Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep716 | Pituitary and Neuroendocrinology | ECE2023

Coexistence of acromegaly and Xanthomatous Hypophysitis

Uzman Rukiye Dilara Tekin , Burhan Sebnem , Dogukan Fatih Mert , Kocak Burak , Hatipoglu Esra Suheda , Niyazoglu Mutlu

Introduction: Hypophysitis is a rare pituitary inflammation due to primary and secondary causes. Xanthomatous hypophysitis is the rarest subtype and described with lipid-laden cystic areas, transparent cytoplasmic and lipid-laden histiocytes and foamy (xanthomatous) histiocytes. Although the etiology of xanthomatous hypophysitis is not clearly known, it has been suggested to develop as a result of autoimmune cause or inflammatory process of infiltration of cyst components from...

ea0090ep756 | Pituitary and Neuroendocrinology | ECE2023

Intrasellar ectopic salivary gland rests related with Rathke’s cleft cyst

Burhan Sebnem , Uzman Dilara , Erkan Buruc , Kocak Burak , Doğukan Fatih Mert , Niyazoğlu Mutlu , Hatipoğlu Esra Şuheda

Introductıon: Rathke’s cleft cysts (RCCs) are benign lesions originating from the epithelial remnants of Rathke’s pouch with a peak incidence at 30–50 years of age. It is detected at a rate of 13–33% in several autopsy series. RCC is usually asymptomatic and diagnosed incidentally. In symptomatic cases, common symptoms are headache, visual disturbance, and symptoms related to hypopituitarism.Case: A 28-year-old male patient prese...

ea0099ep103 | Pituitary and Neuroendocrinology | ECE2024

Acromegaly of immature PIT-1 origin

Unver Ozkahraman Aysel , Doğukan Mert , Kandemir Alibakan Ozlem , Kocak Burak , Akpınar Ebubekir , Niyazoğlu Mutlu , Şuheda Hatipoğlu Esra

Introduction: Acromegaly is a rare pathological condition characterized by excessive growth hormone (GH) secretion, leading to elevated levels of insulin-like growth factor 1 (IGF-1). According to the 2022 World Health Organization classification, GH-secreting pituitary adenomas fall under the PIT1-lineage. Pure GH-secreting adenomas selectively release growth hormone and may exhibit dense or sparse granulation patterns. Other subtypes include mammosomatotroph adenomas, mature...

ea0073ep169 | Pituitary and Neuroendocrinology | ECE2021

Multiple endocrine neoplasia type 1: clinical features, diagnostics

Burak Andrew

BackgroundIn medical practice, there occurs an increasingly common pathology of various endocrine and not only these organs, which is known as multiple endocrine neoplasia – MEN syndrome, which, depending on the affected organs, is classified as MEN type 1, MEN type 2 and MEN type 3. Multiple endocrine neoplasia type 1 (MEN-1, Wermer syndrome) is a rare hereditary disease with an autosomal dominant type of inheritance characterised by high penetranc...

ea0073aep244 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Optimization of surgical treatment of patients with diabetic foot syndrome

Andrew Burak

BackgroundThe development of purulent-necrotic complications of the lower extremities is one of the most dangerous complications of diabetes. According to the Internationale Diabetes Federation, the number of hospitalized patients with foot lesions due to diabetes is 25–47%, and subsequently causing high amputations in 12% of such patients. That is why the comprehensive approach of the surgeon and endocrinologist is the key to successful treatment o...

ea0014p33 | (1) | ECE2007

Abnormal glucose challenge test reflects mild gestational diabetes

Kafkasli Ayse , Cikim Ayse Sertkaya , Selcuk Engin Burak , Dogan Kezban , Burak Feza , Yologlu Saim

Objective: The status of carbohydrate metabolism of pregnant women with positive glucose challenge test (GCT), but normal oral glucose tolerance test (OGTT); and their neonates have not defined clearly.Methods: Pregnant women with normal GCT (n: 120), with abnormal glucose challenge test (AGCT) but normal OGTT (n: 67) and those with gestational diabetes (GDM) (n: 67) were included into the study. Local ethical committee approval was ...

ea0035p23 | Adrenal cortex | ECE2014

A case of an accessory spleen mimicking a nonfunctional incidentaloma

Ersoy Kerem , Anaforoglu Inan , Kece Can , Kocak Gulgun

Introduction: The diagnosis of an increasing number of adrenal tumors, so-called ‘incidentalomas’, is the result of technological advances in imaging such as abdominal ultrasonography (USG), computed tomography (CT) and magnetic resonance imaging (MRI). We present a case of an accessory spleen mimicking a nonfunctional incidentaloma.Case: An 18-year-old boy was referred for evaluating of left adrenal mass that was detected by USG performed for ...

ea0029p1854 | Thyroid cancer | ICEECE2012

Diffuse Large B Cell Lymphoma of Thyroid Gland Presenting With Acute Tracheal Compression

Incecayir O. , Anaforoglu I. , Kocak G. , Karyagar S. , Algun E.

Introduction: Non-Hodgkin lymphoma (NHL) involving the thyroid gland constitutues 2–3% of all NHL cases, 2–8% of all thyroid malignancies. The majority of lymphomas arising in the thyroid gland are MALT lymphomas and diffuse large B cell lymphomas commonly occuring in the setting of thyroiditis. Most cases are seen in adult or elderly females. The thyroid enlargement is often rapid and can lead to symptoms of tracheal or laryngeal compression. Herein, we present a ca...

ea0084op-05-26 | Oral Session 5: Autoimmunity | ETA2022

Prospective single blind, usa-based, multicenter comparison of tsh-receptor antibody immunoassays

Lupo Mark , Little Amy , Hatun Burak , Kahaly George

Objective: The performance of two functional bioassays and two immunoassays for the measurement of TSHR-Ab was assessed in this multicenter study.Methods: Two-hundred two subjects (median age 54 years, 162 female, 80%), with well-documented thyroid disorders and controls were prospectively enrolled in a consecutive, unselected manner. Antibody measurements were performed in a blinded manner using the Bridge (Siemens, performed at the Dartmouth-Hitchcock ...

ea0035p1127 | Thyroid Cancer | ECE2014

Puca Entela , Koza Kadir Burak , Puca Edmond , Ylli Agron

Hashimoto’s thyroiditis (HT) is found in a high proportion of resected thyroid specimens. There has been considerable controversy as to whether having HT predisposes a patient to papillary thyroid cancer (PTC) and conflicting data have been reported with regard to HT and risk of malignancy. The aim of this study was to evaluate coexistence of PTC with HT.Materials and methods: This is a retrospective study done at American Hospital 2 from April 2011...