Endocrine Abstracts

Introduction: Growth hormone deficiency is a rare cause of stunting; its diagnosis is often delayed by severe growth retardation; confirmed by non-response to GH stimulation tests (insulin and glucagon-propranolol test). The absence of early diagnosis and treatment can lead to severe growth retardation. We propose to determine the prevalence of different etiologies of growth hormone deficiency in patients followed for a saturo-weight delay at the Arrazi Hospital, Medical Unive...

Introduction: Neurofibromatosis type 1 (NF1) is the most common autosomal dominant disease. The endocrine manifestations of NF1 are represented by pubertal abnormalities and pheochromocytoma. We report a case.Observation: Mr. G.A, age 28, consulling for a grade 2 HTA evolving for 3 years. The anamnesis notes paroxysmal crises made of Ménard triad. The exam notes a correct blood pressure, 18 coffee latte tasks, lentiginous tasks. Two neurofibromas of...

Introduction: Persistent hypocalcemia after surgery for severe hyperparathyroidism are not uncommon and may be secondary to transient or permanent hypoparathyroidism but may also be due to bone pathology.Observation: Patient of 44 years old was hospitalized for fractures of the pelvis, and shaft of left femur, spontaneous without trauma turned out. Laboratory tests shows severe hypercalcaemia to 156 mg/l, serum phosphorus at 22 mg/l, elevation of PTH to ...

Introducing: Primary hyperparathyroidism (HPT1) is a frequent endocrinopathy. Diagnosed incidentally or in front of a urinary or bone symptomatology, we report a case of primary hyperparathyroidism in the mode of revelation makes the originality “a paralyzing sciatica”.Observation: The patient was 44 years old and was undergoing neurosurgery for chronic low back pain that was resistant to etiological treatment. In view of the persistent and hyp...

Introduction: The HAIR-AN syndrome, which consists of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN), is an underdiagnosed endocrinopathy.Observation: We report the case of Miss A.M., 24 years old, admitted for exploration of hyperandrogenism. Anamnesis: the patient reported polyuropolydipsic syndrome and the notion of weight gain without eating disorders, making a total of 28 kg in 6 months. This period is also marked by th...

Introduction: Kallmann syndrome (KS) is a rare disorder. It is now designated as olfactogenital dysplasia with an association between agenesis of the olfactory bulbs and hypogonadism. The association of KS with a pituitary microadenoma has not been well described in the literature.Case report: It’s a 16-year-old and 6 months, admitted for evaluation of a micropenis, he has as ATCDs an orchidopexy performed at the age of 3 years, infertility in the m...

Systemic lupus erythematosus is a serious autoimmune disease characterised by the production of antinuclear antibodies directed particularly against native DNA. Its presence increases the susceptibility to develop other autoimmune diseases including autoimmune dysthyroidism. We present the case of a patient who presented with profound hypothyroidism as part of the work-up for lupus nephropathy. Female patient, 40 years old, reports physical asthenia for 2 months. On clinical e...

Introduction: -Thyroid disorders can predate or develop during pregnancy. -The effects on the fetus vary depending on the disease and the drugs used for treatment. But usually, untreated or undertreated hyperthyroidism can lead to harmful complications.Case report: It’s a 26-year-old patient with a history of goiter since childhood, history of goiter in the mother; grandmother and maternal aunt. the patient is 18 weeks pregnant, the pregnancy is unp...

We report a case of small cell neuroendocrine carcinoma of laryngeal localization. The involvement of the larynx still exceptional. We present in this paper the radiological, pathological and therapeutic aspects of this tumor that was diagnosed in a 48-year-old man. A 59 years old male patient, chronic smoker, with 10 packs per year; without any particular medical history. he consulted for a rapidly progressive cervical swelling since one year, associated with dysphonia. The w...

Introduction: Pheochromocytoma is a rare tumor of chromaffin cells localized in the adrenal gland. It is responsible of secretion of catecholamines in a supra physiologic amount, leading to hypertension. Some patients may present with hypotension despite having high circulating levels of catecholamines. The challenge is to stabilize blood pressure by medication in cases with fluctuation of blood pressure.Case presentation: 49-year-old woman suffered from...