Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep476 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Can Alopecia Areata predict the appearance of autoimmune diabetes in a patient with autoimmune polyglandular syndrome type 2?

Corlan Ana Silvia , Vlad Mihaela

Autoimmune polyglandular syndrome type 2 can be associated with alopecia areata. We present herein a case of a female patient, 42 years old, who suffered from autoimmune thyroid disease with hypothyroidism and autoimmune adrenalitis and who was recently diagnosed with alopecia areata. She accused sudden, asymptomatic hair loss, which she noticed 3 months ago, accompanied by a burning sensation in her scalp. Her menstrual cycles were normal. The clinical examination identified ...

ea0022p211 | Clinical case reports and clinical practice | ECE2010

Unilateral Graves' orbitopathy and autoimmune atrophic thyroiditis: case report

Vlad Mihaela , Golu Ioana , Zosin Ioana

Graves’ orbitopathy (GO) represents ophthalmic symptoms that affect, usually, patients with Graves’ disease. Rarely, it can occur in subjects without thyroid dysfunction or with hypothyroidism (2–5% of the cases).In this report we present a rare case with unilateral GO and initial euthyroidism, which progressed to hypothyroidism, due to an autoimmune atrophic thyroiditis.A 39-year-old woman, long-term smoker, was ref...

ea0073aep702 | Thyroid | ECE2021

Management of Graves’s disease during pregnancy in Covid-19 pandemic conditions - case presentation

Hassan Mervat , Golu Ioana , Vlad Mihaela

IntroductionThe global pandemic caused by the SarsCov2 virus has brought great challenges to the medical system, the management of some cases, especially for those belonging to risk categories, such as pregnant women, being often difficult in this context. Telemedicine has been used frequently during this period, facilitating reducing patient’s risk for exposure to COVID-19, providing continuous support, and coordinating the necessary services to pr...

ea0063p1102 | Pituitary and Neuroendocrinology 3 | ECE2019

The significance of low TSH value – case report

Vlad Mihaela , Amzar Daniela , Sotanga Lavinia , Toma Andreea

Introduction: Suppression of TSH usually indicates hyperthyroidism. But the etiology of low TSH is very wide, including pituitary pathology. In this report we describe a case diagnosed and treated for hyperthyroidism. Later on, the persistence of suppressed TSH after therapy of hyperthyroidism was due to a GH-secreting pituitary adenoma.Case presentation: A 47-year old woman was referred to our clinic for investigations, due to thyroid pathology. The pat...

ea0049ep153 | Endocrine tumours and neoplasia | ECE2017

Primary hepatic neuroendocrine tumor with multiple liver metastases treated with somatostatin analogues: case report

Golu Ioana , Balas Melania , Amzar Daniela , Cornianu Marioara , Vlad Mihaela

Introduction: Somatostatin analogues (SSA) have been used as first line treatment to control the symtoms in hormonally active neuroendocrine tumors (NET), for over three decades. Primary hepatic neuroendocrine tumors (PHNETs) are rare neoplasms. Despite increased incidence of PHNETs over time, these tumors remain a rarity. According to the previously reported cases, primary neuroendocrine carcinoma of the liver is usually multicentric, often mimicking liver metastases. The dem...

ea0035p893 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Post-partum pituitary insufficiency: diagnostic challenge

Amzar Daniela , Balas Melania , Golu Ioana , Vlad Mihaela , Zosin Ioana

Background: Postpartum hypopituitarism, known as Sheehan’s syndrome, occurs during a complicated childbirth, due to severe hemorrhage and hpovolemic shock that lead to ischemic necrosis of the pituitary gland.The aim of the study is to point out the clinical features in postpartum pituitary necrosis, so that the disease could be recognize rapidly, to present a laboratory work-up for a postive diagnosis, and also to describe the com...

ea0035p1016 | Thyroid (non-cancer) | ECE2014

Different therapeutic outcomes in two cases with active moderate-to-severe Graves'orbitopathy treated with intravenous steroid therapy-case presentation

Zosin Ioana , Vlad Mihaela , Balas Melania , Bolintineanu Carmen

Background: Graves’ orbitopathy (GO) comprises mild, moderate-to-severe and severe forms. The treatment is complex, depending on the activity and severity of the disease. Patients with active moderate-to-severe GO benefit by correction of thyrotoxicosis and glucocorticoids (GC), as first-line agents. Approximately 20-40% of cases are not responsive to GC therapy.Case presentations: There are presented two cases with active moderate-to-severe GO trea...

ea0032p1047 | Thyroid (non-cancer) | ECE2013

Clinical and subclinical hypothyroidism and their relation to cardiovascular risk factors

Golu Ioana , Vlad Mihaela , Cornianu Marioara , Amzar Dana , Tudoran Cristina

The cardiovascular system (CVS) is one of the major targets of thyroid hormone action.The thyroid function has a direct effect on heart rate, cardiac output and systemic vascular resistance.The prevalence of hypothyroidism in the general population is high, particularly in females (9–15%). Overt hypothyroidism is associated with severe cardiovascular manifestations including reduced intravascular volume, increased systemic vas...

ea0026p293 | Pituitary | ECE2011

Prevalence of sleep apnea sindrome (SAS) in patients with acromegaly

Amzar Daniela , Mihaicuta Stefan , Golu Ioana , Balas Melania , Vlad Mihaela

Sleep apnea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the disease. Consequences of SAS are serious and are associated with increased morbidity and mortality.The present study evaluates clinical aspects in acromegalic patients with sleep apnea syndrome (SAS), diagnosed and followed-up in the Clinic of Endocrinology, Timisoara, in the period 2007–2010. All the cases were confirmed and investi...

ea0056p248 | Calcium &amp; Vitamin D metabolism | ECE2018

Recurrent hyperparathyroidism: parathyroid carcinoma or parathyromatosis?

Alina Isaic , Flore Varcus , Maria Cornianu , Ioana Golu , Mihaela Vlad

Recurrent hyperparathyroidism (HPT) refers to reappearance of hypercalcemia after a normocalcemic period of at least 6 months post-parathyroidectomy. Parathyroid carcinoma is a rare cause of primary hyperparathyroidism (pHPT), accounting for 0.4–5.2% of cases. Parathyromatosis is defined as small nodules of hyperfunctioning parathyroid tissue scattered in the soft tissues of the neck and/or mediastinum. We describe two cases with recurrent hypercalcemia after surgical int...