Endocrine Abstracts

Introduction: Acromegaly is a quite rare and insidious disease caused by the oversecretion of growth hormone and subsequently insulin - like growth factor 1. Recent studies have demonstrated an increased co-existence of different thyroid lesions with acromegaly. However the data concerning this co-occurrence remains a matter of debate. The purpose of this study is to shed light on the different thyroid lesions concerning the patients with acromegaly who are followed up in the ...

Introduction: Acromegaly is a rare chronic, and disfiguring endocrine disorder characterized by growth hormone excess, that carries a significant burden of cardiovascular morbidity and mortality; and still unfortunately one of the most important cause of death in acromegaly. The purpose of this study is to describe the cardiovascular events and risk factors concerning patients with acromegaly who are followed up in the endocrinology department of Oujda’s Mohammed VI unive...

Introduction: Maturity Onset Diabetes of the Young (MODY) is a monogenic form of non-insulin-dependent diabetes that classically presents in a lean individual with non ketotic hyperglycaemia and an autosomal dominant inheritance pattern. The diagnosis remains a challenge and may be made by careful clinical evaluation, but exact sub-typing is possible only by genetic analysis.Materials and methods: This is a prospective data analysis in the diabetology-en...

Introduction: Turner syndrome occurs in one out of every 2,500 to 3,000 live female births. The syndrome is characterized by the partial or complete absence of one X chromosome (45,X karyotype)(1). Patients with Turner syndrome are at risk of congenital heart defects, and is defined by the association of a dysmorphic and malformative syndrome, the main elements of which are small size and gonadal dysgenesis(2).Methodology: Descripti...

Ramadan is a holy month in the Muslim religion, it involves a period of daily fasting from sunrise to sunset, which means an average of fifteen hours of fasting during the day (twelve to eighteen hours depending on seasons and regions). In diabetics, this involves metabolic disorders related to fasting, food mode (quantitative and qualitative change in dietary intake). The objective of our study is to define the profile of diabetic patients seen in the emergency department and...

Introduction: Acromegaly is a rare disease characterized by somatotropic hypersecretion. The disease is associated with multiple significant comorbidities and increased mortality. The purpose of this study is to describe the epidemiological, clinical, para-clinical and therapeutic features of Acromegaly disease.Patients and Methods: This is a retrospective study including 12 patients with acromegaly in the Endocrinology Diabetology Department of Oujda&#8...

Secondary amenorrhea is defined as the cessation of regular menses for three months or the cessation of irregular menses for six months (1). Most cases of secondary amenorrhea can be attributed to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, or primary ovarian insufficiency the aim of this study to analyze the clinical, biological, etiological profile of secondary amenorrhea (2).Patients and methods: We conducted a retrospectiv...

Introduction: Turner syndrome is a chromosomal abnormality that affects phenotypic females who have one intact X chromosome and complete or partial absence of the second sex chromosome. In this genetic disease, the karyotype ranges from complet 45, X to forms of mosaicism in which a normal cell line (46, XX or 46, XY) or a second (or third) abnormal cell line is found. Mosaic turner syndrome (MTS) has a heterogeneous clinical presentation as well as a varied presence of malfor...

Introduction: Growth hormone deficiency (GHD) associated with a congenital malformation of the hypothalamic-pituitary axis is rare. It can be isolated or part of a combined pituitary deficiency. The purpose of our work is to describe the clinical picture in which between GH deficiency in children.Materials and methods: This is a retrospective study of 18 cases among 192 patients consulting for growth retardation, conducted in the Endocrinology Diabetolog...

Background: Neuroendocrine tumors (NETs) represent a heterogenous group of neoplasms and their diagnosis can be challenging. In 2019, FDA approved 68Gallium labeled DOTATATE PET tracer for SSTR2 overexpressing NETs, which has been widely adopted since. However, limitations of 68Ga-DOTATATE have led to the development of additional radiotracers for the diagnosis of NETs. Herein we report on a novel PET tracer using 43Sc for DOTATATE labeling. <s...