Endocrine Abstracts

Aim: Traumatic brain injury (TBI) is known to be associated with pituitary insufficiency (PI). We have recently shown that there was a relationship between miR-126-3p, miR-3610 and PI developing in follow up of patients with TBI. In this study, we aimed to test the effects of miR-126-3p on hypothalamus pituitary-adrenal (HPA) and Growth hormone-Insulin like growth factor (GH-IGF-1) axes.Materials and methods: miR126-3p microinjection was performed to mou...

Aim: We had the aim to determine the insulin treatment strategy that could prevent or decrease the occurrence of hypoglycaemia while providing better regulation of blood glucose in Tip 2 diabetic patients with cardiac failure.Method: The patients demonstrating similar characteristics with respect to the age, body mass index, the duration of diabetes and heart failure were randomized into two groups as insulin glargine (n: 19) and NPH (n: 11...

Background: Neck ultrasonography (USG) is an important imaging tool in the postoperative follow-up of papillary thyroid carcinoma (PTC). Sarcoidosis is an inflammatory disease characterized by non-caseating granulomas with involvement in various organs and lymph nodes. Herein, a case with atypical lymph nodes detected on neck USG during routine follow-up for PTC and diagnosed with sarcoidosis will be presented.Case presentation: A 52-year-old female pati...

Introduction: Riedel’s thyroiditis (RT) is a rare and chronic fibro-inflammatory disease firstly described by Riedel in 1896. It is characterized by a dense fibrosis that replaces normal thyroid parenchyma. The fibrotic process invades adjacent structures of the neck and extends beyond the thyroid capsule, which differentiates RT from other inflammatory or fibrotic disorders of the thyroid. The overall incidence in outpatients is 1.06 per 100 000. We presented here a case...

Introduction: Prolactinomas are the most common pituitary tumors. Macroadenomas are rarely seen. Dopamine agonists such bromocriptin and cabergoline are the preferred treatments for prolactinomas. Herein, we report a patient with macroadenoma whose adenoma has resolved rapidly with cabergoline treatment.Case: A 49 year old male patient evaluated for weakness and headache. After detection of central hypothyroidism he was referred to our department. His pr...

Introduction: In rheumatological diseases have been observed in a rate of 0.8% of non-traumatic insufficiency fractures. The most common sites of insufficiency fractures are pelvis, sacrum, tibia, the sections near to the insertion of the fibula, calcaneus and buttocks. Generally, bone – joint involvement in rheumatic diseases and osteoporosis connected with prolonged use of corticosteroids prepares the ground for these insuffiency fractures. In this case, We aimed to pre...

Aim: Differentiated thyroid carcinomas (DTC) composes 95% of all thyroid malignancies originating from thyroid follicular epithelial cells. DTC expresses TSH receptors so long time TSH stimulation may cause cancer occurrence or malignancy progression. So we aimed to assess the role of TSH levels in predicting thyroid cancer stage or aggressiveness.Methods: We retsopectively searched thyroid cancer patients fort he last 10 years in our instution. Totally ...

Pitüitary ACTH deficiency is one cause of secondary adrenal insufficiency. Genetic factors, autoimmunity, infiltrative disease, cranial trauma can cause ACTH deficiency. Hyperpigmented skin lesions are expected in primary adrenal insufficiency while they are very rare in secondary adrenal insufficiency. Striae are characterized by linear smooth bands of atrophic appearing skin. They are mostly associated with obesity, pregnancy, hypercortisolism/Cushing syndrome. Striae a...

Introduction: Autoimmune thyroiditis (AIT), also called Hashimoto thyroiditis or chronic lymphocytic thyroiditis is characterized by destruction of the thyroid gland involving apoptosis of thyroid epithelial cells. It usually presents as euthyroidism or subclinically hypothyroidism, rarely as overt hypothyroidism. The cause of Hashimoto’s thyroiditis is thought to be a combination of genetic susceptibility and environmental factors. Bisphenol A (BPA), an endocrine-disrupt...

Extraadrenal perirenal myelolipom has been reported since 1980. In recent years, it has been reported at an increasing rate in different sites of the body ranging from the nasal cavity, mediastinum to presacral, paravesical region. However, it was the first reported case that perirenal multiple myelolipomas, each myelolipomas was about 5 cm in diameter, in associated with cortisol hypersecretion. A patient was an emigrant. She was followed in her country and was prescribed ket...