ea0070ep563 | Hot topics (including COVID-19) | ECE2020
Hadj Ali Zohra
, Htira Yosra
, Ben Mami Feika
Introduction: Pseudoxanthoma elasticum (PXE), a multisystem heritable disorder, is characterized by ectopic mineralization of soft connective tissues. It is an autosomal recessive disorder in which mutations in the ABCC6 gene result in low levels of inorganic pyrophosphate (PPi).In its classic form, PXE is a late-onset, slowly progressing disease, and the major clinical problems relate to development of vascular complications, including hypertension, int...