Endocrine Abstracts

ObjectiveTo determine the clinical, biological and etiological aspects of hirsutism.MaterialA retrospective study from 2009 to 2017 included 51 patients explored and followed for hirsutism in the endocrinology department of the Rabta hospital.ResultsThe mean age of hirsute patients was 29 years, their average age of menarche was 12 years old. Hirsutism appeared be...

A 45-year-old female presented with secondary amenorrhea. Since menarche, her period has been irregular, which she initially managed with oral pills, which were discontinued in 2009. Subsequently, she does have complete secondary amenorrhoea. She has hirsutism at the age of 20. Which was initially well controlled with oral contraceptive pills but has been getting worse over the years. Ferriman-Gallwey’s score was high. She also stated that her weight had been steadily inc...

Background: Steroid cell tumour of ovaries comes under sex cord stromal tumour that accounts less than 0.1% of all ovarian tumour. Majority are benign in childhood age group. It may produce steroids and testosterone resulting in virilisation and Cushing’s syndrome. Histology remains the gold standard for diagnosis of NOS. The gross appearance of NOS generally is well circumscribed, solid and noncalcifed with a lobulated appearance Till date only 10 cases has been reported...

Introduction: Non-classical congenital adrenal hyperplasia (NCCAH) is considered to be a common monogenic inherited disease, with an incidence range from 1:500 to 1:100 births worldwide. NCCAH is often peri or post pubertal pauci or even asymptomatic. We report the case of a young girl with severe hirsutism and sexual ambiguity, despite late disclosure.Observation: This is the case of a 16-year-old girl, with a history of menarche at the age of 14, prese...

Introduction: Polycystic ovary syndrome is the most common cause of anovulatory infertility in women. Anti-Mullerian Hormone (AMH) was considered a reliable marker for the diagnosis of polycystic ovary syndrome (PCOS). However, AMH level is influenced by age and body mass index. The aim of this study was to analyze the performance of the (LH x AMH)/FSH ratio in the diagnosis of PCOS in women with morbid obesity.Methods: This was a cross-sectional study i...

Introduction: Hirsutism is often caused by hormonal disorders such as high levels of circulating androgens, hormonal changes related to menopause or disorders of the ovarian or adrenal gland. The aim of our study was to evaluate the clinical and etiological profile of hirsutism.Methods: A retrospective study was conducted at the endocrinology department of Rabta Hospital in Tunis including 100 patients who presented with hirsutism between January 2009 an...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Introduction: The polycystic ovary syndrome is the commonest cause for hyperandrogenism in young women. However, in older women, adrenal and ovarian tumours are more common, particularly if (a) hyperandrogenism is of short duration, (b) causes significant clinical androgenisation, and (c) is biochemically severe. We present an elderly woman who presented diagnostic and therapeutic challenges on account of her comorbidities.Case Present...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Introduction: The polycystic ovary syndrome is the commonest cause for hyperandrogenism in young women. However, in older women, adrenal and ovarian tumours are more common, particularly if (a) hyperandrogenism is of short duration, (b) causes significant clinical androgenisation, and (c) is biochemically severe. We present an elderly woman who presented diagnostic and therapeutic challenges on account of her comorbidities.Case Present...