Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep704 | Pituitary and Neuroendocrinology | ECE2022

Cessation of GH secretion in acromegaly without medical or surgical intervetion; Covid-postponed surgery was escaped

Erdei Annamaria , Daniel Eszter , Gazdag Annamaria , Griger Miha ly , Nagy Edit B , Nagy Endre V

Introduction: Acromegaly is usually caused by pituitary macroadenoma producing excess growth hormone. Treatment options include surgery to remove the tumor, medications, and radiation therapy.Case report: A 39-year-old woman has been referred to the endocrine clinic with suspected acromegaly in December 2019. Surgery for benign ovarian cyst, endometriosis, amenorrhoea, unsuccessful in vitro fertilisations were present in her medical history. She complain...

ea0084op-02-07 | Oral Session 2: Pregnancy | ETA2022

Use of levothyroxine for euthyroid women with positive thyroid antibodies and infertility: Results of thesis (treatment of hypothyroidism in europe by specialists: an international survey)

Negro Roberto , Hegedus Laszlo , Attanasio Roberto , Nagy Endre V. , Papini Enrico , Zarkovic Milos , Perros Petros

Objectives: The use of levothyroxine (LT4) treatment aiming to improve fertility in euthyroid women with positive thyroid peroxidase antibodies (TPOAb), is not supported by the available evidence, however the extent to which this is applied in clinical practice is unknown. The aim of the study was to document the demographic, work-related characteristics, and therapeutic choices of European physicians in the case of euthyroid infertile women positive for TPOAb.<p class="ab...

ea0014p358 | (1) | ECE2007

Water purification technology reduces iodine content of drinking water and contributes to iodine deficiency

Samson Laszlo , Czegeny Ildiko , Nagy Endre V , Mezosi Emese , Erdei Annamaria

Drinking water is the major natural source of iodine in many European countries. In the present study, we examined possible sites of iodine loss during the usual water purification process. Water samples from 6 sites during the technological process were taken and analyzed for iodine content. Under laboratory circumstances, prepared iodine in water solution has been used as a model to test the effect of the presence of chlorine. Samples from the purification sites revealed tha...

ea0081ep961 | Thyroid | ECE2022

Use of thyroid hormone in hypothyroid and euthyroid patients. the THESIS questionnaire survey in spain

Carlos Galofre Juan , Attanasio Roberto , Hegedus Laszlo , Nagy Endre V. , Negro Roberto , Papini Enrico , Perros Petros , Diez Juan Jose

Background: Hypothyroidism is one of the most frequent conditions in endocrinology. Despite of that fact, indications for treatment differ among specialists in Spain.Aims: To identify attitudes of Spanish endocrinologists in the use of levothyroxine (LT4) therapy and the management of hypothyroidism.Methods: The members of the Sociedad Española de Endocrinología y Nutrición (Spanish Society of Endocrinology ...

ea0063p719 | Pituitary and Neuroendocrinology 2 | ECE2019

Control of hyperglycemia in a young male patient with gigantism during transition: a case report

Berta Eszter , Lengyel Inez Mercedesz , Halmi Sandor , Puskas Istvan , Felszeghy Enikő , Balogh Zoltan , Nagy Endre V , Bodor Miklos

Introduction: In acromegaly GH excess leads to impaired insulin sensitivity with an alteration of beta-cell function. The consequent hyperglycemia leads to a further increased cardiovascular risk and mortality.Case report: A 16 years old patient was first referred to the Department of Pediatrics in 2014 with accentuated growth since the age of 10. The reason of the first referral was a sport injury (head trauma during playing basketball). Sella MRI depic...

ea0063p781 | Thyroid 2 | ECE2019

Iodine and selenium status in adult PKU

Sumanszki Csaba , Kiss Erika , Simon Erika , Galgoczi Erika , Soos Aron , Patocs Attila , Kovacs Bela , Nagy Endre V , Reismann Peter

Background: The standard, lifelong therapy of phenylketonuria (PKU) is natural protein-restricted diet completed with Phenylalanine (Phe)-free L-amino acid mixtures that provide the daily necessary micronutrients, such as iodine and selenium. Our main objective in this study was to assess the iodine and selenium status of patients with PKU, based on their adherence to the low-Phe diet, compared to a healthy control group. Secondly, we aimed to asses whether adherence to therap...

ea0070ep364 | Pituitary and Neuroendocrinology | ECE2020

Insulinoma localized by Ca-stimulation angiography: A case report

Halmi Sándor , Berta Eszter , Erdei Annamária , Lengyel Inez , Nagy Endre V. , Bodor Miklós

Introduction: Insulinoma is a rare tumor of the beta cells of the pancreas. The clinical manifestation is diverse with hypoglycemia and autonomic neurological symptoms. For diagnosis the Whipple’s triad needs to be present: signs of hypoglycemia, glucose level under 3 mmol/l and the cessation of symptoms after administration of iv. glucose. The fasting test confirms the diagnosis. The most commonly used imaging techniques that may localize the tumor are the abdominal ult...

ea0014p135 | (1) | ECE2007

Papillary thyroid cancer – the possible role of death ligands in tumor immunology

Mezosi Emese , Gyory Ferenc , Borbely Agnes , Ujhelyi Bernadett , Soos Gyorgyike , Nagy Endre V. , Varga Zsuzsa , Bajnok Laszlo

Papillary thyroid cancer (PTC) cells and immune cells can kill each other by death ligands. Death ligands induce apoptosis only in sensitive cells. The sensitivity to apoptosis is regulated in a complex and poorly understood manner. The aim of this study was to investigate the Fas ligand (FasL) and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) expression in PTC cells and tumor infiltrating immune cells. Twenty-six PTCs without and fifteen PTCs with cervical l...

ea0056p1095 | Thyroid (non-cancer) | ECE2018

Serum chemerin and other dyslipidemia markers in patients with autoimmune thyroiditis

Berta Eszter , Harangi Mariann , Varga Viktoria E , Lorincz Hajnalka , Seres Ildiko , Halmi Sandor , Nagy Endre V , Paragh Gyorgy , Bodor Miklos

Aim: Chemerin, a recently discovered adipokine produced by the adipose tissue and liver, along with other atherosclerosis markers, was associated lately with metabolic syndrome and acts as chemoattractant for immune cells may also regulate immune cell properties. Autoimmune Hashimoto’s thyroiditis even with sTSH levels corrected to be within the normal range values may be accompanied by dyslipidemia presenting increased total-C, TG, LDL-C, and Lp(a), all of which are pote...

ea0092ps3-21-01 | Hypothyroidism | ETA2023

Patients’ persistent symptoms during therapy for hypothyroidism: results from the "thesis"* collaboration. (*treatment of hypothyroidism in europe by specialists, an international survey)

Attanasio Roberto , Zarkovic Milos , Hegedus Laszlo , Nagy Endre V. , Negro Roberto , Perros Petros , Papini Enrico , on behalf of the THESIS collaborators group

Background: Levothyroxine (LT4) is considered the standard of care for hypothyroidism, however 5-10% of hypothyroid individuals complain of persistent symptoms despite achieving biochemical euthyroidism on LT4.Methods: 17,247 thyroid specialists from 28 countries were invited to participate in a survey. It enquired about respondents’ perceptions of the cause of hypothyroid-like persistent symptoms and how the prevalence of such complaints had change...