Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep69 | Adrenal and Cardiovascular Endocrinology | ECE2022

Epidemiological and clinical data and factors of poor blood pressure control in known hypertensive patients in the Sfax region

Mkaouar Fatma , Mnif Fatma , Boujelben Khouloud , Jdidi Jihen , Abid Mohamed

Introduction: Hypertension is a very common chronic disease worldwide. Its imbalance is one of the main causes of cardiovascular and neurodegenerative complications.Patients and Methods: We collected data from hypertensive patients who voluntarily presented for screening on both diabetes and hypertension screening days.Poor blood pressure control was defined as systolic blood pressure (SBP) greater than or equal to 140 mmHg and/or diastolic blood pressur...

ea0056p1086 | Thyroid (non-cancer) | ECE2018

Segregation of S292F TPO gene mutation in three large Tunisian families with thyroid dyshormonogenesis: evidenceof a founder effect

Ghorbel Dorra , Hadjkacem Faten , Mnif Fatma , Loukil Fatma , Mnif Mouna , Elleuch Noura , Abid Mohamed

We aimed to identify causal mutation(s) in 13 patients with thyroid dyshormonogenesis (TD) from three consanguineous Tunisian families. A 12-year clinical follow-up showed phenotypic variability ranging from the presence to the absence of goiter, sensorineural deafness, and mental retardation. Genetic analysis using microsatellite markers within two candidate genes (TPO and PDS) gave evidence of linkage with the TPO gene. Sequencing of its 17 exons and their flanking intron-ex...

ea0063p1097 | Pituitary and Neuroendocrinology 3 | ECE2019

Predictive factor of hypopituitarism in prolactinoma

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Charfi Nedia , Rekik Nabila , Abid Mohamed

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

ea0037ep85 | Adrenal cortex | ECE2015

Subclinical Cushing's syndrome: report of 17 cases

Kacem Faten Haj , Cheikhrouhou Nesrine , Charfi Nadia , Lassoued Najwa , Mnif Fatma , Mnif Mouna , Rkik Nabila , Abid Mohamed

Introduction: Subclinical Cushing’s syndrome refers to autonomous cortisol secretion in patients who do not have the typical signs and symptoms of hypercortisolism. This study was undertaken to describe clinical, biological and radiological features of this disease and to evaluate the clinical outcome after surgical and medical treatment.Methods: Retrospective study conducted over a period of 12 years and including 17 patients hospitalised in our de...

ea0037ep534 | Diabetes (complications & therapy) | ECE2015

Diabetic foot infection: study of 109 patients

Kacem Faten Hadj , Ammar Mouna , Charfi Nadia , Cheikrouhou Nesrine , Mnif Fatma , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Diabetic foot infection (DFI) is a major public health problem, both for its morbid clinical consequences mainly ulcers and the economic social cost due to repeated hospitalisations and the high rate of amputation.Objectives: Analyse the clinical presentation of DFI, study risk factors of developing this infection and describe the therapeutic management.Materials and methods: Retrospective study spread over 8 years ol...

ea0073ep75 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Systemic diseases and diabtes

Chabchoub Imen , Elleuch Mouna , Kacem Faten Hadj , Ben Salah Dhoha , Charfi Nadia , Mejdoub Nabila , Mnif Fatma , Mnif Mouna , Mohamed Abid

IntroductionThe association of type 1 diabetes with other autoimmune diseases is well known due to a common genetic terrain of varied clinical expressions. However, the occurrence of systemic diseases in diabetic patient, whatever the type of diabetes, is poorly studied. The objective of this study is to describe autoimmune and inflammatory diseases associated with diabetes.Materials and methodsIt ’ s a ...

ea0073ep163 | Pituitary and Neuroendocrinology | ECE2021

Analysis of clinical and biological features of non-functioning pituitary adenomas: A retrospective study

Kacem Faten Hadj , Boujelben Khouloud , Imene Ghariani , Salma Gdoura , Nadia Charfi , Mouna Mnif , Fatma Mnif , Nabila Rekik , Mohamed Abid

IntroductionNon-functioning pituitary adenomas (NFPA) present approximately 15% to 30% of all pituitary adenomas. They are most commonly misdiagnosed, until they are large enough to lead to mass effect and hypopituitrasm. The present study was carried out with the aim of studying the clinical and biological characteristics of patients who are followed for NFA.Patients and methodsThis is a retrospective study ...

ea0081ep392 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Diabetic foot: a tunisian experience

Elleuch Mouna , Frikha Hamdi , Ben Salah Dhoha , Mnif Fatma , Mnif Mouna , Charfi Nadia , Rekik Majdoub Nabila , Haj Kacem Akid Faten , Abid Mohamed

Introduction and aim: Diabetic foot (DF) is associated with increased morbimortality and cost of diabetes management. The aim of this study is to describe the epidemiological, clinical and paraclinical characteristics and follow-up outcomes of patients with diabetic foot in a Tunisian center.Methods: It is a monocentric retrospective study of 210 patients with diabetic foot followed at the endocrinology department of the Hedi Chaker Sfax University Hospi...

ea0081ep726 | Pituitary and Neuroendocrinology | ECE2022

Predictive factors of biological remission in patients with prolactinoma treated with dopamine agonists

Elleuch Mouna , Frikha Hamdi , Fatma Loukil , Salah Dhoha Ben , Souissi Matiem , Mnif Fatma , Mnif Mouna , Charfi Nadia , Majdoub Nabila Rekik , Akid Faten Haj Kacem , Abid Mohamed

Introduction and aim: Dopamine agonists (DA) are prescribed as first-line treatment for prolactinomas and are generally effective and well tolerated. However, the degree and quickness of therapeutic response is variable among patients. The aim of this work is to study the predictive factors of biological remission in patients with prolactinoma treated with DA. Methods: A single-center, retrospective and analytical study of patients with prolactinoma foll...

ea0063p1053 | Pituitary and Neuroendocrinology 3 | ECE2019

Prolactinoma and elderly subject: which caracteristics?

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Safi Wajdi , Zargni Asma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Rekik Nabila , Charfi Nedia , Abid Mohamed

Introduction: Prolactinoma is the most common secretory pituitary adenomas. It has clinical and biological characteristics that depend on age, gender and tumor size. Prolactinoma of the old subject is a rare clinical form that was not sufficiently treated in the literature.Materiels and methods: It is a retrospective study including 77 cases of prolactinoma among which 3 cases aged over than 65 years. The collection of data was made between 2000 and 2017...