Endocrine Abstracts

İntroduction: Gitelman syndrome is characterized with hypokalemia, hypomagnesemia, hypocalciuria, metabolic alkalosis and neurological symptoms like muscle weakness. The association of GS and type 1 diabetes is rare, only described in a few case reports. We report a patient with unusual combination of Gitelman syndrome, Type 1 Diabetes Mellitus whose presentation was erytrocytosis.Case: A 26-year old male was diagnosed as Gitelman’s syndrome 5...

Introduction and aims: Subacute thyroiditis (ST) is a spontaneous remitting inflammatory disease of thyroid gland. Although there is no clear evidence for its specific etiology, multiple factors may responsible for this inflammatory reaction. Mean platelet volume (MPV) is a new important inflammatory marker that indicates disease activity. Aim of this study is to evaluate MPV value in patients with subacute thyroiditis.Materials and methods: Thirty-one p...

Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron and sodium and water homeostasis. Patients with hypothryoidism can have clinically important reductions in glomerular filtration rate (GFR). 41 patients (mean age 31.5±11 years) newly diagnosed as Hashimoto thyroiditis with presence of high thyroid autoantibodies with gland heterogenity in ultrasound and a...

Pentraxin 3 (PTX3) is produced from several cell types in case of inflammation. PTX3 has been investigated in several autoimmune diseases. As Hashimoto disease is an autoimmune disease of thyroid, we investigated the role of PTX3 levels in patients with Hashimoto disease.Objective: The aim of this study was to investigate the relationship between PTX3 and autoimmune thyroiditis.Methods: The study subjects were classified as four gr...

Aim: Thyroid Stimulating Hormone (TSH) suppression treatment may have a detrimental effect on bone tissue in differentiated thyroid cancer (DTC) patients. The current study aimed to investigate vertebral fracture, bone mineral density measurements, and TSH levels in DTC patients under levothyroxine (LT4) suppression treatment after total thyroidectomy and/or radioiodine ablation therapy in a multicentric setting.Material and Method: This multicentric cro...

Introduction: Sheehan’s sydrome was known varying degrees of hypopituitarism due to postpartum ischemic necrosis by different etiologies. We report two case who are presented with pancytopenia which is unusual and rarely observed an important clinical finding associated with Sheehan’s syndrome.Case 1: A 57-year-old woman has complaints of malaise, fatigue, and dyspnea without lymphadenopatia and hepatosplenomagaly. She had excessive bleeding af...

Smoking is a modifyable risk factor in the incidence of impaired glucose tolerance and type 2 diabetes, but the data concerning the effect of smoking on the course of type 2 diabetes is limited. In this study, we aimed to investigate a possible relationship between smoking and the need of insulin therapy in patients with type 2 diabetes. 470 patients with type 2 diabetes were assessed for smoking habitus, marital and educational status, duration of diabetes, duration of insuli...

Aim: Overt/subclinic hypothyroidism and hyperthyroidism are known to be associated with cardiovascular risks. There have been no studies evaluating the relationship between nodule presence and arterial stiffness in individuals with euthyroid nodular goitre. Our aim in this study is to demonstrate whether nodule presence and nodule stiffness affect arterial stiffness in individuals with euthyroid nodular goitre by using pulse wave analysis (PWA).Materials...

Evaluation of Laboratory Findings of Primary Hyperparathyroidism in Geriatric PatientsBackground: Primary hyperparathyroidism (PHPT) is an endocrine disease characterized by excessive secretion of parathormone (PTH) from one or more parathyroid glands. In recent studies, it has been reported that the PHPT clinic has turned into a largely asymptomatic disease in recent years. There are few studies on the effect of aging on laboratory find...

Introduction: Exosomes are nanoparticles containing bioactive molecules reflecting individual physiological status, regulating metabolism, and repairing damaged tissues. Exosomes are extracellular vesicles with nano-sized features (30-150 nm) involved in cell-to-cell communication and maintaining homeostasis. The function of exosomes is different according to their cargo and they can contain lipids, proteins and nucleic acids. Exosomes originating from mammalian cells as well ...