Endocrine Abstracts

Aim: To evaluate the serum levels of resistin and adiponectin, and the potential relationship between these adipokines, thyroid function, lipid profile, C-reactive protein (CRP) and homocysteine levels in patients with autoimmune thyroiditis (AIT) and subclinical hypothyroidism (SCH).Methods: patients with AIT (58 females; 47.7±16.7 years) were studied; 33 of them had also SCH. These patients were diagnosed by a positive result in an anti-peroxidase...

Aim: The aim of this study was to evaluate the association between thyroid function in Graves’ disease (GD) with high-sensitivity C-reactive protein (hs-CRP), lipid profile, homocysteine, folate, vitamin B12 and insulin resistance.Methods: We performed a cross-sectional of 104 patients with recently diagnosed GD. All participants were in the first cycle of treatment with methimazole. We collected demographic information, body mass indexes (BMI), lab...

Aim: To evaluate the relationship between autoimmune thyroiditis (AIT), subclinical hypothyroidism (SCH) and cardiovascular risk factors.Patients and methods: We recorded thyroid function tests, BMI, insulin resistance markers comprising the homeostasis model assessment for insulin resistance (HOMA-IR and HOMA-B), the quantitative insulin sensitivity check index (QUICKI), hepatic insulin sensitivity index (HISI), whole-body insulin sensitivity index (WBI...

Introduction: Graves’ disease is an autoimmune disease accounting for the majority of hyperthyroidism cases.Aim: We aimed to assess the interrelationships between cardiovascular risk factors, autoimmunity, insulin resistance and treatment in Graves’ disease.Material and methods: We measured free T3 (FT3), free T4 (FT4), TSH, thyrotropin receptor antibodies (TRAb), anti-thyroglobulin and anti-TPO antibodies, thyro...

Introduction: Thyroid dysfunction has been associated with cardiovascular events since it worsens atherogenesis, insulin resistance and dyslipidemia. Thyroid hormones and adipokines interact with each other to regulate metabolism. The impact of thyroid dysfunction on adipokines serum levels remains controversial.Objective: To evaluate the interrelations between thyroid function and cardiovascular risk factors as insulin resistance, lipid profile, inflamm...

Introduction: The interrelationship between autoimmune thyroiditis, Graves’ disease and plasma adipokines levels remains elusive.Aims: We aimed to compare the levels of adiponectin, resistin and PAI-1 levels in patients with autoimmune thyroiditis and Graves’ disease.Subjects and methods: We recorded thyroid function tests, BMI, the levels of total cholesterol (TC), HDL, LDL-cholesterol, triglycerides (TG), apolipoprotein...

Background: Overt thyroid dysfunction is associated with an increased cardiovascular risk. The impact of subclinical hypothyroidism and autoimmunity in the increased cardiovascular risk remains controversial. Aim: To evaluate the interrelations between thyroid function, thyroid autoimmunity and cardiovascular risk factors, in patients with autoimmune thyroiditis (AIT).Methods: 353 subjects with AIT were evaluated. We defined three groups based on TSH lev...

Background: Thyroid hormones modulate the lipoprotein and glucose metabolisms. In hyperthyroidism, insulin resistance is a frequent finding.Aim: To assess interrelationships between thyroid function, autoimmunity, lipid profile, glucose metabolism and other cardiovascular risk factors in patients with Graves’ disease.Methods: We recorded free T3 (FT3), free T4 (FT4), TSH, TSH receptor antibodies (TRAB), parameters of the lipid...

Introduction: In patients with autoimmune thyroiditis, thyroid function appears to be related to increased cardiovascular risk. It was our objective to evaluate the relationship between TSH, insulin resistance, lipid profile, C-reactive protein (CRP) and homocysteine in patients with autoimmune thyroiditis (AIT).Methods: We analyzed the lipid profile, the CRP, anti-thyroid antibodies, homocysteine, folic acid, vitamin B12 levels and the insulin resistanc...

Introduction: Subclinical hypothyroidism appears to be related with an increased risk of cardiovascular disease. It was our objective to evaluate the relationship between autoimmune thyroiditis, subclinical hypothyroidism, and cardiovascular risk factors.Methods: We evaluated thyroid function tests, autoimmunity, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, ApoA1, ApoB, Lp(a), homocysteine, high sensibility CPR, folic acid, vitamin...