Endocrine Abstracts

Introduction: Graves’ disease is a multi-system autoimmune disease characterized by hyperthyroidism, ophthalmopathy and pretibial myxedema. The disease presents with hyperthyroidism or more rarely with ophthalmopathy. It runs a various course and many times during its natural course permanent hypothyroidism may ensue.Aim: The aim was to describe the case of a patient with Graves’ disease presenting with ophthalmopathy and subclinical hypothyroi...

Primary hyperaldosteronism may be due to an adrenal adenoma and is an increasingly recognized cause of secondary arterial hypertension. The disease causes hypokalemia and is usually treated surgically by excision of the adrenal adenoma. However, it appears that it may present with a clinical profile without arterial hypertension. The aim was to describe three cases of primary hyperaldosteronism who presented with hypokalemia and an adrenal adenoma with normal blood pressure. A...

Lithium is considered a mainstay treatment option for the management of bipolar affective disorder. However, lithium administration is characterized by endocrine effects. The aim was to present the case of a patient who was on treatment with lithium for many years for the management of bipolar affective disorder and presented with a large parathyroid adenoma causing clinical hyperparathyroidism with severe hypercalcemia who was successfully treated by surgical excision of the ...

Morbid obesity is accompanied by multiple comorbidities and may be associated with a high mortality risk. Cardiac manifestations accompany morbid obesity and may account for the increased morbidity and mortality risk which accompanies the disorder. However, cardiac insufficiency as the first cardiovascular manifestation in morbid obesity is a less recognized comorbidity. The aim was to describe cardiac insufficiency as the first cardiovascular disease manifestation in morbid o...

Euthyroid sick syndrome also known as nonthyroidal illness syndrome is the reaction of the thyroid gland to severe disease. The SARS-CoV-2 virus affects the thyroid gland and may cause subacute thyroiditis, autoimmune Hashimoto’s thyroiditis, Graves’ disease, exacerbation of Graves’ disease and a form of silent thyroiditis. The aim was to study thyroid hormone levels and identify the presence of euthyroid sick syndrome in the context of severe SARS-CoV-2 disease...

Introduction: The SARS-CoV-2 virus has severely affected humanity. The disease causes pneumonia which may be severe. In many cases, patients, especially if there are comorbidities, may have a fatal outcome. The disease affects all organs and the variability of its manifestations has attracted intense scientific interest. Aim: The aim of the study was to describe the case of a patient who developed subacute thyroiditis after infection with the SARS-CoV-2 ...

Introduction: Leukopenia is a manifestation of autoimmune diseases such as systemic lupus erythematosus (SLE). Leukopenia may be an early sign of autoimmunity and may be a comorbidity in patients with autoimmune Hashimoto’s thyroiditis. Aim: The aim was to present a cohort of 12 patients with autoimmune Hashimoto’s thyroiditis who presented with leukopenia.Methods: A cohort of 12 patients, aged 19-72 y, female, with autoi...

Introduction: Hashimoto’s thyroiditis is known to induce nodularity in the thyroid and in some cases to coexist with papillary thyroid carcinoma. However, the effect of the development of Hashimoto’s thyroiditis on the course of nodular goiter is not known.Aim: The aim was to describe the effect of the development of Hashimoto’s thyroiditis in the course of nodular goiter.Methods: A cohort of 12 patients, female, age...

Introduction: Patients with systemic sclerosis may develop cancer. The development of malignant hematological diseases has also been described in patients with systemic sclerosis. These patients may also be prone to the development of lymphoma, in most cases a B-cell lymphoma.Aim: The aim was to describe the case of a patient with systemic sclerosis who had a non-Hodgkin’s lymphoma and developed primary hypothyroidism.Case rep...

Introduction: Diseases of the gastrointestinal tract may have on effect on bone quality manifesting either as osteomalacia or as osteoporosis. Gastritis may have an effect on bone as it requires long term treatment with proton pump inhibitors. Gastrointestinal neoplasms may be accompanied by nutrient malabsorption. These diseases may also be related with vitamin D deficiency.Aim: The aim was to describe two cases of gastrointestinal diseases, namely chro...