Endocrine Abstracts

Traditionally, male hypogonadism is classified into hypogonadotrophic (the archetype being Kallmann syndrome) and hypergonadotrophic (the archetype being Klinefelter syndrome). Late-onset hypogonadism (LOH) constitutes a separate entity that can be defined as the state where men of advanced age demonstrate low serum testosterone (T) concentrations in combination with a spectrum of symptoms reminiscent of those of ‘classic’ male hypogonadism (e.g. reduced sexual funct...

Background and aim: Low energy availability (LEA) may lead to menstrual disorders and low bone mineral density, predisposing to the female athlete triad (FAT) syndrome. The primary aim of this review was to systematically investigate the impact of sports on the energy status of professional female athletes compared to sedentary, recreationally active controls, with regard to their menstrual status and bone mineral density (BMD). A secondary aim was the estimation of the combin...

Objective: To systematically review and meta-analyze the best available evidence regarding the effect of vitamin D supplementation, either as monotherapy or in combination with protein and exercise, on sarcopenia indices (muscle strength, muscle mass, muscle performance).Materials and methods: A comprehensive search was conducted in Medline, Cochrane Central, and Scopus databases, up to December 31st, 2018. Data were expressed as standardized ...

Introduction: Gestational Diabetes Mellitus (GDM) is a disorder of glucose tolerance which is diagnosed for the first time during pregnancy. Thyroid disease is common in women of reproductive age and during gestation; both diseases have an adverse impact on pregnancy outcomes. The aim of this study was to assess the clinical and ultrasonographic characteristics in women with co-existing GDM and thyroid disease.Material and methods: In total, 112 pregnant...

Introduction: The aim of this study was to systematically review the literature for studies that have investigated possible differences in prevalence of subclinical Cushing’s syndrome (SCS) and related clinical implications between patients with unilateral (UAI) and bilateral adrenal incidentalomas (BAI) and to meta-analyze the best evidence available.Methods: Electronic databases PubMed, MEDLINE and EMBASE were systematically searched. Main study o...

Introduction: The role of thyroxine (T4) during embryo development is recognised as crucial. The research question of this study was if embryo quality and reproductive outcomes after IVF are affected by maternal thyroid function and/or thyroid auto-immunity (TAI).Methods/design: We conducted a prospective study (ThyrART), assessing embryo quality and reproductive outcome of women undergoing ovarian stimulation with a flexible GnRH-antagonist p...

Introduction: The evidence of the impact of OS for IVF and thyroid function or autoimmunity is inconclusive, based mainly on assessments just before and after OS. The aim of this study was to closely monitor the changes on thyroid function and autoimmunity throughout OS for IVF.Description of methods/designs: In a prospective, interventional study, a flexible GnRH-antagonist protocol was applied to 42 women undergoing IVF ((classic or ICSI), with initiat...

Introduction: Fear of illness and quality of life have been proven to be affected in women with osteoporosis. Osteoporosis causes an increase in morbidity and mortality but the direct ways by which it affects fear of illness and quality of life are not yet known. The present study aims to assess the fear of illness and quality of life (QoL) as well as their correlation with bone density and age in a Greek rural population of postmenopausal women with osteoporosis.<p class=...

Aim: To investigate reproductive function disorders in young women with type 1 diabetes mellitus (T1DM).Patients and methods: We studied 53 women with T1DM (duration 8.0±5.6 y) and 51 healthy controls with normal menstrual cycles and no clinical hyperandrogenism, matched for age (19.4±4.3 vs 20.8±3.1 years, P=0.063) and body mass index (BMI) (22.2±2.7 vs 21.4±1.9 kg/m2, P=0.088). T1DM (insulin regimen...

Objectives: To estimate the body mass index (BMI) distribution among Greek female adolescents in 2012 and to compare it with data from 2000, to find associations of obesity with dietary and social factors, as well as to determine the prevalence of acne, hirsutism and menstrual irregularities in the same population.Methods: All female students (n=380) aged 12–18 years of two randomly selected high schools, after obtaining a written consent f...