Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp81 | Diabetes (1) | ECE2016

Predictive variables of GLP-1 levels in postpartum reassessment of women with previous history of gestational diabetes

Maraver-Selfa Silvia , Jose Picon-Cesar Maria , Munoz-Garach Araceli , Mancha-Doblas Isabel , Tinahones Francisco

Objective: To study the GLP-1 pattern of secretion after an oral glucose tolerance test (OGTT) in women in postpartum reassessment of previous gestational diabetes (GDM). To evaluate clinical and laboratory parameters that can influence GLP-1 secretion.Patients and methods: Forty-eight women with a history of GDM were assessed one year after childbirth determining clinical and analytical characteristics and OGTT with 75 g. We measured glucose, insulin an...

ea0041ep481 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

Influence of obesity and carbohydrate metabolism disorders in GLP-1 levels in women with history of gestational diabetes mellitus

Maraver-Selfa Silvia , Jose Picon-Cesar Maria , Molina-Vega Maria , Mancha-Doblas Isabel , Tinahones-Madueno Francisco

Introduction: There is a reduction of the incretin effect in patients with type 2 diabetes secondary to altered secretion of incretin hormones and/or failed of its action.Objective: To study the GLP-1 secretion pattern after an oral glucose tolerance test (OGTT) in postpartum reassessment of women with previous GDM.Materials and methods: Prospective epidemiological study of 48 women with a history of GDM. We evaluated age, history ...

ea0090ep1112 | Late Breaking | ECE2023

Metabolic Control and Perinatal Outcomes According to The Planning or Lack of Planning of The Pregnancy

Fernandez Valero Andrea , Jose Simon Frapolli Victor , Generoso Pinar Marta , Molina Vega Maria , J Tinahones Francisco , Jose Picon Cesar Maria

Objectives: To analyze the data of patients seen at the Diabetes and Pregnancy Unit, assessing the frequency of pregnancy planning and whether there are differences in the degree of metabolic control before and during pregnancy, as well as in perinatal outcomes with respect to those who do not plan. All women of childbearing age with Pregestational Diabetes Mellitus(PGDM) should receive preconception counseling to optimize glycemic control, since preconception control is assoc...

ea0081p240 | Thyroid | ECE2022

Development of a laboratory alerting system for the early diagnosis of thyroid dysfunction in pregnancy

Ignacio Martinez Montoro Jose , Jose Simon Frapolli Victor , Fernandez Valero Andrea , Molina Vega Maria , Cobos Andres , Tinahones Francisco J. , Jose Picon Cesar Maria

Introduction: Overt thyroid dysfunction in pregnancy without an early diagnosis and treatment may lead to an increased risk of adverse maternal and fetal outcomes. In this study, our goal was to assess the results of the development of a laboratory alerting system for the diagnosis of thyroid dysfunction in the first trimester of pregnancy. Material and methods: Observational retrospective study evaluating clinical and biochemical data from pregnant wome...

ea0081ep252 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Comparative analysis of characteristics of pregnant women with pathological oral glucose tolerance test vs negative oral glucose tolerance test in a trimester of 2019

Simon Frapolli Victor Jose , Ignacio Martinez Montoro Jose , Picon Cesar Maria Jose , Gutierrez Repiso Carolina , Suarez Arana Maria , Tinahones Madueno Francisco Jose , Molina Vega Maria

Introduction: Gestational diabetes mellitus (GDM) is the metabolic disorder most frequently associated with pregnancy, presenting important maternal and fetal implications. Strict glycemic control through lifestyle measures and/or pharmacotherapy is essential to achieve adequate obstetric-perinatal results. The objective of this study is to compare baseline characteristics and perinatal results in patients diagnosed with GDM after performing oral glucose tolerance test (OGTT) ...

ea0063p622 | Diabetes, Obesity and Metabolism 2 | ECE2019

Assessment of materno-fetal complications in pregnant women with type 1 diabetes exposed to insulin degludec

Martinez Montoro Jose Ignacio , Hernandez Garcia Carmen , Jose Picon Cesar Maria , Molina Vega Maria , Maria Diaz Perdigones Cristina , Damas Fuentes Miguel , Jose Tinahones Madueno Francisco

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

ea0056p361 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Phenotypic and autoimmunity analysis of patients with type 1 diabetes mellitus onset

Maria Diaz Perdigones Cristina , Hern Carmen , Damas Fuentes Miguel , Jose Picon Cesar Maria , Luis Pinzon Martin Jose , Molina Vega Maria , Tinahones Madueno Francisco

Introduction: Type 1 diabetes mellitus (T1DM) is considered, in general, a disease of children and young adults with normal body mass index (BMI), linked to a genetic susceptibility based on autoimmunity. However, we know that it can be diagnosed at any age and we must differentiate it from type 2 diabetes mellitus.Objetives: To investigate the phenotypic characteristics and the presence of specific autoimmunity in T1DM patients diagnosed in our hospital...

ea0090ep1096 | Late Breaking | ECE2023

Subtypes of gestational diabetes based on indices of insulin sensitivity and insulin secretion

Fernandez Valero Andrea , Maria Linares Pineda Teresa , Lima Rubio Fuensanta , Molina Vega Maria , Gutierrez Repiso Carolina , Pena Montero Nerea , Suarez Arana Maria , Maria Fernandez Ramos Ana , J Tinahones Francisco , Jose Picon Cesar Maria , Morcilo Sonsoles

Objectives: Some authors have defined subtypes within gestational diabetes (GD) based on the calculation, from glucose and insulin levels during oral glucose overload (OGTT), of indices of insulin sensitivity (Matsuda) and insulin secretion (Stumvoll). Powe et al [1] found that 30% of women with GD had predominantly low insulin secretion, 51% low insulin sensitivity and 18% both (mixed). The aim of this work is to analyze the correlation of these indices with other kn...