Endocrine Abstracts

Introduction: Disorders of glucose metabolism are often present in chronic liver diseases. The aim of our study is to determine the prevalence and factors associated with type 2 diabetes in patients with cirrhosis.Methods: This is a retrospective study collecting all patients with cirrhosis between January 2010 and December 2019.Results: During the study period, 166 patients were included. Of these patients, 47 patients had type 2 ...

Dyslipidemia is a frequent pathology, especially in diabetics, which may require the use of lipid-lowering drugs such as statins. Our goal is to determine the impact of these molecules on the metabolic profile of a diabetic population with dyslipidemia.Methods: This is a retrospective study including 150 patients followed at the Tunis nutrition institute for diabetes and dyslipidemia.Results: The average BMI was 31.4 ± 6.1 kg/...

Introduction: Diabetic neuropathy is a degenerative complication of diabetes mellitus which can be restrictive. The objective of our work is to determine the prevalence of this complication in a type 2 diabetic population as well as its different risk factorsMethods: This is a retrospective study including 100 Tunisian type 2 diabetic patients followed up in the ‘C’ department at the National Nutrition Institute in Tunis.<p class="abstext...

Forty-seven years old lady presented to another hospital with symptoms of diarrhea and sleep disturbance. She was found to have abnormal thyroid function tests (TFTs) with fT4 44 fT3 12 and TSH 3.4. She had no goiter or thyroid eye signs. Thyroid ultrasound showed a multinodular goiter and an uptake scan was consistent with thyrotoxicosis.She was commenced on carbimazole and in 2001 radio-iodine was administered for a presumed diagn...

Somatostatin is a hormone and neuropeptide expressed in the pancreas, gastrointestinal tract, hypothalamus, and other tissues. It regulates directly the secretion of insulin, glucagon, many of the gastrointestinal hormones, and growth hormone. It is therefore surprising the somatostatin knockout (sst-ko) mice have a very mild phenotype. We subjected sst-ko mice and heterozygous siblings which served as controls to a high-calorie diet, and confirmed that sst-ko mice gain weight...

Introduction: Diabetes increases the risk of high blood pressure, atherosclerosis, coronary heart disease and stroke. Therefore, People with diabetes have an increased cardiovascular risk. Arterial stiffness is a marker of cardiovascular risk and has been shown to have an independent prognostic effect on cardiovascular disease. The aim of this study was to examine the relationship between cardiovascular risk and arterial stiffness in type 2 diabetes.Meth...

Introduction: Type 2 diabetes is an insidious and progressive disease; accounting for about 90% of all diabetes cases worldwide. Atherosclerosis is a common pathology in diabetes that involves a combination of fatty degeneration (atherosis) and stiffening of the arterial vessels (sclerosis), and the best tool to evaluate the arterial stiffness is the pulse wave velocity. The aim of this study is to evaluate the arterial stiffness in type 2 diabetic patients.<p class="abste...

Introduction: Microangiopathy is defined as damage to small blood vessels, and more particularly arterioles and arteriolar capillaries that supply organs. It can occur under different conditions and it represents a complication of diabetes. The aim of this study was to examine the relationship between microangiopathic complications and arterial stiffness in type 2 diabetes.Methods: We conducted a prospective study including 249 diabetic patients without ...

Introduction: Elderly diabetics are often fragile patients at high cardiovascular risk. The medical, human and socio-economic impact of diabetes is heavy in the elderly. Symptoms in this particular population are often insidious and atypical, which can delay diagnosis and the establishment of effective treatment. Indeed, management is not always easy because it must take into account multiple parameters. The objective of our study was to study the observance and particularitie...

Introduction: Diabetes mellitus is a disease that is progressing at an alarming rate in the world. In the elderly, the symptoms are often insidious and atypical, which can delay the diagnosis and the establishment of effective treatment. Indeed, management is not always easy because it must take into account multiple parameters. The objective of our study was to study the clinico-biological and etiological profile of diabetes discovered after the age of 65 years.<p class="...