Endocrine Abstracts

Background: Hyperprolactinemia is frequently reported with polycystic ovary syndrome (PCOS). However, there is a controversy whether they share a common mechanism or have cause–result relationship or just are coincidental. The objective of the present study was to identify the cause of hyperprolactinemia in patients with PCOS.Methods: We retrospectively evaluated our outpatient admission records for PCOS, hirsutism, oligomenorrhea, or secondary amen...

Objective: Distant metastases from papillary thyroid carcinoma (PTC) are relatively rare and may be associated with a poor prognosis. Herein, we describe a case report with adrenal and lung metastasis of follicular variant of PTC in the context of the review of the literature.Case Report: A 52-year-old male presented with complaints of swelling of his neck and cough. He had been diagnosed with multinodular goiter, obesity, pre-diabetes, and hypogonadism....

Introduction and aim: Overt thyroid dysfunction is well recognized to affect weight, but the influence of minor perturbations of thyroid function remains unclear. There is ongoing debate regarding the influence of minor changes in thyroid hormones status within the normal range and BMI. The aim of this study was to investigate the association between thyroid function within normal ranges and obesity via BMI and body compositions analyzed by bioelectrical impedance.<p class...

Aim: Sheehan‘s syndrome (SS) remains a frequent cause of hypopituitarism in undeveloped and developing countries, but due to improvements in obstetric care, it is rare in developed countries. We aimed to share the results of a retrospective study analyzing the demographic, clinical, imaging, and hormonal characteristics of a large group of patients with SS, and also increase awareness of this syndrome especially in developed countries.Methods: The m...

Objective: The frequency of differentiated thyroid cancer in the Graves’ disease are controversial. The aim of this study was to evaluate the frequency of thyroid cancers in patients operated because of Graves’ disease.Subjects and methods: Sixty-six patients in whom thyroidectomy was performed because of Graves’ disease between 2001 and 2012 were evaluated retrospectively. Patients who had received radioactive iodine treatment and externa...

Introduction: Parathormone (PTH) is one of the major regulator of the bone and mineral metabolism. Elevated PTH levels in patients with primary and secondary hyperparathyroidism is thought to have negative effects on the cardiovascular system. In our study, we aimed to investigate a possible relationship between plasma PTH levels and coronary atherosclerosis.Methods: Fourty-two men and 35 women, a total of 77 patients were included the study who admitted...

Primary hyperparathyroidism is a condition related with cardiovascular mortality and morbidity. Aim of this study is to investigate whether there is a difference between healthy controls, hypercalcemic patients with surgical decision and normocalcemic primary hyperparathyroidism patients for parameters like metabolic cardiovascular risk factors, carotis intima media thickness and pulse wave velocity and if there is a difference at patients with surgical decision 6 months after...

Introduction: The cases of paragangliomas (PGLs) mimicking thyroid nodules were also reported in literature rarely. We will present a case of PGL (a carotid body tumor) that we initially evaluated as a thyroid nodule, and then diagnosed as a PGL.Case report: A 74-year-old woman was admitted due to a mass in the right side of neck growing rapidly within the last 1 month. Physical examination revealed a hard and painless mass with smooth surface, extending...

Context: Irisin, a newly discovered hormone, is secreted by skeletal muscles into circulation. It is proposed to regulate energy homeostasis and hold therapeutic potential in diabetes and obesity.Objective: We aimed to investigate the association of irisin and uncoupling protein 1 (UCP1) with gestational diabetes mellitus (GDM).Design and Setting: This was a cross-sectional study conducted in a university hospital.<p class="abs...

Introduction: The most common cause of diabetes insipidus is idiopathic. However, it may be also seen after metastasis to hypothalamic–pituitary region.Case: Fifty year old female patient with breast cancer was referred to our clinic with complaints of polyuria and polydipsia. Two years ago, she had diagnosed and after surgery, she has taken three cycles of cyclophosphamide+adriamycin+5-flurourasil than three cycles dosetaxel and finally seventeen c...