Searchable abstracts of presentations at key conferences in endocrinology

ea0081p537 | Adrenal and Cardiovascular Endocrinology | ECE2022

Management of persistent subclinical hypercortisolism post left adrenalectomy in a patient with primary bilateral macronodular adrenal hyperplasia with aberrant receptors

Moustaki Melpomeni , Papadimitriou Kasiani , Papanikolaou Vasiliki , Cherolidi Eleni , Rigana Maria , Kyriakopoulos Georgios , Kalogeris Nikolaos , Vryonidou Andromahi

Introduction: Endogenous subclinical hypercortisolism occurs in 5-30% of patients with adrenal incidentalomas. Adrenal adenoma is the commonest cause of autonomous cortisol secretion (ACS), while primary bilateral macronodular adrenal hyperplasia (PBMAH) is rare. In both, ACS results from activation of the cAMP/PKA pathway. This may be triggered by ligands, other than ACTH, acting upon aberrant G-protein coupled receptors (GPCRs), which may also control locally produced ACTH i...

ea0081p248 | Late-Breaking | ECE2022

The differences between normocalcemic and hypercalcemic primary hyperparathyroidism: a tertiary center′s experience

Kalogeris Nikolaos , Papanikola Nektaria , Herolidi Eleni , Palioura Eleni , Papanikolaou Vasiliki , Loi Vasiliki , Vryonidou Andromahi

Introduction: Normocalcemic Primary Hyperparathyroidism is today considered a variant of Primary Hyperparathyroidism. It is characterized by persistently normal calcium levels and increased levels of parathyroid hormone, after the exclusion of other causes of secondary hyperparathyroidism. We aimed to compare clinical, biochemical and imaging data from patients with normocalcemic and hypercalcemic primary hyperparathyroidism. Methods: This is a retrospec...

ea0090p373 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Glycemic control in Type 1 Diabetes patients using multiple daily insulin injections (MDII) vs continuous subcutaneous insulin infusion (CSII)

Tsitsimpis Anastasios , Cherolidi Helen , Kalogeris Nikolaos , Spanou Loukia , Mouslech Tzant , Somali Maria , Georgiopoulos Georgios , Vryonidou Andromachi

Objective: Glycemic control of patients with type 1 diabetes is mainly based on insulin administration. The ongoing technological developments in continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII) provide new treatment strategies, with better glycemic control. This study assessed the clinical impact of two treatment strategies in adults with type 1 diabetes (T1D): multiple daily insulin injections (MDII) vs continuous subcutaneous insulin i...

ea0041ep785 | Obesity | ECE2016

Interventional changes of thyroid hormone levels do not affect circulating irisin levels in humans

Panagiotou Grigorios , Pazaitou-Panayiotou Kalliopi , Komninou Despina , Paschou Stavroula A. , Kalogeris Nikolaos , Vryonidou Andromachi , Mantzoros Christos S.

Introduction: Thyroid hormones and irisin increase energy expenditure and induce browning of adipose tissue. However, little is known about irisin physiology and regulation. Here we aim to elucidate whether thyroid hormones alter circulating irisin concentrations in humans.Design and subjects: One cross-sectional (case-control) evaluation and two interventions were performed independently from each other, including previously thyroidectomized patients. C...

ea0070aep226 | Bone and Calcium | ECE2020

The incidence of nephrolithiasis and osteoporosis in patients with asymptomatic hyperparathyroidism

Polymeris Antonis , Kalogeris Nikolaos , Lafkas Apostolos , Papanikola Nektaria , Herolidi Eleni , Kogia Christina , Vryonidou Andromahi

Introduction: The clinical profile of patients with primary hyperparathyroidism has changed significantly in the last decades considering the fact that most cases are asymptomatic. This could be attributed to early diagnosis due to routinely serum calcium measurement. Only 5–27% of patients present with symptoms or signs related to osteoporosis, nephrolithiasis and hypercalcaemia. However, in patients with asymptomatic primary hyperparathyroidism (APHP) data concerning t...

ea0056p431 | Diabetes complications | ECE2018

Atherosclerosis in women of reproductive age with type 2 diabetes mellitus and polycystic ovary syndrome

Paschou Stavroula A , Kalogeris Nikolaos , Proikaki Stella , Loi Vasiliki , Anagnostis Panagiotis , Vryonidou Andromachi

Introduction: The aim of this study was to investigate the degree of atherosclerosis in women of reproductive age with type 2 diabetes mellitus (T2DM), with and without polycystic ovary syndrome (PCOS).Patients and Methods: 71 women (mean age 43.2 y) with T2DM treated with diet or oral anti-diabetic medications and 36 controls were studied. According to menstrual cycle and clinical hyperandrogenism, patients with T2DM were classified into two subgroups, ...

ea0056p950 | Female Reproduction | ECE2018

Oxidative stress markers in women with polycystic ovary syndrome without insulin resistance

Gyftaki Reveka , Gougoura Sofia , Kalogeris Nikolaos , Loi Vasiliki , Koukoulis George , Vryonidou Andromachi

Introduction: Polycystic ovary syndrome (PCOS) is usually accompanied by abdominal obesity and insulin resistance which are related with low-grade chronic inflammation, as evidenced by elevation of multiple markers of inflammation, among which is oxidative stress. However, as far as oxidative stress presence, the existing data are limited. The purpose of this study was the investigation of several oxidative stress markers in women with PCOS without insulin resistance.<p cl...

ea0049ep239 | Bone &amp; Osteoporosis | ECE2017

Endocrine disorders in treatment-naïve male patients with HIV infection

Kalogeris Nikolaos , Nezi Markella , Chini Maria , Lioni Athina , Sakka Vissaria , Mangafas Nikolaos , Kaoustou Styliani , Lazanas Marios , Vryonidou Andromachi

Objective: To investigate endocrine disorders concerning bone metabolism, thyroid and gonadal axis in treatment–naïve HIV-infected male patients.Subjects and methods: We studied 70 male, treatment-naïve patients (stage A=60, stage B=10) from the Infectious Diseases Unit of our Hospital. Anthropometric indices were measured and BMI was calculated for each participant. Blood samples were obtained after an overnight fasting for the evaluation...

ea0041gp219 | Thyroid Cancer | ECE2016

Prognostic factors for tumor invasiveness in papillary thyroid microcarcinomas

Polymeris Antonios , Mizamtsidi Maria , Travlos Alexis , Katsoulis Georgios , Dimitropoulou Fotini , Dermentzoglou Alexandros , Kalogeris Nikolaos , Tzioras Constantinos , Vryonidou Andromachi

Introduction: Papillary thyroid microcarcinomas (PTMC) are usually considered low-risk tumors with favorable prognosis. However, a small percentage behaves aggressively and controversies exist for various prognostic factors. The aim of this study was to evaluate demographic and tumor specific characteristics related to PTMC invasiveness.Patients – methods: This is a retrospective study of 510 thyroidectomized patients with PTMC who were treated in t...

ea0073aep823 | Late Breaking | ECE2021

A case of euglycaemic ketoacidosis and concomitant acute pancreatitis in a diabetic patient treated with SGLT2i and GLP-1RA

Moustaki Melpomeni , Kalogeris Nikolaos , Katsafyloudi Maria , Papanikola Nektaria , Rigana Maria , Spanou Loukia , Angelopoulos Theodoros , Kalantzis Ioannis , Vryonidou Andromahi

IntroductionGlucagon-like peptide 1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) are the two novel classes of anti-diabetic agents with compelling efficacy, in terms of glucose-lowering and cardio-renal protection. Euglycemic diabetic ketoacidosis (EDKA) is a serious rare adverse effect of SLT2i while the use of GLP-1RA has been scarcely linked with acute pancreatitis in humans.Case presentatio...