Endocrine Abstracts

Introduction-Aim: Manifest dream content is rarely studied in dream research. Conflicting results have been presented regarding dream recall and affect vis-à-vis the menstrual cycle. Progestagens may improve dream recall. Thus, we aimed to assess dream recall/affect vis-à-vis the menstrual cycle in a large sample of women.Subjects-methods: We studied 779 women (mean age +S.D.: 31+9 years). The subjects were give...

Aim: To evaluate the efficiency of glucocorticosteroids (GCS) in combination with biological therapy in the treatment of COVID-19 in patients with type 2 diabetes mellitus (T2D).Materials and methods: A retrospective study of hospitalized patients with a PCR-confirmed diagnosis of COVID-19 with T2D was conducted (n=179). Patients received standard therapy, including biological preparations. The first group consisted of participants who received ...

Introduction: The occurrence or worsening of thyroid eye disease (TED) after SARS-CoV-2 mRNA vaccines is extremely rare whereas has not been reported following viral vector vaccination. In the region of South-West Greece during the COVID-19 pandemic, a case of de novo appearance of TED referred to the Endocrinology Department of our hospital, following viral vector SARS-COV-2 vaccine.Case report: The patient was a 62-year-old woman, heavy smoker (40 pack...

Introduction: Morgagni–Stewart–Morel syndrome is defined as the absolute presence of hyperostosis frontalis interna, associated with metabolic, endocrine, and neuropsychiatric disorders. There are very few cases reported in the literature and some experts do not even recognize it but the exact etiology of the syndrome remains unclear; some theories relate to estrogen dysfunction, obesity and leptin dysfunction, and genetic alterations....

Introduction: Simultaneous pancreas-kidney transplantation (SPKT) is the best way to restore normoglycemia and renal function in patients with type 1 diabetes mellitus (T1D) and end-stage renal disease (ESRD). Pregnant patients after SPKT are a high-risk group for adverse events/loss fetal and transplantation organs. These risks are significantly reduced due to pregnancy planning, regular monitoring of the woman and fetus condition with timely correction of immunosuppressive t...

Introduction: The aim of this study was to evaluate predictors of metabolic disease in normal weight postmenopausal women.Patients and Methods: This cross-sectional study included 457 non-obese postmenopausal women, recruited from the Menopause Clinic of Aretaieio Hospital, National and Kapodistrian University of Athens. The diagnostic criteria of the International Diabetes Federation for the definition of Metabolic Syndrome were used, in order to classi...

Introduction: The hypothalamic-pituitary-ovarian and/or adrenal axis as well as the autonomous nervous system affect significantly the intensity of menopausal symptoms Pre-existing levels of stress may affect the individual perception of menopausal symptoms. We aimed to evaluate the efficacy of a structured stress management program to reduce levels of stress and severity of climacteric symptoms, in a sample of middle-aged Greek women.Methods: The sample...

Introduction: Recent studies have shown that microRNA could serve as biomarkers in various types of cancer and other diseases. Aim: To reveal microRNA that differ in patients with Cushing’s diseases (CD) and Ectopic ACTH-syndrome (EAS) to form a specific panel for differential diagnosis of ACTH-dependent Cushing’s syndrome (CS).Materials and Methods: Plasma samples from both sinuses and cubital vein were drained during in...

Androgen therapy is the mainstay of treatment in female to male (FtM) transgender persons to increase testosterone levels, suppress oestrogens and treat gender dysphoria. Testosterone is widely used for male hypogonadism, but is comparatively under-investigated in FtM transgender persons. The aim of our study was to identify treatment and safety outcomes associated with testosterone use in transgender medicine. A literature search was conducted in PubMed/Medline, as well as EM...

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease ranging from simple intrahepatic lipid accumulation to fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). 5β-reductase (AKR1D1) is a liver enzyme that catalyses a fundamental step in bile acid (BA) synthesis. Both BAs and BA intermediates are established as potent regulators of metabolic and proliferative phenotype. We have hypothesised that AKR1D1 plays a crucial role in NAFLD and HCC. Human liver b...