Endocrine Abstracts

Introduction: Type 1 diabetes mellitus (T1DM) and celiac disease are two frequently associated autoimmune pathologies. The association with hepatomegaly raises discussion of many diagnosis.Case presentation: We report the case of a 12-years-old T1DM girl admitted at department C of the national institute of nutrition of Tunis for diabetic ketosis. She has T1DM since 5 years, with poor glycemic control (HbA1C=10%) and poor therapeutic adherence. On examin...

Introduction: Type 1 diabetes and celiac disease are two autoimmune pathologies that frequently coexist. This association implies specific nutritional management whose application by the patient is not always simple. We report An extream case of malabsorption in a patient with type 1 diabetes and celiac disease.Case presentation: This was the case of a 34-year-old with type 1 diabetes (T1D), celiac disease and vitiligo evolving since 13, 7 and 2 years re...

Introduction: The aim of our study was to evaluate the weight status of a population with type 2 diabetes and with diabetic peripheral neuropathy, and to study its association with hyperalgesic diabetic peripheral neuropathy.Methods: This was a cross-sectional study about 100 T2DM patients hospitalized in department C of the national institute of nutrition of Tunis, and having diabetic peripheral neuropathy, diagnosed using the monofilament test and the ...

Introduction: Primary hyperparathyroidism affects 0.3% of the general population1. 90% are due to single parathyroid adenoma1. Surgical treatment is the only definitive cure2. Improvements in imaging permit radiologists to better identify parathyroid adenomas1, enabling more targeted surgery1, thus shortening general anaesthesia, as well as lowering post-operative complication rates. Neck ultrasound (US) and parathyroid sc...

Background: Elevated low-density lipoprotein cholesterol (LDL-C), which arises due to genetic and environmental factors, has a causal role in the pathogenesis of cardiovascular disease (CVD). Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are approved for patients with familial hypercholesterolaemia (FH) and patients at high risk of CVD due to non-familial hypercholesterolaemia (non-FH). In clinical trials, PCSK9 inhibitors are well-tolerated and lead to redu...

Introduction: Adrenal incidentaloma prevalence is rising with the advancement of imaging techniques. The hormonal work-up should always include free metanephrines for the diagnosis of a pheochromocytoma and 1 mg overnight dexamethasone suppression test for the diagnosis of autonomous cortisol secretion. These tumors have two distinct embryologic origin and don’t usually coexist, and when they do, it occurs in case of an ectopic adrenocorticotropic hormone (ACTH) productio...

Introduction: Hypocalcemia is a well-known complication of total thyroidectomy. Usually, it’s a reversible and a transitory complication. However, it requires a regular check-up.Objective: The aim of this study is to determine the epidemiological and the therapeutic characteristics of hypocalcemia after total thyroidectomy.Methods: This is a retrospective study about 106 cases of total thyroidectomy that operated between the y...

Background: Overweight is becoming increasingly more common among patients with inflammatory bowel disease and plays a role in the development and course of the disease especially in Crohn’s disease (CD). However, there is currently little data on his impact on the evolutionary genius of CD. The aim of this study was to assess the impact of overweight on the epidemiological, clinical, therapeutic and progressive characteristics of CD.Patients and Me...

Introduction: In recent decades, metabolic diseases have continued to increase. Several investigations concerning the origin of these diseases such as dyslipidemia, hypercholesterolemia, diabetes, etc., have been elucidated. These pathologies have been attributed to lifestyles and mainly to diet. Obesity is a serious metabolic and energy disorder, which has become a real major public health problem. Materials and methodsWe were interested in studying the effect of a high-fat d...

Introduction: Cervical thymic cysts are among the rarest congenital neck masses. Thymic migration into the superior mediastinum during organogenesis explains the topography and diversity of clinical presentations of these cysts. Due to the possibility of mediastinal extension, the management of these lesions is different than other congenital neck masses. The aim of our work is to present the clinical, radiological, and therapeutic features of cervicomediastinal thymic cysts.<...