Endocrine Abstracts

Aim: Atypia/follicular lesion of undetermined significance(AUS/FLUS) is a category of thyroid cytology with features that are neither definitely benign or malignant. We aimed to determine whether specific cytologic or architectural features are associated with malignancy in AUS/FLUS category of Bethesda system according to subgroups.Methods: The specimens of patients who underwent surgery with preoperative thyroid fine neeedle aspiration (FNA) biopsies o...

Introduction: Although malignancy rate is low in thyroid nodules with nondiagnostic (ND) cytology, it is reported as higher in persistent ND nodules. We aimed to determine the role of ultrasonography (US) features and Thyroid Imaging Reporting and Data System (TIRADS) in the prediction of malignancy in patients with persistent ND cytology.Methods: 246 patients who underwent thyroidectomy with an indication of at least two ND cytologies were included in t...

Introduction: Recently, it has been suggested that thyrotropin (TSH) concentration can be used as a marker for prediction of thyroid malignancy. However, the association between the cytology results and TSH levels is not clear. In this study, we aimed to investigate the relationship between TSH levels and Bethesda categories and determine the role of TSH levels in prediction of malignancy in patients with different Bethesda categories.Methods: The data o...

Introduction: Incidental thyroid carcinoma (ITC) in patients operated on for a benign disease is frequent. ITC characteristics in patients operated for malign disease, but not sampled by fine needle aspiration (FNA) or seen in ultrasonography, is unknown. We aimed to compare ITC with nonincidental ITC (NITC) in this study.Material and method: Retrospective analyses of 918 individual patients who were operated for benign and malign thyroid disease in our ...

Background: We aimed to evaluate malignancy rate in thyroid nodules ≥4 cm and determine false negativity of fine needle aspiration biopsy (FNAB) in these nodules.Methods: Patients who underwent thyroidectomy between January 2007 and December 2014 in our institution were reviewed. Demographical and clinical data and preoperative ultrasonography (US) findings were obtained from the medical records. The nodules in these patients were grouped as &#8805...

Background: Fine needle aspiration biopsy (FNAB) has proven to be the most valuable diagnostic procedure for preoperative discrimination of benign and malignant nodules. Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has standardized reporting and cytomorphological criteria in aspiration smears. In this study, we aimed to determine malignancy rates in nodules with different cytology results and diagnostic value of TBSRTC for variants of papillary thyroid carcinom...

Introduction: In this study, we aimed to evaluate impact of multifocality, tumor number and total tumor diameter on clinicopathological features of PTC.Methods: Medical records of 912 patients who underwent thyroidectomy and diagnosed with PTC were reviewed retrospectively. Patients were grouped into 4 according to number of tumoral foci; N1 (1 focus), N2 (2 foci), N3 (3 foci) and N4 (≥ 4 foci). The diameter of the largest tumor was considered as t...

Introduction: The increased rate of thyroid malignancy as well as incidental and subcentimeter thyroid nodules have been attributed to increasing use of high-resolution US which can detect the non-palpabl or subcentimeter (maximum diameter ≤1 cm) thyroid nodules. We aimed to evaluate the sonographic features of the tyroid nodules between ≤1 cm and > 1 cm according the histopathology results and to determine the ultrasonographical predictive factors for malignan...

Introduction: In this study, we aimed to evaluate the usefulness of ratio of primary tumor diameter to total tumor diameter as a new parameter for the differentiation of agressive and favorable papillary thyroid microcarcinomas (PTMC).Methods: The diameter of the largest tumor focus was taken as the primary tumour diameter (PTD). For multifocal tumors, total tumor diameter (TTD) was calculated as the sum of the maximal diameter of each lesion. A ratio wa...

Introduction: Primary hyperparathyroidism (PHP) is a highly prevalent disease, which is treated most effectively by surgery. Postoperative hypocalcaemia, a morbidity of surgical treatment of parathyroidism, can prolong the hospital stay. The aim of this study was to identify the factors predictive of hypocalcaemia and hungry bone syndrome (HBS) in patients who undergo parathyroidectomy due to PHP.Materials and methods: Preoperatively and on days 1 and 4,...