Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.11.06 | Calcium, Vitamin D and Bone (1) | ECE2015

Relationship between serum 25-hydroxivitamin D3 and adipose tissue vitamin D receptor gene expression with obesity and type 2 diabetes

Munoz-Garach Araceli , Clemente-Postigo Mercedes , Fernandez-Garcia Diego , Cardona-Diaz Fernando , Macias-Gonzalez Manuel , Tinahones-Madueno Francisco

Introduction: 25-hydroxyvitamin D (25(OH)D3) deficiency has been associated with diabetes and obesity. However, the mechanisms underlying these relationships are not completely understood. Vitamin D receptor (VDR) is expressed in adipose tissue; it has been reported a higher expression in obese patients than in lean subjects, suggesting a differential vitamin D dynamics in adipose tissue according to the obesity degree. In addition, 1, 25-dihydroxyvitamin D3 (1,25(OH)2D3) is a...

ea0037ep433 | Diabetes (complications & therapy) | ECE2015

Association between cardiovascular disease and microvascular complications in diabetic patients

Miguel Gonzalo Allo , Fernandez Elena Garcia , Rodriguez Juan Carlos Romero , Diaz-Guerra Guillermo Martinez , Carranza Federico Hawkins

Introduction: Diabetes mellitus is a condition on the increase, carrying a high risk of cardiovascular complications. It is, also, well known that diabetes confers a substantial burden of microvascular disease. Previous studies suggest a link between microvascular and macrovascular events in diabetes. However, just a few studies have investigated whether the presence of previous cardiovascular events is associated with microvascular disease in diabetes patients. So, this is th...

ea0037ep683 | Pituitary: basic and neuroendocrinology | ECE2015

The role of tolvaptan in syndrome of inappropriate antidiuretic hormone secretion: clinical outcomes and effect on length of stay

Vazquez Yolanda Lopez , Perez Maria Barragans , Barros Cristina Trigo , Gonzalez Angel Martinez , Garma Javier Lago , Fernandez Concepcion Paramo

Introduction: Hyponatremia is the most common electrolyte imbalance among hospitalised patients. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is considered the most frequent etiology on patients with euvolemic hiponatremia. Conventional treatment includes water restriction and salt tablets with limited efficacy and very slow onset of action in certain patients.Material and methods: Systematic sampling of all SIADH patients treated wit...

ea0037ep1037 | Thyroid (non-cancer) | ECE2015

Thyroidectomy: analysis of 184 cases in a single centre

Gallardo Gema Lopez , Alfonso Francisco Javier Gomez , Fernandez Julia Silva , Manzanares Alvaro Garcia , Gomez Ines Rosa , Iglesias Maria Lopez

Aim: To evaluate whether differences exist in terms of patient, radiological, tumour characteristics and surgical complications between malignant and benign thyroidectomy.Materials and methods: 184 correlatives cases of thyroidectomy during the period from October 2011 to October 2013 are analysed. Patient, ultrasound, tumour and complication characteristics are compared. Categorical data are reported as percentages. Characteristics between the two group...

ea0035p91 | Bone and Osteoporosis | ECE2014

Usefulness of serum sclerostin as a diagnostic marker of osteoporosis in a cohort of spanish postmenopausal women

Luque-Fernandez Ines , Garcia-Martin Antonia , Reyes-Garcia Rebeca , Morales-Santana Sonia , Garcia-Fontana Beatriz , Munoz-Torres Manuel

Introduction: Sclerostin, produced by osteocytes, is a potent inhibitor of Wnt signaling and bone formation. The usefulness of its determination in clinical practice is not well established.Objectives: The aims of this study were to evaluate serum sclerostin levels in a cohort of Spanish posmenopausal women, and to analyze its relationship with bone metabolism.Methods: We measured serum sclerostin in 97 posmenopausal women using EL...

ea0035p376 | Diabetes (epidemiology, pathophysiology) | ECE2014

Prevalence of androgenic deficit in men with metabolic alterations

Roman Miriam Menacho , Fernandez Antonio Becerra , Lopez Gilberto Perez , Vicente Rosa Villar , del Rey Sanchez Jose Manuel

Introduction: The syndrome of late-onset hypogonadism (LOH) is a clinical and biochemical syndrome associated with advancing age male, characterized by typical symptoms and decreased serum concentrations of testosterone, which can affect multiple organ systems and may impair quality of life. The prevalence of LOH syndrome is higher in certain patient groups, obese, diabetic and suffering from erectile dysfunction manifest LOH at higher rates than the general population.<p ...

ea0070ep525 | Thyroid | ECE2020

Continuous enteral feeding in a extremely refractory dumping syndrome

Gonzalez Fernandez Mikel , Elena Lopez Alaminos Maria , Almendra Alvarado Rosas Karol , Serrano Urzaiz Leticia , Trincado Pablo , De Diego Garcia Patricia

Introduction: Dumping syndrome is a phenomenon produced by the alteration of the pyloric sphincter. It occurs in 20% of pyloroplasty or distal gastrectomies. The syndrome is attributed to the rapid emptying of the chyme in the intestine. The osmotic gradient attracts fluid to the intestine, and this releases vasoactive hormones, such as serotonin or vasoactive intestinal polypeptide.Case report: We present a 82-year-old woman with gastric intervention in...

ea0032p145 | Calcium and Vitamin D metabolism | ECE2013

Experience in the treatment of primary hyperparathyroidism with cinacalcet: data after 12 months of treatment

Luque-Fernandez Ines , Garcia-Martin Antonia , Luque-Pazos Alessandra , Sastre-Marcos Julia , Vicente-Delgado Almudena , Marco-Martinez Amparo , Canovas Barbara

Introduction: Cinacalcet is an oral calcimimetic indicated in treatment of primary hyperparathyroidism if patients do not accept surgery, do not carry out the surgical criteria, there is failure of previous surgery or serious comorbidity that makes surgery impossible.Methods: Descriptive study that included 20 patients with primary hyperparathyroidism who had complete at least 12 months of treatment with cinacalcet for different reasons (eight patients r...

ea0032p382 | Diabetes | ECE2013

Assessment of pre-pregnancy BMI in patients with gestational diabetes

Segura-Galindo Amparo , Fernandez-Alonso Ana Maria , Moreno-Ruiz Inmaculada , Sebastian-Ibanez Virginia , Canizo-Gomez Francisco Javier del

Objective: Relationship between pre-pregnancy BMI (PPBMI) in gestational diabetic (GD) patients, and age, country of origin, family history of type 2 diabetes mellitus (T2DM), GD history, and BMI after pregnancy.Methods: Transversal, descriptive study of 259 consecutive pregnant with confirmed DG. Analysis were based on Fisher’s exact test and Student’s t-test. A P<0.05 was significant (SPSS 19.0).Re...

ea0032p489 | Diabetes | ECE2013

Analysis of the newly diagnosed diabetic patients, one year and five years of evolution, C-peptide, autoinmunity, treatment and metabolic control

Dominguez-Lopez Marta , Fernandez-Arias David , Gonzalez-Molero Inmaculada , Colomo Natalia , Adana Marisol Ruiz de , Soriguer Federico

Objective: We retrospectively analyzed patients with type 1 diabetes onset, attended during the years 2005 and 2006 on the specific query of type 1 DM debut of a tertiary hospital, with initial treatment assessment, at 1 and 5 years evolution.Results: Patients were treated for newly diagnosed DM 1, 25 patients (72% male, 28% female) mean age 23.2 years (14–36), mean BMI: 23.18 (18–33.8%).The clinical presentation included: 88.24% presented with...