Endocrine Abstracts

Introduction: As soon as pregnancy is established, various physiological changes occur in maternal thyroid economy. Due to that, the reference limits of thyroid parameters used for the general population are no longer valid to diagnosis thyroid dysfunction during pregnancy.Methods: We included 266 pregnant women, with no thyroid disorders and resident in Cantabria, a region in northern Spain. They were questioned about iodized salt and iodine supplements...

Introduction: Vitamin D insufficiency is common in older people and is associated with several disorders related to aging such as osteoporosis, which leads to a significantly increased risk of bone fractures. This deficiency is more common in Mediterranean countries than in Northern European countries. Hypocalcemic seizures resulting from vitamin D deficiency are rare in adults, and fractures caused by seizures without evidence of direct trauma have not yet been reported.<...

Objective: To investigate comorbidity rate, symptoms, overall morbidity, medication useand use of health care services among women with polycystic ovary syndrome (PCOS).Design: Community-based prospective cohort study.Patients: Womenreporting oligo/amenorrhea and hirsutism at age 31 and/or PCOS diagnosis by age 46 (n = 280) and controls without PCOS related symptoms or diagnosis (n = 1573) in the Northern ...

Introduction: Klinefelter syndrome (KS) is generally characterized by late adolescence/young adulthood onset of primary hypergonadotropic hypogonadism. Fourteen cases have been previously reported on apparently unexplained isolated hypogonadotropic hypogonadism (IHH) in KS. Gonadotropins defect was variably associated with anosmia or other pituitary hormones deficiencies, but no cause could be clearly identified to explain the central defect. We describe the clinical and genet...

Introduction: Low vitamin D status has been associated to COVID-19 risk, and type 2 diabetic patients are a vulnerable group. Even though the Canarian archipelago is one of the sunniest spots in Europe, our prevalence of vitamin D deficit is known to be very high. The mandatory lockdown may have worsened this deficit, increasing the need for vitamin D supplementation.Objectives: Our main objective was to assess and compare the prevalence of vitamin D def...

Introduction: COVID 19 is now a global pandemic. Oxygen saturation (SpO2), male gender and diabetes have been associated as risk factors for critical care admission, intubation, and prolonged intubation in hospitalised patients. Bacillus Calmette-Guérin (BCG) vaccine may have protective role of against COVID-19Methods: We retrospectively evaluated inpatient records, of patients admitted over last three months in a public hospital in Northern India t...

Familial hypocalciuric hypercalcaemia (FHH) is an autosomal dominant disorder characterized by lifelong elevation of serum calcium concentrations with inappropriately low urinary calcium excretion. Three types referred to as FHH1, FHH2 and FHH3 and located on chromosomes 3q21.1, 19p and 19q13.3, respectively, have been reported. FHH1, caused by loss-of-function mutations of the calcium-sensing receptor (CaSR), accounts for >65% of FHH patients. To identify the gen...

Introduction and objective: The aim of this study has been to evaluate the relationship between vitamin D and iPTH levels and the status of carbohydrate metabolism in a representative sample of the Spanish population.Material and methods: The study was conducted in two population of northern and southern Spain, evaluated in the same period of time and with a similar methodology: Pizarra Study (Málaga) and Asturias Study. Subjects in both groups unde...

This cross sectional single centre study was performed at an endocrine center in northern India (latitude 29°42′N and longitude 77°02′E) to assess the prevalence of vitamin D deficiency in 234 symptomatic women presenting with musculoskeletal symptoms. The study was conducted during winter (Nov 2010–Jan 2011).Subjects were recruited from patients attending the OPD for various musculoskeletal symptoms. Inclusion criteria were sy...

Introduction: Acromegaly is a chronic disease associated with impairment of quality of life (QoL) and psychological status. The aim of the present study was to assess QoL and mood disturbance in patients with acromegaly.Description of methods/design: It was a comparative, cross-sectional study conducted in the department of Endocrinology at a tertiary medical centre of northern Greece in 2011. AcroQoL questionnaire was used to assess QoL in acromegalics ...