Endocrine Abstracts

Introduction: Anaplastic thyroid carcinoma also known as undifferentiated carcinoma is a rare and highly aggressive malignant tumor. It continues to rank as one of the deadliest diseases worldwide and carries a very poor prognosis. It is an aggressive locoregional disease with a high metastatic capacity. There is no agreement with regards to the best treatment.Material and Methods: We reporteded 6 cases of anaplastic thyroid carcinomas treated in the ENT...

Introduction: An abnormally positioned thymus may either be aberrant or ectopic. Aberrant cervical thymus (ACT) is located along the normal pathway of descent of the thymus, with an attachment to mediastinal thymus via thymic tissue or fibrous cord in 50% of the cases. ACT is usually diagnosed within the first and second decade of life, and most lesions are cystic.Case report: We report a case of 9-year-old woman was referred to our hospital for the oper...

Introduction: Thyroid papillary microcarcinoma is a subtype of papillary carcinoma that included tumors with less than 10 mm diameter. Its therapeutic management is still a subject of controversy.Material and Methods: We conducted a retrospective study over 20 cases of papillary thyroid microcarcinoma at the ENT department of Tahar Sfar Hospital in Mahdia over 17 years (2000–2017).Results: We report 20 cases of papillary thyr...

Tashkent Pediatric Medical Institute, department of endocrinology, Center of the Scientific and Clinical Study of Endocrinology, department of neuroendocrinoloy, Ministry of Health of the Republic of Uzbekistan. Republic of Uzbekistan, 100125, Tashkent, Mirzo Ulugbek str. 56G.D Narimova., Z.Yu. Khalimova, Yu.M. Urmanova, M.I. Narimova, Sh.M. Safarova, G.O. AlimukhamedovaThe aim: To study the characteristic of the index of body weig...

Introduction: Transcriptome analysis of peripheral blood mononuclear cells (PBMC) RNA has identified a set of androgen-responsive non-coding RNAs.Aim: To quantify the androgen-responsive gene expression and investigate its relationship to the testosterone (T) rise following hCG stimulation in boys with no genetic evidence of androgen insensitivity.Methods: Boys with suspected DSD who were evaluated at the Royal Hospital for Childre...

Introduction: Transcriptome analysis of peripheral blood mononuclear cells (PBMC) RNA has identified a set of androgen-responsive non-coding RNAs.Aim: To quantify the androgen-responsive gene expression and investigate its relationship to the testosterone (T) rise following hCG stimulation in boys with no genetic evidence of androgen insensitivity. Methods: Boys with suspected DSD who were evaluated at the Royal Hospital for Childr...

Introduction: Dyshormonogenetic goiter (DG) is considered as a form of thyroid hyperplasia due to enzymatic defects in hormone synthesis. The architectural polymorphism and cellular atypia may mimic thyroid neoplasms and cause difficulties in differential diagnosis.Results: We report 3 cases of DG occurring in one females and two males who were aged 20, 9, and 7 years old, respictively. All patients presented with clinically evidence of goiter. Hypothyro...

Introduction: Remnants of the fourth branchial arch are extremely rare with less than 100 cases reported in the literature and account for 1–4% of all branchial anomalies. These anomalies typically present as recurrent neck infections and/or abscesses or acute suppurative thyroiditis. We report a case of cyst of the 4th cleft revealed by a thyroiditis treated in our department.Case report: A 6-year-old boy presented with recurrent neck swellings. Du...

Introduction: Metastases of thyroid tumors are rare. Metastatic sites are in order of frequency : pulmonary, bone and brain. Facial bones metastases are exceptional. These metastases are more frequent in vesicular than papillary carcinoma histological. The aim of our work is to describe the clinical and radiological aspects as well as the therapeutic modalities.Observation 1 and 2: A 38-year-old woman and 13-year-old boy consulted for a chronic cough wit...

Background: analysis the epidemiologic and the clinical features of this entity, then to discuss the management Patients and methods: We report a retrospective study of 120 patients operated on for multi nodular goiter over a period of 5 years between January 2017 and December 2021.Results: In our study a female predominance was noted with a sex ratio F/H of 8/1. The average age of the patients was 44 years with extremes from 15 to...