Searchable abstracts of presentations at key conferences in endocrinology

ea0056p353 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Decreased spexin levels in patients with type 1 diabetes

Karaca Anara , Bakar Filiz , Ersoz Gulcelik Nese

Spexin is a novel peptide which has a potential role as a biomarker of insulin resistance, diabetes and obesity. We aimed to investigate spexin levels in lean type 1 diabetes patients and spexin’s role on glycemic parameters without the presence of obesity or insulin resistance.Patients and methods: This cross-sectional study included 29 type 1 diabetic patients and a control group of 23 healthy subjects adjusted for age, sex and body mass index (BM...

ea0049ep317 | Clinical case reports - Thyroid/Others | ECE2017

The parathyroid carcinoma in a young adult male

Nur Firat Sevde , Karaca Anara , Colak Bozkurt Nujen , Unverdi Hatice

Introduction: Parathyroid carcinoma is a rare malignancy of the parathyroid glands. Parathyroid carcinoma may be suspected, but it usually cannot be confirmed prior to operation.Case: A 35-year-old male was consulted to Endocrinology department with persistant kidney stones. He was operated five times in 10 years for recurrent kidney stones.His lab results are as follows; Ca:13(8.8–10.6), P:2.2 mg/dl(2.5–4.5), ALP:84U/L(3...

ea0049ep854 | Clinical case reports - Pituitary/Adrenal | ECE2017

A case of cystic prolactinoma responsed to medical treatment

Omma Tulay , Gulcelik Nese Ersoz , Karaca Anara , Taskaldiran Isilay

Introduction: Cystic prolactinomas are considered resistant to volume depletion by dopamine agonists (DAs). Because of the effectiveness and tolerability, dopamine agonists (DAs) are the first line therapies in prolactinoma and reduce tumor mass as well as prolactin levels in most of all patients. Rathke’s cleft cysts, craniopharyngiomas and arachnoid cysts are differential diagnoses to keep in mind. DAs resistance or intolerance, psychiatric disorders associated with dop...

ea0090ep398 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Watch out! Starvation ketoacidosis mimicking diabetic ketoacidosis

Karaca Anara , Sreejith Gopika , Mahamud Bashir , Maningas III Casimiro Cruz , Roy Juthi , Mlawa Gideon

Background: Starvation ketoacidosis (SKA) represents one of three metabolic acidosis caused by the accumulation of ketone bodies in blood. While easily treated, it is a diagnosis that can be easily mimic diabetic ketoacidosis, particularly in the presence of hyperglycemia1.Case: We report a 54-year old female, who had been feeling unwell with ongoing nausea and vomiting, and not eating nor drinking for 5 days. She had a history of alcohol exce...

ea0090ep879 | Pituitary and Neuroendocrinology | ECE2023

Pituitary Tumours and Learning Difficulties-An Association or Incidental Finding?

Bashir Mahamud , Etbinah Lubna , Oyesanya Ayodeji , Ramachandran Kirtanya , Mohammed Mohammed , Karaca Anara , Mlawa Gideon

Introduction: Pituitary tumours one of the most commonly occurring intracranial neoplasms accounting for up to the 15 % of all intracranial neoplasms. Pituitary tumours are often associated with overproduction of hormones or, when they are large, they cause mass effect on surrounding neural structures which are adjacent to their typical location in the Sella turcica. Due to their multifaceted effects pituitary tumours may cause cognitive impairment due hormonal deficiency or m...

ea0049ep344 | Endocrine tumours and neoplasia | ECE2017

Differential roles of carboxylated and uncarboxylated Osteocalcin in stage I breast cancer as a diagnostic biomarker

Karaca Anara , Gulcelik Nese Ersoz , Bakar Filiz , Akgul Giray , Sahiner Zeynep , Gulcelik Mehmet Ali

Objective: The finding of new biomarkers is needed to have an early diagnosis of breast cancer. In this study we evaluated serum levels of carboxylated osteocalcin (OC) and uncarboxylated osteocalcin(UcOC), CRP as a diagnostic biomarker for breast cancer.Design and methods: Blood samples of 39 women with newly diagnosed breast cancer with stage I were obtained before surgery and 39 age and BMI matched health women were selected as controls.<p class="...

ea0049ep384 | Clinical case reports - Pituitary/Adrenal | ECE2017

Prediction of type 1 diabetes in autoimmune polyglandular syndrome type 2

Karaca Anara , Gulcelik Nese Ersoz , Omma Tulay , Taskaldiran Isilay , Firat Sevde Nur , Bozkurt Nujen

Introduction: Autoimmune Polyglandular Syndrome (APS) is a very rare endocrinopaty, characterized by the coexistence of at least two glandular autoimmune mediated diseases. In this case a patient presented with hyperpigmentation of the whole body, significant weight loss for last 6 months.Case: A-49 year old male were refered to our deparment with loss of appetite, fatigue, nausea, weight loss and with marked buccal pigmentation. Blood pressure was 80/50...

ea0049ep1175 | Male Reproduction | ECE2017

A case with taurodontism and Klinefelter syndrome

Taskaldiran Isilay , Omma Tulay , Karaca Anara , Taskaldiran Alper , Ersoz Gulcelik Nese

: In this paper we present an 18-year-old patient with Klinefelter syndrome who has taurodontism. Klinefelter syndrome is the most common abnormality of sex chromosomes. It is characterized by hypogonadism, gynaecomastia, azoospermia or oligospermia, and increased levels of gonadotropins. Associated medical disorders can be categorized as follows; cancer, autoimmune disorders, intellectuel and psychiatric disorder, osteoporosis, endocrine disorders, venous disease and taurodon...

ea0056ep92 | Interdisciplinary endocrinology | ECE2018

FGF21 levels in patients with breast cancer

Sahiner Zeynep , Karaca Anara , Bakar Filiz , Akgul Giray , Ali Gulcelik Mehmet , Gulcelik Nese Ersoz

Aim: FGF-21, is a member of the FGF family that is involved in biological processes such as embryonic development, cellular growth, morphogenesis, tissue repair, tumor growth and invasion, with mitogenic and cellular vital activity activity in the cytogenetic localization of 19q13.33. Breast cancer is the fatal disease most commonly seen in women and increasing in frequency and the relationship between hormones secreted from adipose tissue and some cancers has been shown in re...

ea0037ep972 | Thyroid (non-cancer) | ECE2015

Pentraxin 3 levels in patients with Hashimoto disease

Aydin Unsal , Culha Cavit , Aktas Aynur , Keskin Muge , Ozcan Muge , Karaca Anara , Omma Tulay , Gulcelik Nese Ersoz , Koc Gonul , Aral Yalcin

Pentraxin 3 (PTX3) is produced from several cell types in case of inflammation. PTX3 has been investigated in several autoimmune diseases. As Hashimoto disease is an autoimmune disease of thyroid, we investigated the role of PTX3 levels in patients with Hashimoto disease.Objective: The aim of this study was to investigate the relationship between PTX3 and autoimmune thyroiditis.Methods: The study subjects were classified as four gr...