Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep1166 | Late Breaking | ECE2022

Does Autonomic cortisol secretion really affect metabolic parameters? preliminary results

Karslı Seda , Turgut Seda , Acarer Bugun Didem , Pamuk Naim , Piskinpasa Hamide , Cakir İlkay , Mert Meral , Ciftci Sema

Aim: Autonomic cortisol secretion (ACS) is a clinical picture without overt signs of Cushing’s Syndrome despite adrenal adenoma and ACTH-independent cortisol secretion. These patients, who currently do not have a standard treatment, are followed up, especially for known comorbidities of hypercortisolemia such as obesity, diabetes mellitus (DM), hypertension, osteoporosis, and hyperlipidemia. However, it remains unclear how long the patients will be followed and when the t...

ea0041ep917 | Pituitary - Clinical | ECE2016

The role of p16 and MDM2 gene polymorphisms in tumorigenesis and characteristics of prolactinoma

Turgut Seda , Ilhan Muzaffer , Turan Saime , Karaman Ozcan , Yaylim Ilhan , Kucukhuseyin Ozlem , Tasan Ertugrul

Introduction: Prolactinomas are thought to arise from the proliferation of a mutated pituitary stem cell which is subjected to the growth stimuli of several permissive factors, although the pathogenetic mechanisms underlying the tumorigenesis still remain unclear. The present study aimed to investigate the role of p16 (540C→G and 580C→T) and MDM2 (SNP309T→G) gene polymorphisms in tumorigenesis and characteristics of prolactinoma.Methods...

ea0035oc1.1 | Thyroid clinical | ECE2014

Esophagus motility in overt hypothyroidism

Ilhan Mahmut Muzaffer , Arabaci Elif , Turgut Seda , Karaman Ozcan , Danalioglu Ahmet , Tasan Ertugrul

Introduction: Gastrointestinal tract is one of the most affected systems in hypothyroidism. The most plausible mechanism in the pathogenesis is the development of interstitial edema subsequent to accumulation of glycosaminoglycans. Despite decreased esophageal emptying, prolonged esophageal and gastric transit time has been indicated in previous reports, the mechanism of thyroid hormones activity on the gastrointestinal system is not yet fully understood. To our knowledge, thi...

ea0081ep1185 | Late Breaking | ECE2022

The role of preoperative thyroid function tests in weight loss after bariatric surgery in morbidly obese patients

Acarer Bugun Didem , Turgut Seda , Seyit Hakan , Pamuk Naim , Pişkinpaşa Hamide , Bozkur Evin , Karabulut Mehmet , Mert Meral

Background: Obesity is one of the most critical problems nowadays, its frequency and consequences. Since the risk of morbidity and mortality increases in obese individuals, lifestyle changes, pharmacotherapy, and bariatric surgery (BS) methods are used for treatment. BS is generally considered the most effective method to treat morbid obesity. However, it is known that thyroid function has a role in weight regulation, the effect of preoperative thyroid function on weight loss ...

ea0073aep505 | Pituitary and Neuroendocrinology | ECE2021

Increased anxiety and perceived stress in active acromegaly during the COVID-19 pandemic

Turgut Seda , Piskinpasa Hamide , Acarer Didem , Karaarslan Ozlem , Bozkur Evin , Pamuk Naim , Cakir Ilkay , Mert Meral , Dogansen Sema Ciftci

AimTo examine and compare the anxiety level and stress perception of acromegaly patients with controlled and active disease in the COVID-19 pandemic.Material and Method49 (23 females/26 males) patients admitted to the outpatient clinic during the first month after the pandemic period were recruited in this cross-sectional study. State-Trait Anxiety Inventory (S-Anxiety for state scale, T-Anxiety for trait sca...

ea0081p768 | Late-Breaking | ECE2022

Insulin-Like Growth Factor-I might be a predictor for severe nonalcoholic fatty liver disease in morbidly obese patients

Turgut Seda , Acarer Bugun Didem , Seyit Hakan , Pamuk Naim , Pişkinpaşa Hamide , Bozkur Evin , Karabulut Mehmet , Cakır İlkay

Aim: To compare the IGF-1, metabolic and clinical parameters among the ultrasonographically classified NAFLD groups, to examine the effect of weight loss on metabolic parameters and determine the factors that may predict the NAFLD severity in morbidly obese patients who underwent bariatric surgery.Method: This descriptive cross-sectional study was conducted in 316 morbidly obese patients (250 females, 66 males). The data of patients before and 1st year a...

ea0081ep1183 | Late Breaking | ECE2022

Weight loss induced by bariatric surgery may improve systemic inflammation: Preliminary results

Pamuk Naim , Turgut Seda , Seyit Hakan , Acarer Bugun Didem , Pişkinpaşa Hamide , Bozkur Evin , Karabulut Mehmet , Cakır İlkay

Background: Obesity is a widespread disease that causes chronic low-grade inflammation and related chronic diseases such as steatohepatitis, metabolic syndrome, diabetes mellitus (DM), and cancer. It is known that weight loss positively affects life expectancy by reducing obesity-related complications. Therefore, effective management of particularly morbidly obese patients is getting prominent in clinical practice. Bariatric surgery (BS) is the main effective treatment option ...

ea0070aep156 | Bone and Calcium | ECE2020

DXA scanning in primary hyperparathyroidism: Should forearm DXA be performed routinely?

Piskinpasa Hamide , Ciftci Dogansen Sema , Metin Duygu , Alper Sahbaz Nuri , Aydın Husnu , Esen Ayse , Bozkur Evin , Turgut Seda , Pamuk Naim , Cakir Ilkay , Mert Meral

Introduction: Primary hyperparathyroidism (PHPT) is a disease associated with a decrease in bone mineral density (BMD), especially in cortical bones such as distal radius. Therefore, the BMD measurement of forearm is valuable in the detection of cortical bone loss by PHPT. However, forearm measurement is not routinely recommended for the diagnosis of osteoporosis in PHPT. In this study, we aimed to evaluate the importance and priority of forearm BMD measurement in PHPT.<p ...

ea0073aep422 | General Endocrinology | ECE2021

The effect of COVİD-19 process on patients with endocrinological disease in a pandemic hospital: What Happened to the others?

Bozkur Evin , Turgut Seda , Pamuk Naim , Piskinpasa Hamide , Metin Duygu , Dural Cem , Sahbaz Nuri Alper , Omur Gunaldı , İlkay Cakir , Mert Meral , Dogansen Sema Ciftci

ObjectiveTo evaluate the effects of the pandemic process on those with an endocrinological disease that will require close follow-up from the last visit before the pandemic.DesignThis was a retrospective study.MethodsPatients of 3903 with thyroid, calcium-bone metabolism, adrenal gland, pituitary diseases, and neuroendocrine tumor (NET) were retrospectively scanne...

ea0073aep489 | Pituitary and Neuroendocrinology | ECE2021

Disease activity is associated with depression and anxiety in cushing’s syndrome during COVID-19 pandemic

Piskinpasa Hamide , Turgut Seda , Karaarslan Ozlem , Bozkur Evin , Ayşe Esen Pazır , Pamuk Naim , Ilkay Çakir , Mert Meral , Dogansen Sema Ciftci

PurposeTo assess the depression and anxiety and their relationship with disease activity in patients with Cushing’s syndrome (CS) in the COVID-19 pandemic.Material and methodsThis is a cross-sectional study including 54 patients with CS (48 female/6 male). Beck Depression Inventory-II (BDI-II), State Trait Anxiety Inventory (STAI)-State, STAI-Trait were used to evaluate, scores and severity of depression...