Endocrine Abstracts

Introduction: The aim of this study was to examine prognostic significance of patient-related, tumor-related and treatment-related factors for intrathyroidal papillary thyroid carcinomas (PTC), via multivariate analysis.Materials and methods: This study included 153 patients with intrathyroidal PTCs (pT1/pT2/pT3) surgically treated in our Institution during two-decade period. Patients with locally invasive tumors (pT4) and initial distant metastases (M1)...

Polycystic ovary syndrome (PCOS) is characterized by excessive androgen secretion and women with PCOS are at risk of developing anxiety disorders. Maternal testosterone levels in humans have been shown to affect brain development and to be correlated to mental function. During pregnancy, women with PCOS display high circulating androgen levels that may affect the fetus and increase the risk of mood disorders in offspring. This study investigated whether maternal androgen exces...

Introduction: The aim was to analyse usefulness of sentinel lymph node (LN) biopsy of jugulo-carotid regions after methylene blue dye mapping for selection of clinically N0 patients with medullary thyroid microcarcinomas (MTMC) and lateral LN metastases for one-time modified radical neck dissection (MRND).Materials and methods: From 2007 to 2016th, 15 patients were operated in our institution due to MTMCs with serum calcitonin levels lower tha...

Introduction: Dermoid cysts are usually presented as solitary hamartomatous tumor, containing all skin adnexa. They can be found in the skin and subcutis of the face and neck; or can be intracranial, intraspinal, or intra-abdominal, localized in the ovary or omentum. Cutaneous cysts most commonly appear on the forehead, around eyes, as well as on the floor of the mouth, rarely on the neck.Case report: We present a 24-year-old female patient with a dermoi...

Introduction: Serum calcitonin level (sCT) is a precise marker for medullary thyroid carcinoma (MTC). However, lymph node (LN) metastases can be found in lower sCT, as well, and preoperative ultrasound may provide false negative findings on regional LNs. The aim was to present original technique of sentinel lymph node (SLN) biopsy of jugulo-carotid regions, after methylene blue dye mapping procedure, and its usefulness for selection of clinically N0 patients with MTC for modif...

Introduction: Serum calcitonin levels (sCT) in medullary thyroid carcinoma (MTC) correlate with the tumour size and disease progression. Lymph node (LN) metastases can be verified even in sCT lower than 100 pg/ml. The extent of LN dissection has not yet been standardised. The aim of this pilot study was to show our experience with sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in selection of patients with MTC for modified radical neck dissection (MRND).<p ...

Background: Well-differentiated thyroid carcinoma in children is rare but it shows aggressive behaviour. Gross lymph node metastases and distant metastases are common on first clinical presentation.Patients and methods: During 33 years (1981–2014) at the Institute of Oncology and Radiology of Serbia 24 children were operated due to papillary thyroid carcinoma. Mean age was 12.6 (range 7–16) years. At the time of diagnosis 12.5% patients had lun...

Introduction: The aim of this study was to determine frequency of lymphonodal metastases in jugulo-carotid chain (JCC) and central neck compartment in incidental thyroid microcarcinomas (ITMC), as well as to examine whether sentinel lymph node (SLN) biopsy of JCC is an accurate technique to select patients with true positive, but clinically and ultrasonically negative lymph nodes, for modified radical neck dissection (MRND).Materials and methods: Out of ...

Introduction: The aim of this study was to determine whether sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in thyroid microcarcinomas (TMC) is an accurate technique to select patients with true positive, but clinically and ultrasonically N0 LNs, for modified radical neck dissection (MRND).Materials and methods: In total 199 patients with TMC underwent total thyroidectomy, central neck dissection and SLN mapping with 0.2 ml of 1% methylen...

Background: Papillary thyroid carcinoma in children and adolescents is rare but it shows aggressive behavior. Gross lymph node metastases and distant metastases are common on first clinical presentation.Patients and methods: Forty-eight children and adolescents were operated due to PTC. Mean age was 16.6 years (range 7–21). At the time of diagnosis 13% had lung metastases. Total thyroidectomy or completion of thyroidectomy was performed in all cases...