Searchable abstracts of presentations at key conferences in endocrinology

ea0081p213 | Thyroid | ECE2022

Tuberculosis and myxedema coma − clinical case

Saraiva Miguel , Maia Ariana , Assuncao Guilherme , Amaral Claudia , Freitas Claudia , Couto de Carvalho Andre

Introduction: Myxedema coma is the ultimate stage of severe long-standing hypothyroidism, representing a true endocrinological emergency. Many precipitating factors have been identified, including the initiation of certain drugs.Case report: An 89-year-old woman was admitted to our emergency department due to an inaugural seizure. There was a history of progressive functional deterioration in the last 7 weeks, short after being diagnosed with lymph node ...

ea0049ep496 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Maturity onset diabetes of the young - clinical characteristics of a portuguese cohort

Amado Ana , Almeida Raquel , Carvalho Andre , Amaral Claudia , Freitas Claudia , Bacelar Conceicao , Vilaverde Joana , Cardoso Maria Helena , Teixeira Sofia , Borges Fatima

Introduction: Maturity onset diabetes of the young (MODY) accounts for 1-2% of all forms of diabetes mellitus (DM). As classic criteria that lead to its suspicion have low sensitivity, patients are often misdiagnosed with type 1 or type 2 DM. Correct classification of this type of diabetes becomes essential for proper management of the disease. Our objective was to describe clinical features of patients with MODY diagnosed at our institution.Methods: We ...

ea0035p769 | Obesity | ECE2014

Relationship of serum TSH with BMI, weight and HOMA-IR in euthyroid obese subjects

Garrido Susana , Caldas Ana Rita , Pereira Teresa , Carvalho Andre , Amaral Claudia , Freitas Claudia , Carvalho Rui , Bravo Fatima , Oliveira Jose Carlos , Cardoso Helena

Introduction: Most obese subjects have a normal thyroid function. Despite that, serum TSH seems to be slightly higher in this population, with a positive correlation with the degree of obesity.Objective: Evaluation of the relationship of serum TSH with BMI, weight, and HOMA-IR in euthyroid obese subjectsMethods: Three hundred obese subjects attending an Obesity Outpatient Clinic and submitted to bariatric surgery between January 20...

ea0032p733 | Obesity | ECE2013

Gastric banding vs gastric bypass: evolution of anthropometric parameters and related comorbidities during the 2 years after surgery

Caldas Ana Rita , Silva Ana Maia , Amaral Claudia , Freitas Claudia , Carvalho Andre Couto , Silva Isabel , Pichel Fernando , Silva Carla , Marcos Mario , Santos Jorge , Nogueira Carlos , Cardoso Maria Helena

Introduction: Bariatric surgery has proved to be effective in the management of morbid obesity. Our purpose was to compare the results obtained with adjustable gastric banding (GB) and Roux-en-Y Gastric Bypass (RYGB) during 2 years of follow-up after surgery, with regard to anthropometric parameters and related comorbidities.Methods: We evaluated prospectively patients who underwent GB and RYGB between 2004 and 2010 and compared the evolution of anthropo...

ea0081rc3.1 | Rapid Communications 3: Thyroid 1 | ECE2022

Usefulness of the EU-TIRADS score on sparing thyroid nodules cytology: a retrospective study

Puga Francisca , Silva Vânia Benido , Carvalho Andre , Freitas Claudia

Introduction: Incidental diagnosis of thyroid nodules has increased in recent years, leading to thyroid cancer diagnosis inflation. Nonetheless, mortality rate for thyroid malignancies remains very low, suggesting that its treatment is unlikely to affect the overall prognosis in the majority of cases. Several thyroid imaging scores have been proposed to reduce unnecessary invasive diagnostic procedures. Our aim was to verify the usefulness of the EU-TIRADS score on sparing thy...

ea0049ep1279 | Thyroid (non-cancer) | ECE2017

Metastatic differentiated thyroid carcinoma: cumulative doses of adjunct 131i-iodide therapy

Gouveia Patricia , Pereira Teresa , Amado Ana , Teixeira Ricardo , Costa Antonio , Carvalho Andre , Freitas Claudia , Borges Fatima

Introduction: 131I-iodide therapy (RIT) is an important treatment modality for patients with differentiated thyroid carcinoma (DTC). However, despite the overall excellent outcome, some DTC patients with poor prognosis may require multiple doses of radioactive iodine.Aim: The purpose of our study was to evaluate the efficacy of cumulative doses (CDs) of RIT in metastatic DTC patients.Material and methods: A retrospective study was ...

ea0037ep865 | Thyroid cancer | ECE2015

Incidental papillary thyroid carcinoma prevalence in benign multinodular goitre: data from Northern Portugal

Pereira Maria Teresa , de Carvalho Andre Couto , Freitas Claudia , Borges Fatima

Introduction: Incidental papillary thyroid carcinoma (PTC) in patients undergoing thyroidectomy for benign multinodular disease is a well-recognised finding. Its true prevalence remains uncertain and shows great variability between studies, ranging from 7–25%. Our purpose was to review the prevalence of PTC in thyroid glands removed for benign nodular disease at a Northern Portuguese tertiary hospital.Methods: From December 2012 to December 2014, th...

ea0035p329 | Clinical case reports Thyroid/Others | ECE2014

Two serious complications of propylthiouracil treatment in the same patient: case report

Garrido Susana , Pereira Teresa , Marinho Antonio , Freitas Claudia , Vilaverde Joana , Amaral Claudia , Carvalho Andre , Borges Fatima

Introduction: Thionamides are important drugs in the treatment of hyperthyroidism. Despite that, they can be associated with rare but serious complications, which require drug discontinuation.Case report: Sixty-five-year-old woman with Graves’ disease, treated in 2002 with methimazole and in remission until 2012. Recurrence of Graves’ disease was diagnosed in March 2012 and she was started on propylthiouracil (PTU) 150 mg per day. She presented...

ea0035p457 | Diabetes complications | ECE2014

Diabetic ketoacidosis and olanzapine: case report

Garrido Susana , Pereira Teresa , Freitas Claudia , Vilaverde Joana , Amaral Claudia , Carvalho Andre , Borges Fatima

Introduction: Patients with psychotic or depressive disorders have an increased risk of developing metabolic syndrome, not only because of their unhealthy lifestyle (sedentary habits, inadequate diet and smoking) but also because of the negative impact of antipsychotic agents (specially clozapine and olanzapine) on several metabolic features. These include overweight/obesity, dyslipidemia, development of new-onset type 2 diabetes, worsening of pre-existing diabetes and diabeti...

ea0056p1112 | Thyroid (non-cancer) | ECE2018

Levothyroxine absorption test: a safe help for difficult cases

Lopes Ana , Teresa Pereira Maria , Lito Pedro , Freitas Claudia , Teixeira Sofia , Cardoso Helena

Levothyroxine (L-T4) is the mainstay of treatment of hypothyroidism. Marked elevation of thyrotropin (TSH) in patients on high replacement doses is rare and can result from malabsorption, drug interaction or poor compliance. The levothyroxine absorption test is required to distinguish these causes and has proved to be safe. This test measures the serum free thyroxine (FT4) response to 1 mg of oral L-T4 over 4–24 h.Clinical cases: Case no 1: A 28-yea...