Searchable abstracts of presentations at key conferences in endocrinology

ea0056p275 | Endocrine Disruptors | ECE2018

Role of Pro-inflammatory cytokines in Primary Hyperparathyroidism: A Prospective Study

Venkateshwara Reddy M , Bhargav PRK , Ramesh B , Rajesh B , Chakrapani B , Vighnesh D , Rajkiran Reddy A , Vimala Devi N

Introduction: Primary Hyperparathyroidism (PHPT) is a frequent endocrine disease which requires surgical excision for definitive cure. Apart from genetic role in its pathogenesis, there are conflicting reports about role of immunomodulation in literature. In this context, we set out study the role of Pro- inflammatory cytokines in PHPT in South Indian population.Material and methods: This prospective case-control study was conducted on surgically managed...

ea0056p903 | Endocrine Disruptors | ECE2018

Correlational evaluation of inflammatory biomarkers in polycystic ovarian disease: a case control study

Gayathri G , Rajesh B , Ramesh B , Vignesh D , Venkateshwara Reddy M , Rajkiran Reddy B , Chakrapani B , Bhargav PRK

Introduction: Contrary to the high prevalence of polycystic ovarian syndrome (PCOS) amongst reproductive age group women, there is disproportionate uncertainity over its etiopathogenesis. Substantial evidence suggests immunological-inflammatory role in causing this endocrine disorder. In this context, we set out study the role of inflammatory biomarkers in PCOS.Material and methods: This prospective case-control study was conducted on PCOS patients diagn...

ea0056p1124 | Thyroid cancer | ECE2018

Association of pro-inflammatory biomarkers in papillary thyroid cancer: a prospective study

Vignesh D , Ramesh B , Rajesh B , Venkateshwar Reddy M , Gayathri G , Rajkiran Reddy B , Chakrapani B , Bhargav PRK

Introduction: Papillary thyroid carcinoma (PTC) is the commonest endocrine malignancy. Apart from genetic role in its pathogenesis, autoimmunity has been implicated in certain papers. But, reports have been tripolar ranging from causative, protective and neutral role of immunomodulation. In this context, we set out study the role of Pro- inflammatory cytokines in PTC in South Indian population.Material and methods: This prospective case-control study was...

ea0056ep91 | Environment, Society and Governance | ECE2018

Selfie driven thyroid disease leads (SET): a study on a unique phenomenon from Surgical Endocrinology Department

Panchangam Ramakanth Bhargav , B Chakrapani , B Ramesh , B Rajesh , M Venkateshwara Reddy , D Vignesh , N Vimala Devi , G Gayathri

Introduction: Taking a photograph of self alone or with a group called Selfie, has become modern day rage with spurt in smart phone technology. It has catapulted from a hobby in to psychiatric ailment, especially amongst teens and young adults. Though, it is considered as a psychiatric aberration keeping them aloof from social interactions, we observed an inadvertent advantage in this habit. In this context, we present some intriguing findings through this study.<p class="...

ea0063p75 | Calcium and Bone 1 | ECE2019

Clinical significance of parathyroid incidentalomas during thyroidectomy: a South Indian experience

Panchangam Ramakanth Bhargav , B Chakrapani , M Sabaretnam

Background: Often parathyroid indicentalomas (PI) in the form macroscopically enlarged single or multiple parathyroid glands are encountered during surgical thyroidectomy. The reported incidence in literature is variable (0.4–4.5%), but we feel its underreported compared to its frequency, as only less than 500 cases were reported thus far. Another enigma about PI is their clinical significance and natural history. In this context, we analysed our own experience and tried ...

ea0063p355 | Thyroid 1 | ECE2019

An ununsual thyroid cause for Pyrexia of unknown origin (PUO)

Panchangam Ramakanth Bhargav , Chakrapani B , Sabaretnam M , Ramesh B , Rajesh B

Introduction: Granulomatous thyroiditis (GT) is one of the various types of autoimmune thyroiditis. It usually occurs in women of reproductive age in perigestational period. Clinical picture in is predominantly painful goiter with radiating pain to ears with low grade fever lasting for few days, sometimes associated with mild hyper or hypothyroidism. The treatment is symptomatic and supportive with no curative option. There are meagre anecdotal reports of thyroidectomy role fo...

ea0063p632 | Interdisciplinary Endocrinology 1 | ECE2019

Alleviation of Autoimmune phenomena in Hashimoto’s thyroiditis after Thyroidectomy: Is this an additional surgical indication?

Panchangam Ramakanth Bhargav , Sabaretnam M , Chakrapani B , Ramesh B , Rajesh B

Introduction: Hashimoto’s thyroiditis (HT) is one of the commonest endocrine disorder. Often, HT is associated with a plethora of autoimmune co-morbidities (AIC) such as vitiligo, arthitides, pernicious anaemia, skin allergy, thrombocytopenia, addison’s disease, type 1 diabetes, celiac disease, eosinophilia etc., The etiology of these AIC in HT is enigmatically idiopathic and hypothesized to be autoimmune in origin. Many studies suggests that thyroid specific antibod...

ea0070ep439 | Thyroid | ECE2020

Next generation sequencing of 12 gene panel in differentiated thyroid cancer

Bangaraiahgari Ramesh , Bhargav Panchangam Ramakanth , B Chakrapani , Mayilvaganan Sabaretnam , B Rajesh , Md Rafi , G Rakshith , Akshaya Ramesh D Lakshmi

Introduction: Next-generation sequencing (NGS) in thyroid cancer allows for high-throughput sequencing analysis of various genetic alterations and provides a useful information of tumor biology. NGS Studies on follicular differentiated thyroid cancer have been scanty from Indian subcontinent. In this context, we set out study the prevalence of a genetic panel wide somatic mutations in thyroid cancer.Material and Methods: This prospective study was conduc...

ea0056p208 | Calcium &amp; Vitamin D metabolism | ECE2018

A Curious phenomenon of Post radioiodine therapy induced hypocalcemia in Graves’ disease: Case series

Panchangam Ramakanth Bhargav , Ramesh B , Rajesh B , Vimaladevi N , Rajkiran Reddy B , Venkateshwara Reddy M , Vignesh D , Chakrapani B

Introduction: Graves’ disease (GD) is often treated with radioiodine therapy for cure. While, post external irradiation and post-radioiodine therapy (RAI) induced hyperparathyroidism after many years of latency is a well known phenomenon, there are only anectodal reports of post-radioiodine hypocalcemia. The factors contributing to this are poorly understood. In this context, we evaluated our own series to look deeper in to this issue.Material and m...

ea0056p528 | Nuclear receptors and Signal transduction | ECE2018

Genotype- Phenotype correlations of TNF-α, IL-6 and Leptin receptor gene polymorphisms in Poly cystic ovarian syndrome

B Rajesh , B Ramesh , G Gayathri , M Venkateshwara Reddy , D Vighnesh , B Rajkiran Reddy , B Chakrapani , PRK Bhargav

Introduction: Tumor necrosis factor alpha (TNF-α) and Interleukin-6 (IL-6) are potent immunomodulators and proinflammatory cytokines displaying varied functions. Apart from monocytes/macrophages, they are also produced by the cells in female reproductive tract. Polycystic ovarian syndrome (PCOS) is one of the commonest endocrine disorder amongst women of reproductive age group. Several polymorphisms in the promoter region of the gene TNF-α, IL-6 and Leptin receptors ...