Endocrine Abstracts

AimTo examine and compare the anxiety level and stress perception of acromegaly patients with controlled and active disease in the COVID-19 pandemic.Material and Method49 (23 females/26 males) patients admitted to the outpatient clinic during the first month after the pandemic period were recruited in this cross-sectional study. State-Trait Anxiety Inventory (S-Anxiety for state scale, T-Anxiety for trait sca...

AimsWe aimed to reveal the impacts of dapagliflozin, a sodium glucose transporter inhibitor (SGLT2i), on the body weight and body composition, cardiovascular risk indexes, and carotis intima-media thickness (CIMT).MethodsBody weights, body compositions measured by means of bioelectrical impedance, and CIMT in the baseline, the 12th, and the 24th week of 42 patients with type-2 diabetes mellitus receiving SGLT...

PurposeThyroid hormones are known to have an essential role in the regulation of energy homeostasis and glucose metabolism. Considering to literature data, variations of thyroid hormones within normal ranges change in obesity and type 2 diabetes mellitus (T2DM) in opposite ways. This study aims to evaluate thyroid hormone levels and fT3/fT4 ratio in different glucose metabolism statuses of euthyroid patients with obesity.Methods</p...

Background: The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis has effects on renal growth and electrolyte regulation. However, data on adverse renal comorbidities such as renal cysts and stones in acromegaly is scarce. The current study aimed to investigate the prevalence of radiologically detectable renal comorbidities and possible related factors in the acromegaly population.Methods: A total of 125 patients with acromegaly (46.4&pm;11.6...

Background: Papillary thyroid microcarcinoma (PTMC) is a papillary thyroid cancer (PTC) type with a maximum diameter of ≤ 10 mm. Generally, PTMCs have good prognosis and low mortality risk. However, there are cases of PTMCs showing more biologically aggressive characteristics, such as lymph node (LN) involvement and distant metastasis.Objectives: Reveal the factors affecting the prognosis and aggressiveness of PTMCs.Methods: ...

Introduction: Papillary thyroid microcarcinomas (PTMC) are usually detected incidentally. They occur as a result of histological/microscopic examination of a thyroid removed especially for nodular goiter. Generally, the prognosis is good. However, it has been reported that lymph node (LN) metastasis is more common especially in PTMCs with tumor size > 5mm. In this study, it was aimed to show the effect of tumor size on prognosis by comparing clinicopathological data in pat...

Objective: The present study aimed to evaluate thyroid stimulating hormone (TSH) levels and anti-thyroid peroxidase antibodies (anti-TPOab) in euthyroid subjects with metabolic syndrome (MetS) and to compare them with healthy subjects without MetS.Design: Study included 173 subjects consisted of 96 subjects with MetS and 77 healthy controls. Gender, age, body mass index (BMI), waist circumfrence (WC), and detailed medical history of all participants were...

Brown tumor is a non-neoplastic lesion which resulting from abnormal bone metabolism caused by hyperparathyroidism. We report a rare case of peripheral brown tumor related with primary hyperparathyroidism which simulating a peripheral giant cell granuloma of the jaws.Introduction: PHPT occurs in a setting of excessive parathyroid hormone (PTH) secretion which resulting in hypercalcemia.Case report: A 50-year-old man was admitted to...

Introduction: Primary hyperparathyroidism (PHPT) is a disease associated with a decrease in bone mineral density (BMD), especially in cortical bones such as distal radius. Therefore, the BMD measurement of forearm is valuable in the detection of cortical bone loss by PHPT. However, forearm measurement is not routinely recommended for the diagnosis of osteoporosis in PHPT. In this study, we aimed to evaluate the importance and priority of forearm BMD measurement in PHPT.<p ...

Objective: The specificity and cellular origin of the SSRS findings in CN, HN, PC and GD is currently unclear and partially contradicts the well defined action of somatostatin on thyroid cell signaling. Therefore, we systematically evaluated SSTR2 expression in benign cold (CN) and hot thyroid nodules (HN), papillary carcinomas (PCs) and Graves’ disease (GD) in comparison with intraindividual control surrounding tissues (ST) by means of immunohistochemistry.<p class="...