Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1261 | Thyroid (non-cancer) | ECE2017

Therapeutic options in severe thyrotoxicosis with malabsorption

Stojkovic Mirjana , Savic Slavica , Nedeljkovic-Beleslin Biljana , Ciric Jasmina , Nisic Tanja , Zarkovic Milos

Abstract: A 55-year-old woman was admitted to our hospital due to severe hyperthyreosis. She started to feel symptoms of hyper-metabolism four months prior to hospitalization. At that time she was admitted in regional hospital and had gastroenterological examination because of diarrhea. Crohn’s disease was diagnosed and therapy started. At the same time, thyrosupressive therapy started. She had a history of hyperthyreosis thirteen years ago, duodenal hemorrhage ulcer, hyp...

ea0016p24 | Adrenal | ECE2008

Association of diabetes mellitus and arterial hypertension in adrenal incidentaloma

Zarkovic Milos , Ciric Jasmina , Beleslin Biljana , Savic Slavica , Stojkovic Mirjana , Marina Djordje , Trbojevic Bozo

Background/objectives: The aim of the study was to assess association between diabetes mellitus (DM) and arterial hypertension (AH) in patients with adrenal incidentaloma.Design and methods: One hundred and eleven consecutive patients with incidentally discovered adrenal tumours were included in the study. OGTT was done and 24 h urinary catecholamines were measured. Aldosterone and plasma renine activity (PRA) were determined, and 1 mg dexametasone test ...

ea0016p619 | Reproduction | ECE2008

Intima-media tickness of carotid artery in young women with polycystic ovary syndrome

Stojkovic Mirjana , Civcic Milorad , Beleslin Biljana , Ciric Jasmina , Savic Slavica , Marina Djordje , Trbojevic Bozo , Zarkovic Milos

Background: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disease that occurs in about 10% of women in reproductive age. Today, PCOS is considered not only reproductive edocrinopathy but also a metabolic disorder associated with long-term health risks, including diabetes mellitus and cardiovascular disease.Objectives: The aim of this study was to evaluate the presense of early vascular demage in normal-weight women with polycystic ovar...

ea0016p732 | Thyroid | ECE2008

Correlations between lipids and thyroid hormones in primary hypothyroidism

Savic Slavica , Trbojevic Bozo , Ciric Jasmina , Beleslin Biljana , Marina Djordje , Stojkovic Mirjana , Zarkovic Milos

The aim of the study was to assess the influence of thyroid hormones on lipid profiles in primary hypothyroidism, in order to determine the most influential one for the clinical follow-up. Study group included 15 subjects (3 male, 12 female, age 46±13 years/mean±S.D.), and total and free T4, total and free T3 and TSH, total, HDL and LDL cholesterol, triglycerides, ApoA, ApoB and Lp(a) were determined. The diagnosis of primary hypothyroidism was based o...

ea0014p370 | (1) | ECE2007

Hypothyroid Graves’ ophthalmopathy: a case report

Ciric Jasmina , Zarkovic Milos , Beleslin Biljana , Stojkovic Mirjana , Savic Slavica , Trbojevic Bozo

Background: Hypothyroid Graves’ ophthalmopathy is a rare condition, present in about 3% of all cases. Since thyroid-stimulating antibodies could be detected in a majority of euthyroid and hypothyroid Graves’ patients, the most probable explanation for unincreased thyroid function is a reduction of tissue capability to response to stimulation.Case report: A 57-yr-old man visited the hospital with signs and symptoms typical of hypothyroidism. Sin...

ea0014p649 | (1) | ECE2007

Insulin levels and lipid profile in lean women with polycystic ovary syndrome

Stojkovic Mirjana , Zarkovic Milos , Ciric Jasmina , Beleslin Biljana , Savic Slavica , Marina Djordje , Trbojevic Bozo , Drezgic Milka

Background: Women with polycystic ovary syndrome (PCOS) appear at increased cardiovascular risk due in part to a dyslipidemia characterized by increased plasma triglyceride and reduced high density lipoprotein (HDL) cholesterol levels. Insulin resistance is one of the features of PCOS and potentially affect lipid metabolism.Objectives: The aim of this study was to compare basal insulin levels and lipid profile in lean women with PCOS with weight matched ...

ea0056p1059 | Thyroid (non-cancer) | ECE2018

Metabolic profile in patients with subclinical hypothyroidism

Stojkovic Mirjana , Savic Slavica , Ciric Jasmina , Nedeljkovic-Beleslin Biljana , Stojanovic Milos , Zarkovic Milos

Background: Thyroid function regulates a wide array of metabolic parameters and significantly affects lipoprotein metabolism. Subclinical hypothyroidism (SCH) is the most common thyroid disorder, with a prevalence up to 10% in adult populations. Subclinical hypothyroidism is defined as mild elevation in thyroid stimulating hormones (TSH) in presence of normal free thyroxine (fT4) and free triiodothyronine (fT3). This mild elevation of serum TSH is caused by a minor initial dec...

ea0049ep111 | Clinical case reports - Pituitary/Adrenal | ECE2017

Primary adrenal insufficiency and pregnancy – a case report

Savic Slavica , Stojkovic Mirjana , Nedeljkovic-Beleslin Biljana , Nisic Tanja , Stojanovic Milos , Miletic Marija , Ciric Jasmina , Spremovic-Radjenovic Svetlana , Zarkovic Milos

Primary adrenal insufficiency (PAI) is uncommon in pregnancy. Women with PAI have reduced fertility and parity. If unrecognized or untreated during pregnancy PAI increases risk for maternal and foetal morbiditiy and mortality. Majority of women diagnosed before conception and appropriately treated, have uneventful pregnancies, with increased risk of cesarean section (CS) and preterm delivery.We report a 38-year-old woman with PAI during first spontaneus ...

ea0041ep330 | Clinical case reports - Thyroid/Others | ECE2016

Importance of levothyroxine absorption test in identifying malabsorption as a cause of inadequate substitution for hypothyroidism

Lalic Tijana , Ciric Jasmina , Beleslin Biljana , Stojkovic Mirjana , Savic Slavica , Nisic Tanja , Stojanovic Milos , Barac Marija , Zarkovic Milos

Introduction: The most common cause for persistent elevation of TSH levels in hypothyroid patients treated with levothyroxine is poor compliance. The levothyroxine absorption test (LAT) is usually confirmed this phenomenon called “pseudo-malabsorption”.Case report: Sixty-year-old female, weight 60 kg, BMI 24.3 kg/m2, presented with sleepiness, tiredness, fatigue and forgetfulness. Her skin was very dry and flaky. She had low toleranc...

ea0037ep287 | Calcium and Vitamin D metabolism | ECE2015

Bones in pseudohypoparathyroidism type 1a

Savic Slavica , Nisic Tanja , Lalic Tijana , Nedeljkovic-Beleslin Biljana , Stojkovic Mirjana , Barac Marija , Stojanovic Milos , Ciric Jasmina , Zarkovic Milos

Pseudohypoparathyroidism type 1a (PHP1a) is disorder characterised by resistance to the biological actions of circulating parathyroid hormone (PTH) along with typical features of Albright’s hereditary osteodystrophy (AHO). Tissue-specific imprinting of GNAS gene results in complete resistance to PTH in renal proximale tubule, but skeletal responsiveness to PTH appears intact, since Gαs is biallelically expressed in human bones. The objective of this study was to dete...