Endocrine Abstracts

Introduction: Endocrine complications are common in beta thalassemia major (BTM) patients receiving blood transfusions. Chelation therapy has a role in preventing such complications. However, patients may have difficulties adhering to chelation therapy. We aimed in this study to determine the endocrine complications in BTM patients.Methods: This was a descriptive study with cross-sectional data collection over a 6 month period from February 2022 to July ...

Medullary thyroid cancer (MTC)is a very polymorphic tumour, it remains difficult to diagnose, especially in cytology. The MTC is characterized by a polymotphic cell population, the amyloid stroma is found in 43 to 81% of cases. In this retro and prospective study carried out over 5 years, we included 45 lesions (8 nodules, 35 lymph nodes and 2 cervical masses) these lesions were punctured and the cytological results were compared with the definitive histology. On cytology, 13 ...

Medullary thyroid carcinoma (MTC) is a rare but relatively serious disease, whose prognosis depends on the stage of the tumor and the quality of the initial surgical treatment. The determination of the plasma calcitonin; cervical ultrasound, and fine needle aspiration biopsy are first line examinations; nevertheless they do not always make it possible to make a certain diagnosis in preoperative; moreover they do not define the MTC nodule in a multi nodular goiter and the metas...

Introduction: Klinefelter syndrome is a genetic condition that results when a boy is born with an extra copy of the X chromosome. Klinefelter syndrome is a genetic condition affecting males, and it often isn’t diagnosed until adulthood. It is manifested by gynecomastia, small testicles, erectile dysfunction, infirtility …Observation: 70-year-old male patient with motor and cerebral infirmity, several fractures following minimal trauma. Hospita...

Cowden’s syndrome (CS), also called multiple hamartoma syndrome is an orphan pathology which associates pathognomonic cutaneous-mucosal manifestations with multiple and disseminated hamartomas (skin, mucous membranes, gastrointestinal tract, thyroid, breasts and genitourinary system) and an increased risk of the development of certain malignant tumors, in particular breast, thyroid and endometrial tumors, which are very serious.Observation<p cla...

Introduction: Hypercalcemic crisis is a rare therapeutic emergency, but one that should not be overlooked, particularly during pregnancy, when it is associated with significant maternal-fetal morbidity. The most frequent etiology is PHPT, including during pregnancy.Observation: We report the case of a 34-year-old patient with no particular pathological history, pregnant at 34 weeks of amenorrhea, who presented with acute cholecystitis. The blood test sho...

Background: Hyponatremia in not uncommon in elderly. Common causes include medication, heart, kidney and liver diseases, digestive loses, syndrome of inappropriate anti-diuretic hormone. Hormonal imbalances are sometimes overlooked. Sudden onset after a recently invasive procedure could challenge the diagnostic.Methods: We present a case report of a severe hyponatremia diagnosed after a coronary angiogram. It is a rare case of hypopituitarism secondary t...

Case history: A 26-year-old man was referred to the Endocrine Clinic due to lack of erections and infrequent shaving for 12 months. An extensive past medical history was noted, the majority of which was attributed to a diagnosis of cerebral palsy. Problems included feeding difficulties from birth with NG, followed by PEG feeding from age 3 to 20, gross motor, speech and language developmental delay, bilateral severe hearing impairment necessitating hearing aids, long sightedne...

Introduction: The number of elderly with cognitive decline has been increasing. Several studies have shown that diabetes is a risk factor for cognitive impairment. Chronic hyperglycemia is implicated, probably by promoting the development of cerebral microvascular disease but physiopathology is complicated.Methods: The study involved thirty-seven diabetic patients hospitalized in the department C of National Institute of Nutrition and Food Technology of ...

Hyperthyroidism is a clinical situation characterized by an excess of thyroid hormones in the circulation, the most common etiology of which is Graves’ disease. Its treatment is based on ATS, iodine 131 and surgery. The iratherapy, object of our study, is a treatment of current practice. It is a simple and radical treatment whose goal is to switch to euthyroidism or hypothyroidism. In case of failure or recurrence, a 2nd or even a 3rd cure is prescribed. We conducted a re...