Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep180 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Vitamin B12 status and maternal-fetal outcomes among women with gestational diabetes

Gutu Olga , Natércia Candeias , António Afonso , Silva-Nunes Jose

IntroductionVitamin B12 (vB12) deficiency has been associated with a plethora of hematologic, neurologic and metabolic abnormalities. In pregnant women, several studies have demonstrated an association with a greater maternal body mass index (BMI), maternal and offspring insulin resistance, gestational diabetes mellitus (GDM) and even later type 2 diabetes.Aim of the studyEvaluation of maternal and fetal outc...

ea0070aep393 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

2-hr vs 1-hr glucose tolerance testing for pre-DM diagnosis, among HIV-infected patients

Guerreiro Vanessa , Cristina Santos Ana , Serrão Rosário , Sarmento António , Carvalho Davide , Freitas Paula

Introduction: Plasma glucose concentration at 1h(1hPG) during an oral glucose tolerance test(OGTT) may be a better predictor of future diabetes mellitus(DM) than 2-h post load glucose concentration(2hPG). HIV-infected individuals may have differential risk of DM compared to the general population, and the optimal diagnosis algorithm for DM in HIV-infected persons remain unclear. We evaluated the agreement of the methods 1 hPG vs 2 hPG) for the diagnosis of pre-D...

ea0014p338 | (1) | ECE2007

Prevalence of thyroid antibodies in gestational diabetes mellitus

Ruas Luísa , Paiva Sandra , Campos Maria , Marta Elvira , Lobo António , Cravo Annette , Carvalheiro Manuela

Background: Pregnancy alters the natural history of autoimmune thyroid disorders. The incidence rate of positive thyroid antibodies (T-abs +) in asymptomatic women during pregnancy has been reported to be between 6 and 19.6%.Aim: To determine the prevalence of thyroid antibodies (T-abs) in Gestational Diabetes Mellitus (GDM).Subjects & Method: In 408 women, at the time of diagnose of GDM, TSH, free thyroxine, free tri-iodothyro...

ea0073aep56 | Adrenal and Cardiovascular Endocrinology | ECE2021

Paraganglioma in pregnancy: The need for a multidisciplinary approach

Elvas Ana Rita , Bárbara Araújo , Couto Joana , Martins Raquel G. , Paiva Sandra , António Lobo , Santos Fernando , Paiva Isabel , Rodrigues Fernando

IntroductionParagangliomas (PGL) of the urinary bladder are an extremely rare entity. During pregnancy, PGL can carry higher risk of foetal and maternal mortality, which can be significantly reduced when the diagnosis is made antepartum and adequate multidisciplinary management and surveillance is started. However, despite clinical stability, delivery complications rates are still higher than in the general obstetric population.Cas...

ea0070aep174 | Bone and Calcium | ECE2020

Colour doppler ultrasound: Preoperative location of parathyroid adenomas in primary hyperparathyroidism

Amaral Sara , Rego Teresa , Vasques Miguel , Gutu Olga , Cláudia Martins Ana , Palha Ana , Sabino Teresa , Cortez Luísa , Afonso António , Fonseca Fernando , Carrilho Nuno , Mário Coutinho José , Tavares Paula , Agapito Ana

Introduction: Parathyroid adenoma is the most frequent cause of primary hyperparathyroidism (PHPT). In recent years minimally invasive surgical techniques have challenged the traditional bilateral neck exploration. There are different imaging techniques for preoperative location of parathyroid adenomas. In this study the authors review the role of Doppler ultrasound focusing on its safety, availability and affordability.Aim: To evaluate the role of Doppl...

ea0073aep199 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Diabetes mellitus and COVID-19 – The bidirectional impact

Inês Manique , Alexandra Abegão Matias , Rego Teresa , Sabino Teresa , Bouca Bruno , Ana Cláudia Martins , Mihon Claudia , António Panarra , José Silva-Nunes

IntroductionSARS-CoV2 infection can worsen glycemic control regardless of history of Diabetes mellitus (DM) and may precipitate new-onset diabetes (NOD). DM is also a risk factor for a greater severity of COVID-19. At-admission hyperglycemia (AH) is a known predictor of critical illness in other diseases.AimsAssess the impact of AH, regardless of the presence of DM, on the severity of COVID-19 inpatients....

ea0073aep246 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Risk factors associated with diabetic foot amputation among patients hospitalized for diabetic foot ulcer in a public hospital

Gutu Olga , Vasques Miguel , Inês Manique , Amaral Sara , Bruno Bouça , Prokop Joanna , Ana Cláudia Martins , António Afonso , José Neves , Silva-Nunes Jose

IntroductionDiabetic foot is one of the most devastating of chronic complications of diabetes mellitus (DM) and is responsible for about 25% of hospitalizations. Worldwide, the diabetic foot represents the main cause of non-traumatic lower limb amputation.Aim of the studyIdentification of risk factors for foot amputation among in patients hospitalized for diabetic foot in a tertiary public hospital in Portuga...

ea0073aep521 | Pituitary and Neuroendocrinology | ECE2021

Outcomes and complications of endoscopic pituitary surgery: A single-center study

Taibo Rocio Villar , Alicia Santamaría Nieto , Paula Andújar Plata , Antía Fernández Pombo , María Gemma Rodríguez Carnero , Ignacio Bernabeu Morón

ObjectivesTo present the results of our series of endoscopic surgery of PA, performed in a third level hospital by an experienced team.MethodsRetrospective review of PA undergoing endoscopic surgery between 2011 – 2018 in our institution. Clinical variables and radiological characteristics and outcomes were collected at diagnosis, before surgery and for an average of 4.8 years of postoperative follow-up....

ea0070aep758 | Pituitary and Neuroendocrinology | ECE2020

Silent corticotroph adenoma: Experience with six cases

Serra Soler Guillermo , Antich Barceló Carlos , Bodoque Cubas Javier , García Fernández Honorato , Mas Bonet Antonio , Antón Valentí Ester , Mena Ribas Elena , Tofé Povedano Santiago , Argüelles Jiménez Iñaki , Pereg Macazaga Vicente

Introduction: Silent corticotroph adenomas (SCA) represent a subtype of pituitary adenomas whose prevalence is 3% of pituitary adenomas. They are characterized by having a positive immunohistochemistry to corticotropin (ACTH) without clinical or biochemical data of hypercortisolism. The diagnosis is a challenge since they are considered as ANF, and it is with the pathology report after surgery when they are classified as SCA. They have more aggressive behavior and recur more t...

ea0070aep863 | Thyroid | ECE2020

Retrospective incidence of NIFTP. A large multicentre Iberic study of over 3000 neoplasms

Paja Miguel , Rosa Bella M. , Iglesias Carmela , Zafón Carles , Cameselle Jose M.l , Carnero Gemma , Póvoa Antónia , Ugalde Aitziber , Anda Emma , Fernández-Seara Pilar , Sánchez-Gómez Nancy M. , Quiceno Hernán , García-Pascual Lluis , González Clarisa , Blanco Concepción , Gómez de la Riva Inés , Capel Ismael , Mancha Isabel , Gallego Helena , Maravall Javier , Roselló Esther , Alcázar Victoria , Chao Montserrat , Lázaro Antonia , Lopez-Agulló Susana , Echeverría Saioa , Joaquín Paricio J. , Sanz Javier , Messeguer Pascual , Castaño Ángel

The newly created NIFTP category (non-invasive follicular thyroid neoplasm with papillary-like nuclear features) has had a notorious impact in the management of thyroid neoplasms. Its incidence appears to be higher in western countries than Asiatic, but there are few studies including more than one institution.Objectives: To evaluate retrospectively the incidence of NITFP in a multicentre study in two adjacent countries as well as to compare th...