Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep400 | Diabetes (complications & therapy) | ECE2015

Efficacy of sitagliptin added on to intensive insulin therapy in type 2 diabetic patients

Taskiran Bengur , Cansu Guven Baris

Aim: Despite multiple dose injections some patients still fail achieving HbA1c target. We aimed to evaluate the effect of sitagliptin add on therapy to multiple dose insulin injections.Method: Data of 47 (seven males and 40 females) type 2 diabetic patients who had HbA1c over 7% were retrospectively evaluated. They were already treated with premix lispro or aspart insulin (n=28), glargine plus premeal regular or aspart or lispro insulin (n</...

ea0056p1052 | Thyroid (non-cancer) | ECE2018

Evaluation of 32 patients with subacute thyroiditis

Cansu Guven Baris , Taskiran Bengur

Aim: Thyrotoxicosis is a clinical status related to increased thyroid hormones. It is caused by either hyperfunctioning thyroid tissue or destruction of thyroid. Subacute thyroiditis, also known as De Quervain or granulomatous thyroiditis, is an acute inflammatory disease of thyroid causing thyrotoxicosis. Clinical and laboratory features vary according to the course of disease. In this study, we aimed to study clinical and laboratory features of the patients who were referred...

ea0049ep244 | Bone &amp; Osteoporosis | ECE2017

Neutrophil lymphocyte ratio in 6 month teriparatide therapy of osteoporosis

Taskiran Bengur , Yorulmaz Goknur , Cansu Guven Baris , Akalin Aysen

Aim: Low BMD and atherosclerosis may share similar underlying biological mechanisms including higher serum phosphate and inflammation. Neutrophil-lymphocyte ratio (NLR) as a simple marker of inflammation. There are scarce data indicating improved atherosclerosis and cardiovascular events with biphosphonate and teriparatide therapy. We aimed to evaluate NLR before and after 6 months of teriparatide therapy in patients with severe established osteoporosis....

ea0049ep1375 | Thyroid (non-cancer) | ECE2017

Association of preoperative neutrophil lymphocyte ratio and platelet lymphocyte ratio with clinical features of differentiated thyroid cancer

Taskiran Bengur , Cansu Guven Baris , Yorulmaz Goknur , Mutluay Ruya

Introduction: Platelets and neutrophils take part in proliferation of cancer cells, angiogenesis, and metastasis. Studies on various cancer types showed relation between prognosis and absolute numbers of neutrophils, lymphocytes, and the ratio in-between (NLR) and platelet/lymphocyte ratio (PLR). We aimed to evaluate NLR and PLR and their relation with features of differentiated thyroid carcinoma (DTC).Materials and methods: Electronic data of 330 patien...

ea0041ep579 | Diabetes therapy | ECE2016

Effect of short term GLP-1 modifying therapy on intima media thickness

Taskiran Bengur , Cansu Guven Baris , Bahadir Eylem , Mutluay Ruya

Atherosclerosis is the major cause of death in type 2 DM. Increased intima media thickness (IMT) denotes subclinical atherosclerosis. Endothelial cells express GLP-1 receptors. There are a few studies regarding the effect of GLP-1 system modifying agents on IMT. Although most of them indicates decreased IMT, the results are contradictory.We aimed to compare the effect of sitagliptin, vildagliptin, and exenatide on IMT measurement in type 2 DM.<p clas...

ea0041ep1165 | Thyroid cancer | ECE2016

An unusual case in endocrinology practice: suture granuloma

Cansu Guven Baris , Taskiran Bengur , Bakar Tulay , Cengiz Betul Peker

Background: Suture granuloma, the rare complication of thyroidectomy, results from use of nonabsorbable suture materials. Despite its typical ultrasound images and benign course, it carries utmost importance in differential diagnosis of lymph nodes, recurrent nodules, and recurrence in case of thyroid cancers.Case report: A 54-year-old female patient, who underwent bilateral thyroidectomy in July 2010, was diagnosed with multinodular goiter and incidenta...

ea0037ep1248 | Clinical Cases–Thyroid/Other | ECE2015

Bullous pemphigoid induced by vildagliptin

Taskiran Bengur , Erdogan Bahattin , Sisman Canan Solak , Cansu Guven Baris

Introduction: Bullous pemphigoid (BP) is an uncommon chronic, autoimmune, and subepidermal disease. It can be associated with drugs, u.v. irradiation, and X-ray therapy. There is a number of reports on bullous pemphigoid (BP) induced by DPP-IV inhibitors (vildagliptin, sitagliptin, saxagliptin). The enzyme DPP-IV degrades glucagon like peptide 1 (GLP-1), which is a potent stimulator of insulin production and secretion. DPP-IV (CD26), present as a cell surface molecule on immun...

ea0037ep752 | Pituitary: clinical | ECE2015

The comparison of echocardiographic parameters, carotid intima thickness, arterial stiffness and plasma soluble CD40 ligand levels in active and inactive acromegalic patients

Cansu Guven Baris , Yilmaz Nusret , Yanikoglu Atakan , Ozdem Sebahat , Yildirim Aytul , Suleymanlar Gultekin , Altunbas Hasan

Introduction: In acromegalic patients, the increased mortality and morbidity are generally due to cardiovascular, metabolic, respiratory and cerebrovascular diseases, so early diagnosis and treatment of cardiovascular lesions may save lives. The aim of this study is to find out the any possible difference in terms of carotid intima media thickness (CIMT), indices of arterial stiffness, soluble CD40 ligand (sCD40L) and some echocardiographic parameters between active and inacti...

ea0035p131 | Calcium and Vitamin D metabolism | ECE2014

Evaluation of biochemical cardiovascular risk factors, carotid intima media thickness, and arterial stiffness before and after surgery in patients with primary hyperparathyroidism

Cansu Guven Baris , Ozdem Sebahat , Suleymanlar Gultekin , Sari Ramazan , BAlcI Mustafa Kemal , Altunbas Hasan Ali

Primary hyperparathyroidism is a condition related with cardiovascular mortality and morbidity. Aim of this study is to investigate whether there is a difference between healthy controls, hypercalcemic patients with surgical decision and normocalcemic primary hyperparathyroidism patients for parameters like metabolic cardiovascular risk factors, carotis intima media thickness and pulse wave velocity and if there is a difference at patients with surgical decision 6 months after...

ea0056gp99 | Diabetes Therapy | ECE2018

Optimal time for measuringglucose level to detect steroid induced hyperglycaemia

Cansu Guven Baris , Cansu Dondu Uskudar , Taskiran Bengur , Bilge Sule Yasar , Bilgin Muzaffer , Korkmaz Cengiz

Purpose: Steroid usage may cause hyperglycaemia in non-diabetic patients. We aimed to detect the onset of hyperglycaemia and the best time for glucose measuring over a short time span (1–5 days) in non-diabetic patients who commenced moderate or high dose steroid therapy.Methods: Electronic data of patients, who were commenced moderate or high dose steroid therapy (15–60 mg prednisolone or equivalent dose methyl prednisolone) due to inflammator...