Endocrine Abstracts

Introduction : Type 1 diabetes (T1DM) is an autoimmune disease that commonly affects a young population. Its evolution can be characterized by a frequent occurrence of degenerative complications. Our aims were to study microangiopathic complications, lipid profile, and the presence of other autoimmune diseases in type 1 diabetic patients whose diabetes has been evolving for 10 years or more.Method : This is a descriptive cross-sectional study including T...

Aim: The aim of our study was to compare the clinical profile of type 1 and type 2 diabetic patients who are hospitalized in our service for diabetic ketoacidosis.Methodology: This was a descriptive study involving 121 diabetic patients hospitalized for diabetic ketoacidosis in the C department of diabetology of the national institute of nutrition of Tunis.Results: Of the 121 subjects studied, 57.85% are type 2 diabetic patients an...

Introduction: Calcium intake is important to prevent osteoporosis in postmenopausal women. The objectives of our study were to evaluate the daily dietary calcium intake in postmenopausal Tunisian women, to compare diabetic and non-diabetic postmenopausal women in their calcium intake and finally to propose corrective interventions to promote calcium intake and minimize the complications of menopause.Subjects and methods: The study involved 73 postmenopau...

Introduction: TSH-secreting pituitary adenomas are rare pituitary functioning tumors accounting for <2% of the pituitary adenomas. Their association to meningiomas is a very rare condition.We report a case of 55-year-old woman who had multinodular goiter with mild symptoms of hyperthyroidism. Blood tests showed inappropriate secretion of TSH and magnetic resonance imaging (MRI) revealed a pituitary tumor with maximum diameter of 13 mm that was extirp...

Introduction: Dopamine agonist resistance is rare in prolactinoma (10%). Doses of cabergoline of up to 2.0 mg/week are usually effective in controlling prolactin (PRL) secretion and reducing tumor size. Surgical treatment is rarely indicated.Case report: An 18-year-old female presented in 2002 with a 2-year history of amenorrhea and galactorrhea. Hormonal investigation showed a hyperprolactinemia (4800 mUI/l) with integrity of the other pituitary axis. T...

Introduction: Weight loss is a mainstay in the treatment of polycystic ovary syndrome (PCOS). While the cause of this complex endocrine disorder remains unknown, it’s approved that weight loss improves symptoms of PCOS. We report a case of a patient with PCOS. Her symptoms disappeared totally after losing 50kgCase report: In 2005, a 16-year-old girl presented for evaluation of spaniomenorrhoea and obesity. Physical examination showed a weight of 88 ...

Introduction: Renal complications in Graves’ disease are rare and may be related either to the disease itself or secondary to antithyroid drugs.Methods: We report seven cases of renal damage in patients with Graves’ disease treated with Benzylthiouracyl collected over a period of 14 years.Results: There were seven women with a mean age of 37.86±14.25 years (19–61 years).Six patients develo...

Introduction: Systemic amyloidosis leads to functional compromise of various organs through infiltration of these tissues by amyloid protein.The aim of this study was to determine the endocrine disorders in patients with systemic amyloidosis.Methods: During the period from 1975 to 2006, we collected 580 patients with renal amyloidosis confirmed by histological exam. We selected 123 patients with hormonal exploration. 55 patients ha...

Introduction: Phaeochromocytoma and Cushing syndrome are two uncommon endocrine conditions. The association of these two conditions is very rare and not well elucidated. We report an association of a phaeochromocytoma with an ACTH-dependant Cushing syndrome.Case report: A 32-years-old female patient was admitted in the endocrine department for paroxysmal hypertension diagnosed in the immediate post partum period. She reported sweating and palpitation cri...

Introduction: Hyperprolactinemia is a common endocrine condition causing galactorrhoea. Breast abscess is a frequent complication of the post partum period and breast feeding but it rarely occurs out of these two situations. We report the case of a patient presenting with tumoural hyperprolactinaemia associated with a breast abscess.Case report: A 34 years-old patient presented with galactorrhoea, spaniomenorrhoea and headache for six months. She had not...