Endocrine Abstracts

Introduction: Thyroid incidentaloma detected by FDG-PET/CT (flourodeoxyglucose positron emition tomography/computed tomography) is important because of high rate of malignancy. Elastosonograpghy has proven valuable in discriminating malign and benign thyroid lesions. In this study, we aimed to evaluate PET incidentalomas by ultrasonography and elastosonography and to compare cytopathological results with imaging findings.Methods: A total of 50 patients i...

Background: A rare cause of ectopic Cushing’s Syndrome (ECS) is pulmonary neuroendocrine neoplasm (NEN) with a broad spectrum of clinical behavior. At the time of diagnosis, pulmonary NENs may present as occult tumors or well-defined round-to-oval lesions in close relationship to the bronchus. Herein, we describe a NEN that developed ECS three years later in a patient followed up for a solitary pulmonary nodule (SPN).Case Presentation: A 56-year-old...

Introduction: Papillary thyroid carcinoma (PTC) is the most common endocrine cancer however extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) of the thyroid gland is quite rare. The simultaneous association of both cancers is much more rare.Case report: 65-year-old woman underwent a thyroid ultrasound examination due to palpable thyroid nodules. Thyroid ultrasound revealed thyroiditis and multiple nodules on the right and ...

Introduction: Thyrotropinomas are usually considered when the TSH level is inappropriately elevated or normal in a hyperthyroid patient with increased serum T4 levels, regardless of the presence of visible tumor on imaging. The prevalence of these adenomas, which account for 0.5–3% of all pituitary tumors has been estimated to be around one case per million. Most thyrotroph adenomas are large and invasive at diagnosis, and present with signs and symptoms of an ...

Background and aim: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder in women with reproductive age. Nodular goiter and autoimmune thyroid disease (AITD) are frequently seen endocrinological abnormalities. The aim of this study was to identify the prevalence of AITD and nodular goiter in PCOS patients and investigate whether PCOS related hormones and metabolic factors affect these thyroid disorders.Methods: Ninety-seven with ...

Background: Hypoparathyroidism is an uncommon disorder of calcium metabolism characterized by hypocalcemia, hyperphosphatemia, and reduced level of parathyroid hormone (PTH). The most common cause of hypoparathyroidism is accidental damage to the parathyroid glands during thyroid surgery. There are no formal guidelines for hypoparathyroidism management. The main goal of treatment is to improve the symptoms of hypocalcemia, to keep the serum calcium within the low normal range,...

Objective: Cardiovascular diseases (CVD) are the most important cause of mortality in acromegaly patients. Noninvasive assessment of aortic stiffness which can be used as an predictor of atherosclerosis, may be of benefit in acromegaly patients for early diagnosis of CVD. We evaluated the aortic elasticity parameters of acromegalic patients in remission and compared with healthy controls.Methods and results: Study subjects consisted of 20 patients with a...

Objective: Acromegaly is associated with increased morbidity and mortality, mostly due to cardiovascular complications. The objective of the present study was to evaluate the echocardiographic epicardial fat thickness in acromegaly patients.Methods and results: We evaluated 25 consecutive patients with acromegaly (15 females, 10 males, mean age 44.5±10.1 years), and 22 age-matched control subjects (12 females, 10 males, mean age 37.40±7.5 years...

Diabetic ketoacidosis (DKA) seen in 10–70% of patients with type 1 diabetes mellitus (DM1) has a significant risk of mortality. We present a DKA in a patient with DM1 resulted in hypokalemia related ECG abnormalities that the diagnosis needed to be differentiated from acute coronary syndrome. A 18-year-old women without any significant past medical history admitted to hospital with a two day history of fatique, weakness, nausea, vomiting. Patient appeared hipovolemic. Vit...

Objective: The aim of this study was to determine the change in serum ischemia-modified albumin (IMA) level and oxidative stress markers (total antioxidant status, TAS, total oxidant status, TOS) in patients with metabolic syndrome (metS).Research design and methods: We studied 52 metS patients (56.74±12.75 mean age), and 36 control subjects (54.47±6.52 mean age). The presence of metS was diagnosed according to National Cholesterol Education Pr...