Endocrine Abstracts

A multidisciplinary team is responsible for the management of over 1,200 NET patients per year in our hospital. Tumor board decisions for peptide receptor radiotherapy (PRRT) are based on the Bad Berka Score which takes into account molecular imaging features and clinical aspects. The therapy plan for each patient is individualized. Retrospective analysis was performed in 1048 patients (age 4–85 years) with progressive NETs treated at our center since 2004 using Lu-177 (<...

The management of adults with congenital adrenal hyperplasia due to classic 21-hydroxylase deficiency (21OHD) is a challenging balance of hormone replacement, disease control, and avoidance of adverse effects. The approach should emphasize the clinical evaluation and patient goals, and laboratory tests are used secondarily as ancillary data. Upon transition from pediatric to adult care, the concerns shift from growth and pubertal development to fertility, neoplasia formation, ...

A 31-year-old gentleman presented to our Endocrine Services with his 20-year-old fiancée with plans for marriage and to conceive. He was diagnosed with congenital panhypopituitarism and absent pituitary stalk at the age of 4. He was started on replacement growth hormone, desmopressin, levothyroxine, hydrocortisone and testosterone, in this sequence, across the years. He underwent induction of puberty at the age of 13 years. He was noticed to have bilateral cryptorchidism ...

38 year old lady with history of thyrotoxicosis managed since 2012. She works as a bus driver and is a single mother. She had no evidence of thyroid eye disease and her clinical activity score was 0. She has a smooth goitre which is non compressive. She was previously treated with propylthiouracil and she went into remission but then she relapsed in 2018. She has been on treatment but due to being a single mother and also her work schedules, she struggles with her medications ...

A 33-year-old male with a background of idiopathic hypogonadotrophic hypogonadism was referred to the endocrine clinic to discuss fertility. He was originally diagnosed overseas when presented with delayed puberty in late teens. He had a normal pituitary MRI and since then he had been on testosterone replacement; other pituitary function was normal. He was not anosmic however no other information was available from diagnosis. When he attended the clinic the patient and his wif...

Introduction: Radioiodine (131-I) treatment for benign thyroid disease has a 70 year history. Among the radioactive isotopes, (131-I) can be used successfully. The intention of radioiodine treatment is primarily to induce a euthyroid or hypothyroid state, but in the case of large multinodular goitres, shrinkage represents a secondary aim of therapy. The optimal method for determining iodine-131 treatment doses for Toxic Thyroid nodule is unknown, and techniques have varied fro...

Aim: The aim of the study was to assess the differences between patients in remission in acromegaly and those with active ongoing disease, using cumulative GH measurement as risk factor for various complications.Methods: A retrospective observational analysis of all patients with acromegaly treated at a tertiary referral centre since the initiation of service (~50 years) was conducted. Cumulative GH exposure was calculated as a sum of averages of GH leve...

Increased waist circumference is a cardiovascular risk factor, currently we have the cutoff value of International Diabetes Federation (IDF) or by Latin-American standards; in Colombia has not studies where showing the relationship between increased waist circumference and the risk of diabetes. This study aims to show the relationship between increased waist circumference by IDF criteria or Latin-American criteria and the risk of diabetes.Methodology: Cr...

In the 60 years since primary aldosteronism (PA) was described, our understanding of its pathophysiology and approaches to diagnosis and treatment has improved remarkably. Despite this progress, <1% of patients with PA are ever screened for this condition, which accounts for 5–8% of hypertension (HTN). The resistance to screening for PA probably derives primarily from the complexities and uncertainties inherent in its evaluation and management. How many types of PA ex...

Pre-gestational diabetics frequently rise to the challenge of pregnancy with remarkable improvements in diabetic control. Optimising pregnancy outcomes necessitates rigorous diabetes self-care, which is critically dependent on women’s capacity and the support they receive. The aim of this study was to identify self-reported drivers and inhibitors of self-care in pre-gestational diabetic pregnancies. The study was carried out at a tertiary referral maternity unit. Convenie...