Endocrine Abstracts

Introduction: Strokes are common diabetes macrovascular complications. A good control of cardiovascular risk factors such as glycemic control has been proven to reduce the risk of its appearance. Aim: Describe diabetes prevalence in patients admitted to hospital because of a stroke, as well as their treatment and metabolic control.Patients and methods: Observational retrospective study of patients admitted to the Neurology section because of a s...

Introduction: Flash glucose monitoring (FGM) allows non-invasive glucose level assessment. Studies have shown that patients using FGM test their glucose levels more often than those who use traditional blood glucose testing. Given that a higher rate of glucose testing has showed to improve glycemic control our objective was to describe the change in the glycemic control and time in euglycemic range in patients with FGM and the effect of the number of scans in this control....

Introduction: Non-functioning pituitary adenomas (NFPAs) represent the most common pituitary tumour. They usually appear in the middle age of life, without differences between genders. Mass growth produces the first symptoms so the diagnosis is usually late. Surgery is the first-line treatment with variable success (19-83%). The objective of this study is to evaluate the symptoms, diagnosis, treatment and final state of patients with NFPAs.Methods: Obser...

Introduction: The duration of hypercortisolism in Cushing’s disease (CD) appears to be inversely related to the reversibility of complications, which in turn increase mortality. This makes it necessary to identify medical therapies capable of normalizing cortisol overproduction before transsphenoidal surgery. The aim of this study was to determine if the clinical data of patients with CD before surgery allow predicting the presence and/or abundance of somatostatin (ssts) ...

Background: The short-term follow-up of patients with differentiated thyroid cancer (DTC) after the initial treatment is based on the measurement of stimulated thyroglobulin (s-Tg) and the use of diagnostic whole body scan (WBS).Objective: To evaluate the clinical utility of WBS performed at 6–12 months after thyroidectomy. Examine the correlation between s-Tg and results of WBS.Methods: We retrospectively evaluated all patien...

Neuroendocrine tumors (NETs) are uncommon neoplasms with increasing incidence and limited therapeutic options, wherein identification of new diagnostic/prognostic/therapeutic biomarkers is urgently required. Alterations in somatostatin (SST)/cortistatin (CORT) and ghrelin systems have been associated to development/progression of several cancers. Thus, we evaluated expression levels of SST/CORT/ghrelin system components in gastroenteropancreatic-neuroendocrine tumors (GEP-NETs...

Introduction: Due to the widespread use of imaging studies performed in hospitalised patients for other indications, adrenal incidentalomas (AI) are frequent findings in the everyday clinical practice. The objective of this research is to describe the prevalence of hormonally active and malignant AI.Patients and methods: Observational retrospective study of a cohort of patients who consulted in the Endocrinology service between 2005 and 2015 because of a...

Objective: The aim of this study was to assess the diagnostic accuracy of BIPSS with desmopressin stimulation in the differential diagnosis of ACTH-dependent Cushing’s syndrome.Patients and methods: Retrospective study of patients studied to our hospital for diagnosis of ACTH-dependent Cushing’s syndrome (2000–2015). The histopathological results in patients who underwent a surgical procedure was considered the reference for statistical st...

Introduction: The Bethesda System classifies suspicious thyroid nodules or those with a large size after fine-needle aspiration (FNA) depending on the risk of malignancy through its cytology study. Bethesda category 3 (B3) implies atypia of uncertain significance or follicular lesion of undetermined significance. Objectives: To determine the final diagnosis of category B3 nodules and the number of cases in which a second or third FNA results in a conclusive category (B2, B4, B...

Background: The management of patients with differentiated thyroid cancer (DTC) has been changing in recent years and aggressiveness of treatment depends on the risk of persistent or recurrent disease.Objective: The aim of this study was to assess the efficacy of low doses of Radioactive Iodine (RAI;131I) therapy in patients with DTC.Methods: We retrospectively evaluated all patients who were diagnosed with DTC (n</e...