Endocrine Abstracts

Introduction: The term female pattern hair loss (FPHL) is commonly used synonymously with female androgenetic alopecia. While the the role of androgens and androgen receptor genes is well-defined in male androgenetic alopecia (AGA-M), its role in in the pathogenesis of FPHL is stil uncertain. More diffuse involvement, resulting in an oval-shaped alopecia surrounded by a rim of normal hair density (Luduig’s classification) might be a clinical challenge. The aim of case rep...

Introduction: Some physiological changes in HbA1c during pregnancy should be considered to determine its optimal value for glycemic control. Erythrocytes half-life decreases during pregnancy, which is reflected in a decrease in HbA1c.Aim: The aim of this study is to analyse HbA1c during pregnancy in healthy population of pregnant woman. Matherial and methods: The study included 77 pregnant women in the first trimester registered in Center for endocrinolo...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions with an increase in insulin resistance, moderate, reversible increase in lipid concentration in the blood, and accumulation of fat stores in the mother’s tissues. Lipid metabolism is essential for the development of healthy pregnancy, and fatty acids are a significant source of energy and a key element for membrane synthesis, while cholesterol, in addition ...

Introduction: Acquired modifible long QT syndrome (LQTS) might be caused by hypocortisolism but also drug-induced. Unique genetic association between them is the background of both. The aim of this case report is to present the patient with Addison disease and LQTS not responding on increased dosage of hydrocortison susbstitution therapy.Case report: We report a female patient, 65 years old (1950y.). At the age of 34y. (1984y.) Morbus Addisoni was diagno...

Introduction: Rapid progression of atherosclerosis is classicaly described after e.g. percutaneous transluminal coronary angioplasty or it is defined as an diameter reduction of a preexisting stenosis. However, both initiation and perpetuation mechanisms are rarely descibed in patients on supraphysiological dosages of glucocorticoids (GCs).Case report: We present male patient, 53-year old, after transsphenoidal operation of hypophysis pp. craniopharyngeo...

Introduction: Growth without growth hormone is seen also in patient with craniopharyngioma. We just speculate what anabolic factors might be involved in this process. However, oestrogen through its receptors lead to epiphyseal fusion. In this case report we would like to present the patient with bilateral slipped femoral epiphysis (SFE) and interventions made at tertiary health care level.Case report: 20-years-old female, operated from craniopharyngioma ...

Background: In the 2019 ESC Guidelines on diabetes, pre-diabetes and cardiovascular diseases, only retinopathy appears as a target organ damage as a parameter for stratification patients into very high-risk group. The aim of study was to check the strength of association between DN and isolated DR groups with cardiovascular complications.Methods: Chronic kidney disease (CKD) was defined by eGFR ≤ 59 ml/min/1.73 m2 and proteinuria (P...

Introduction: The fact that up to 33% with type 2 diabetes develop hypogonadotropic hypogonadisms (HH), are still not catching enough attention. More futher ’’the 5-year mortality of somebody who has got diabetes, who has had a myocardial infarction is actually lower than the diabetic patient who has developed a diabetic foot ulcer, which is around 48%’’.Case description: We describe male patient, 47 y. (on 2016y), newly diagnosed...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions. During early gestation, the fetus is dependent on maternal thyroid hormones that cross the placenta. Thyroid disease in pregnancy is a common clinical problem, at least 2–3% of women have thyroid dysfunction. Pre-conceptual education and appropriate diagnosis and treatment of thyroid dysfunction in early pregnancy are of great importance, with the aim of ...

Introduction and objectives: The aim of our study was to determine which characteristics of the uncontrolled diabetes are among randomly selected patients with type 1 (T1DM) and type 2 (T2DM) diabetes.Material and methods: A total of 194 diabetic patients were observed, 142 with T2DM and 52 with T1DM, recruted in outpatient clinic. Patients were divided into three groups according to HbA1c values: <7% (G1), 7–8% (G2) and >8% (G3). Statistica...