Endocrine Abstracts

IntroductionVitamin B12 (vB12) deficiency has been associated with a plethora of hematologic, neurologic and metabolic abnormalities. In pregnant women, several studies have demonstrated an association with a greater maternal body mass index (BMI), maternal and offspring insulin resistance, gestational diabetes mellitus (GDM) and even later type 2 diabetes.Aim of the studyEvaluation of maternal and fetal outc...

Introduction: Plasma glucose concentration at 1h(1hPG) during an oral glucose tolerance test(OGTT) may be a better predictor of future diabetes mellitus(DM) than 2-h post load glucose concentration(2hPG). HIV-infected individuals may have differential risk of DM compared to the general population, and the optimal diagnosis algorithm for DM in HIV-infected persons remain unclear. We evaluated the agreement of the methods 1 hPG vs 2 hPG) for the diagnosis of pre-D...

Background: Pregnancy alters the natural history of autoimmune thyroid disorders. The incidence rate of positive thyroid antibodies (T-abs +) in asymptomatic women during pregnancy has been reported to be between 6 and 19.6%.Aim: To determine the prevalence of thyroid antibodies (T-abs) in Gestational Diabetes Mellitus (GDM).Subjects & Method: In 408 women, at the time of diagnose of GDM, TSH, free thyroxine, free tri-iodothyro...

IntroductionParagangliomas (PGL) of the urinary bladder are an extremely rare entity. During pregnancy, PGL can carry higher risk of foetal and maternal mortality, which can be significantly reduced when the diagnosis is made antepartum and adequate multidisciplinary management and surveillance is started. However, despite clinical stability, delivery complications rates are still higher than in the general obstetric population.Cas...

Introduction: Parathyroid adenoma is the most frequent cause of primary hyperparathyroidism (PHPT). In recent years minimally invasive surgical techniques have challenged the traditional bilateral neck exploration. There are different imaging techniques for preoperative location of parathyroid adenomas. In this study the authors review the role of Doppler ultrasound focusing on its safety, availability and affordability.Aim: To evaluate the role of Doppl...

IntroductionSARS-CoV2 infection can worsen glycemic control regardless of history of Diabetes mellitus (DM) and may precipitate new-onset diabetes (NOD). DM is also a risk factor for a greater severity of COVID-19. At-admission hyperglycemia (AH) is a known predictor of critical illness in other diseases.AimsAssess the impact of AH, regardless of the presence of DM, on the severity of COVID-19 inpatients....

IntroductionDiabetic foot is one of the most devastating of chronic complications of diabetes mellitus (DM) and is responsible for about 25% of hospitalizations. Worldwide, the diabetic foot represents the main cause of non-traumatic lower limb amputation.Aim of the studyIdentification of risk factors for foot amputation among in patients hospitalized for diabetic foot in a tertiary public hospital in Portuga...

ObjectivesTo present the results of our series of endoscopic surgery of PA, performed in a third level hospital by an experienced team.MethodsRetrospective review of PA undergoing endoscopic surgery between 2011 – 2018 in our institution. Clinical variables and radiological characteristics and outcomes were collected at diagnosis, before surgery and for an average of 4.8 years of postoperative follow-up....

Introduction: Silent corticotroph adenomas (SCA) represent a subtype of pituitary adenomas whose prevalence is 3% of pituitary adenomas. They are characterized by having a positive immunohistochemistry to corticotropin (ACTH) without clinical or biochemical data of hypercortisolism. The diagnosis is a challenge since they are considered as ANF, and it is with the pathology report after surgery when they are classified as SCA. They have more aggressive behavior and recur more t...

The newly created NIFTP category (non-invasive follicular thyroid neoplasm with papillary-like nuclear features) has had a notorious impact in the management of thyroid neoplasms. Its incidence appears to be higher in western countries than Asiatic, but there are few studies including more than one institution.Objectives: To evaluate retrospectively the incidence of NITFP in a multicentre study in two adjacent countries as well as to compare th...