Endocrine Abstracts

IntroductionPatients with primary adrenal insufficiency (PAI) may have musculoskeletal symptoms. However, the association of such endocrinopathy with scleromyositis is extremely rare and has not been reported formerly to our acknowledge. Herein we report this association.Case reportA 32-years old female with one year history of profound global weakness was referred to internal department in April 2006, for su...

IntroductionThe ectopic parathyroid adenoma (EPTA) is the most common cause of failed parathyroid surgery. Most often localisations are intra-thymic and intra-mediastinal adenomas. We report a rare presentation of a symptomatic parathyroid adenoma located in ectopic retropharyngeal position diagnosed after surgical treatment of primary hyperparathyroidism (PHPT).ObsevationA 42-year-old female was referred to ...

IntroductionHypopituitarism is a rare condition defined by loss of pituitary function due to involvement of hypothalamus and/or pituitary gland by infiltrative diseases mainly sarcoidosis and Langerhans cell histiocytosis (LCH). Central diabetes insipidus is the most frequent manifestation of LCH (10–50%) and rarely in neuro-sarcoidois. Herein, we describe 2cases of hypopituitarism due to neuro-sarcoidosis and LCH.Case 1<p...

Introduction: Type 1 diabetes mellitus (T1DM) is the result of the autoimmune destruction of beta-cells of the endocrine pancreas, leading to absolute insulin deficiency. The process of this autoimmune destruction occurs in genetically susceptible individuals with positive relevant autoantibodies. T1DM may be associated with other autoimmune diseases (AD) such as autoimmune thyroid disorders (AITD). Patients and methods: It is a descriptive retrospective...

Introduction: Hypothyroidism is a consequence of thyroid hormone deficiency which may be of peripheral or central origin. If hypothyroidism is left untreated, the symptoms progress and lead to life-threatening complications.Patients and method: Retrospective study of 67 patients with primary hypothyroidism. We determined the different complications associated with hypothyroidism.Results: We collected 67 patients with overt hypothyr...

Introduction: Autoimmune bullous dermatoses (ABD) represent a heterogeneous group of AIDs that target different epidermal or subepidermal proteins of the skin and/or mucous membranes. As with any autoimmune disease (AID), it may be associated with other AIDs. We report a case of ABD associated with Graves’ disease (GD).Observation: The ABD was a pemphigus vulgaris (PV) that was diagnosed at the age of 25 years in our patient and she was treated with...

Introduction: Myasthenia gravis (MG) is a chronic neuromuscular condition characterized by weakness in voluntary muscles. It is an autoimmune disorder. The emergence of the condition can be abrupt. As with any autoimmune disease (AID), it may be associated with other AIDs. We report a case of MG associated with Hashimoto’s thyroiditis (HT).Observation: The diagnosis of MG was established in a 58-year-old patient, based on the progressive onset of fa...

Introduction: Despite being organ-specific autoimmune diseases (AID), autoimmune thyroid diseases (AITD) may be associated with other AIDs either specific to other organs or systemic. These associations are not uncommon. They may be grouped in the form of an autoimmune polyendocrinopathy or multiple autoimmune syndrome (MAS). MAS is defined by the presence in the same person of at least three AIDs.Patients and Methods: It is a retrospective study over a ...

Introduction: Overt hyperthyroidism is the result of excessive production of thyroid hormones. The diagnosis is made on the basis of clinical characteristics and the diagnosis of certainty is made by hormone assay, combining low TSH with increased thyroid hormones. If the hyperthyroidism is left untreated, symptoms progress and can lead to complications that may jeopardize life prognosis.Patients and Methods: A retrospective study involving 29 patients w...

Introduction: Graves’ disease (GD), an autoimmune disorder predominantly impacting the thyroid gland, can extend its effects to various organs, such as the eyes and skin. It stands as the leading cause of hyperthyroidism. It is defined by the pathognomonic combination of thyrotoxicosis, goitre and exophthalmos. The aim of this study was to identify the characteristics of GD.Patients and Methods: A retrospective study involving 31 patients with prima...