Endocrine Abstracts

Aim of the study: The aim of the study was to compare skin microvascular reactivity (MVR) with oxidative stress and metabolic parameters at fasting status and postprandially in patients with recently diagnosed type 2 diabetes.Methods: Twenty patients with type 2 diabetes (mean age 58±6 years, HbA1C 4.8±0.5%, diabetes duration 2.3±1.3 years, metformin treatment only) were included in the study. Blood samples were taken before and after 60, ...

Introduction: Cytological diagnostics has got an established position in thyroid diseases. In the recent years, attempts have been undertaken to use the biological material, left in needles after cytological preparation is ready, to obtain additional diagnostic data.Goal of study: The goal of the study was evaluation of the possibility to use the results of fine-needle aspiration biopsy (FNAB) for confirmation of either the presence or the absence of lym...

Background: Newborn screening is the only systematic work-up of thyroid disorders in Slovakia with unambigously proven positivities. There is wide discussion regarding the screening of thyreopathies in specific risk groups such as pregnant women.Aims: To study the gynaecologist and endocrinologist co-operation in screening pregnant patients from region of Liptov and Orava for autoimmune thyroiditis.Subjects and methods: The partici...

Transarterial chemoembolization (TACE) is widely used for treatment of hepatocellular carcinoma (HCC). During this procedure approximately 20 g of iodide is applied by radiopaque material. There is usually high awareness regarding hyperthyroidism in association with contrast enhanced imaging studies and TACE. To date, however, there are no reports regarding the frequency of hypothyroidism after this procedure, although high doses of iodide can also inhibit the synthesis of thy...

IntroductionPapillary thyroid cancer (PTC) has generally good prognosis irrespective of lymph node metastases. The rate of survival in patients with distant metastases is variable, depending upon the site of metastases and radioiodine accumulation status. The median survival of patients with brain metastases is approximately one year.CaseWe present a 66 years old woman with a tumour triplicity (PTC, breast ca...

Objective: Preoperative iodine therapy due to toxic nodular goiter (TNG) is discouraged as iodine may cause an aggravation of hyperthyroidism. In Graves’ disease iodine has been used for a century but little data is available on iodine treatment in TNG. We aimed to examine if a short course of iodine treatment is safe to administer in TNG.Method: 20 patients with TNG with persistent subclinical to mild hyperthyroidism were included at our tertiary c...

Introduction: Cushing’s syndrome (CS) is a rare disease with incidence estimated 2-4 cases per million inhabitants per year. ACTH-dependent forms comprise up to 80% of all cases, of which 80% are central and 20% are ectopic, paraneoplastic forms of ACTH-dependent CS. Thymic neuroendocrine tumors (NET) are accounting for 0,4 - 3% of all NET’s with incidence of 0.02/100 000 inhabitants/year. Up to one third of them are hormonally active (secrete adrenocorticotropic hor...

Introduction: Urinary iodine concentration (UIC) can reflex recent changes in iodine status and serve as a sensitive marker of current iodine intake. The cut-off value of UIC was determined as the level lower than 100 μg/l. Adequate median urinary iodine for iodine intake in pregnancy is 150–249 μg/l. The aim of this study was to map the situation of iodine intake in pregnant women with pregestational and gestational diabetes and to explore relationship with thy...

Introduction: Previous UK study (2009) showed that parents rather than school staff were responsible for supporting the majority of children with insulin administration (IA) whilst at school. Since then, the law has changed and the Children and Families Act 2014 (UK) places a legal duty on schools to provide the right care and support.Objective: To establish what support & facilities are available to Children & Young people (CYP) with TID whilst ...

Graves’ orbitopathy (GO) is a serious, progressive eye condition seen in patients with autoimmune thyroid disease. GO is characterized by inflammation and swelling of soft orbital tissues. Adipose tissue produces cytokine mediators called adipokines. The present study focuses on the relationship between serum levels of selected adipokines in patients with GO, comparing them with the control group, and uniquely describes the effect of high-dose systemic corticosteroids (HD...