events (CVE). The aim of this study is twofold: to describe CVE, heart failure (HF) and renal function evolution; and to assess its efficacy in non-selected patients with T2DM initiating SGLT2iMaterial and methods<p class="ab...