Endocrine Abstracts

Objective: Pregnant women with autoimmune (subclinical) hypothyroidism have an increased risk of developing gestational diabetes mellitus (GDM). However, this association remains controversial in euthyroid women with thyroid autoimmunity (TAI). Therefore, the aim of the study was to determine the association between TAI and GDM in euthyroid women in a logistic regression analysis with adjustments for baseline/demographic parameters.Methods: Cross-section...

Phytotherapy is the integral part of the combined treatment for diabetes mellitus. A large number of plants possessing hypoglycemic activity are described in the literature, but only small part of them is in use. Hypoglycemic effect of medicinal plants is preconditioned by the wide spectrum of compounds with biological activity in their composition. Flowers of carthamus (Carthamus tinctorius) and leaves of celery (Apium graveolens) are known to possess a numb...

Objective: Papillary thyroid carcinoma is the most common malignant tumor of the thyroid, the diffuse sclerosing variant is however very rare and represents between 0.7 and 6.7% of all papillary thyroid carcinomas. We propose through this poster to study its clinical, epidemiological, therapeutic and prognostic characteristics.Matherials and methods: We report two cases of diffuse papillary sclerosing carcinoma of the thyroid, collected at the ENT and CC...

The goal of this study is to examine the role of surgery in the treatment of Graves’ disease and to assess the surgical outcomes.Methods: We present the results of a retrospective analysis of 31 Graves’ disease cases operated on in the ENT and cervico-facial surgery departments of Farhat Hached Sousse Hospital during a six-year period [2015-2021]. Our group consisted of 05 males and 26 women. The average age ranged from 12 to 70 years. Between ...

Thyroid surgery is a frequent procedure that has certain risks. After a complete thyroidectomy, hypocalcemia is the most prevalent consequence. It has a variety of causes, with hypoparathyroidism being the most frequent and dangerous.Materials and procedures: A retrospective analysis collected 27 cases of patients who had a total thyroidectomy complicated by hypocalcemia among 320 patients who underwent a total thyroidectomy throughout the study period, ...

The goal of this paper is to analyze the factors that cause people to flee medical treatment and to put forth management guidelines. Materials and methodes: This is a retrospective analysis of 27 instances with Graves’ disease that were resistive to medical treatment after escaping from well-conducted medical treatment in the ENT and cervico-facial surgery departments at Farhat Hached Sousse Hospital over a six-year period [2015-2021]. Results: All of the patients were pu...

Context/Objective: Evidence on the impact of thyroid hormone treatment (LT4) on pregnancy outcomes in women with subclinical hypothyroidism (SCH) without TPOAb remains scarce. We assessed this relationship in a single centre in a real-world setting.Design, Setting, Participants: Cross-sectional study in 1460 women screened for TSH, free T4 and thyroid peroxidase antibodies (TPOAb) at median 13 (11-17) weeks of gestation, during the period 2013-2014. Excl...

Introduction: The main objective in the management of primary hypothyroidism is to normalize thyrotropin (TSH) level with Levothyroxine replacement therapy. The optimal dose of Levothyroxine may be affected by several factors such as age, gender, body weight, some medical disorders and drugs intake. The aim of this study was to assess the relationship between thyroid antibody titers and Levothyroxine dose in patients with primary hypothyroidism secondary to Hashimoto thyroidit...

Introduction: Fahr syndrome is a rare entity characterized by the presence of bilateral intracranial calcifications with predilection for the basal ganglia and dentate nuclei. It is commonly associated with endocrine disorders, particularly parathyroid and Vitamin D disturbances. Herein we report a case of pseudohypoparathyroidism revealed by Fahr syndrome.Observation: A 29-old-year male was referred to our department for symptomatic hypocalcemia. He sho...

Introduction: Although the association between parathyroid and thyroid diseases is not uncommon, the coexisting of parathyroid adenoma causing primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) is rare. Probably this can be partially explained by different embryologic origin of thyroid and parathyroid cells. Herein, we report a case of PHPT associated with synchronous bifocal PTC.Observation: A 65-year-old woman was referred to our ...