Endocrine Abstracts

An interest in art and antiques and a chance discovery in Hong Kong in 2000 led rapidly to an obsession with carvings from Northern China’s 5000 year old Hongshan Culture. The most controversial are in a unique silica glass (‘shui jing’), with a very high melting temperature (>1600 °C) and no additives or stabilisers, that could only have originated from a large unique meteorite impact. This paper will present results on the carvings of light microscopy...

Background: The lipid profile of healthy adults in northern Nigeria is scarcely reported in literature. Yet, hospital records show increasing frequency of dyslipidemia-related illnesses like CVA, MI, and peripheral vascular diseases in practice. We aim to report the pattern of lipid abnormalities in a rural population in Kano, Nigeria.Methods: A population screening of apparently healthy adults resident in sub urban community in Kano was undertaken over ...

TSH-secreting pituitary adenomas (TSHomas) are rare. Previously, the reported prevalence was one case per million populations although this is probably an underestimate. A recently published study reported a prevalence of TSHomas in Sweden of 2.8/million inhabitants.Methods/design: Observational study conducted in four tertiary referral centres in Ireland. We retrospectively collected data on the prevalence, demographics, hormonal profile, tumour charact...

An adrenal incidentaloma is defined as an adrenal mass >1 cm diameter, discovered serendipitously on radiological imaging done for another reason. They are important because a percentage will turn out to be malignant or secrete excess hormones. The aim of the current study was to ascertain if these lesions were being investigated and followed appropriately compared to American Association of Clinical Endocrinologists guidelines. All imaging reports for the calendar year 20...

Background: Vitamin D is a growing endemic problem. Wide proportions of healthy adults are deficient in vitamin D. It is very important for skeletal and non-skeletal health. It is now well established that many people have vitamin D levels that are less than currently recommended for optimal healthAim of this work: To assess vitamin-D sufficiency/deficiency in a sample of healthy Egyptian adult males in Dakahlia Governorate in Northern Egypt and correlat...

Introduction: The aim of this study was to determine the frequency and types of accompanying malignancies in Turkish subjects with differentiated thyroid cancer (DTC) residing in the northern region of Cyprus.Subjects and methods: We retrospectively analysed 567 subjects with a diagnosis of DTC in the Departments of Endocrinology and Nuclear Medicine.Results: Four hundred and forty-eight (79%) were females and 119 (21%) were males....

Introduction: National Institute of Health and Care Excellence (NICE) has provided guidance for the use of human recombinant GH in the treatment of growth failure in children. An ongoing National GH Audit was established in 2013 by BSPED to maintain a central database and gather information regarding trends in prescribing and facilitate future long-term follow up. This part of the audit looked at the trends of off label prescribing of GH.Method: Data wer...

Background: Adolescent polycystic ovarian syndrome (PCOS) is being diagnosed more frequently as the prevalence of childhood obesity increases. Adolescent PCOS has been associated with low birth weight (LBW), exaggerated adrenarche (EA) and metabolic syndrome in Mediterranean populations. This study describes the clinical phenotype of a cohort of northern European girls.Methods: A retrospective study of adolescents with PCOS, diagnosed according to the Ro...

Retinopathy is one of the more serious complications of type 1 diabetes. There is emerging knowledge re the development of retinopathy in childhod diabetes. We studied the clinical profiles of children with retinopathy in an industrial town in Northern England. The current clinic size is 160. 42 patients were identied from clinic records as having retinopathy. Formal screening is offered to all patients from age 12. The age range was 11–20 years; median age 16. 55% were f...

Approximately 25% of the reported cases of MTC are familial. Familial MTC can occur as part of MEN2-syndrome or as familial MTC alone (fMTC) defined as more than ten carriers in the kindred, or multiple carriers or affected members over the age of 50 with an adequate medical history excluding pheochromocytoma. The vast majority of MEN2 families (98%), as well as fMTC kindreds (88%) harbour a RET mutation. In MEN2A, mutations at codon-634 (exon-11) account for 85% of all mutati...