Endocrine Abstracts

Introduction: Hashimoto’s thyroiditis (HT) is caused by a variety of genes, cytokines, receptors, and environmental factors. A series of enzymes known as type 1 and type 2 deiodinases (D1, D2) are in charge of converting thyroxine (T4) into triiodothyronine (T3). It is believed that the low free T3 (fT3) levels caused by D2 polymorphism may result in thyroid autoimmunity through the induction of inflammation. However, iodothyronine deiodinase (DIO) gene polymorphism and H...

Aim: The aim of this study was to determine the malignant potential of thyroid nodules with macrocalcifications and to evaluate the role of other sonographic findings in the diagnosis of malignancy in thyroid nodules besides macrocalcifications.Method: The findings of 8250 patients who applied to our outpatient clinic and underwent thyroid ultrasonography(US) between 2008 and 2021 were retrospectively reviewed. We included a total of 303 patients with 30...

Purpose: The coronavirus disease 2019 (COVID-19) has a high morbidity and mortality in patients with chronic disorders. This study was aimed at assessing the frequency and outcomes of COVID-19 in patients with lipodystrophy syndrome and investigating the effect of restricted access to the hospital during pandemic on metabolic parameters.Methods: A survey comprising descriptive questions about the situation of the patients during the COVID-19 pandemic was...

Lymphocytic infundibuloneurohypophysitis (LINH) is rarely reported due to lymphocyte infiltration in the neurohypophysis. Causes of central diabetes insipidus include idiopathic diabetes insipidus (DI), primary or secondary tumors or infiltrative diseases (such as Langerhans cell histiocytosis, lymphocytic hypophysitis), neurosurgery and trauma.Case: A 59-year-old female patient presented with complaints of fatigue for 1 month, dry mouth and drinking a l...

Aim: Diabetes and prediabetes become prevalent day by day, likewise their complications are also as important as they are. Lipid profile is also evaluated for cardiovascular diseases which are the major complications of diabetes and prediabetes. Non-HDL cholesterol has begun to be taken as one of the treatment goals, especially in diabetics, with respect to the recent dyslipidemia guidelines. The aim of this study is to compare non-HDL values in women with normal or impaired g...

Introduction and Aim: Thyroid dysfunction is the most common autoimmune endocrine disorder in women of reproductive age. Autoimmune thyroid disease is related to menstrual irregularities, anovulation and infertility. Thyroid dysfunction is thought to disrupt follicular growth and maturation. Autoimmunity may have a negative effect on fertility, independent of age. The relation between TSH (Thyroid Stimulant Hormone), thyroid antibodies and AMH (anti-mullerian hormone) is a top...

Aim: The risk of cardiovascular mortality is high in patients with acromegaly. In this study, we intent to evaluate serum lipid profile in patients newly diagnosed with acromegaly and determine its association with increased growth hormone (gh) and insulin like growth factor-1 (igf-1) levels.Material and method: This study includes 57 patients newly diagnosed with acromegaly in our hospital (mean age 44.1±13.8 years; mean bmi 29.6±5.4 kg/m...

Purpose: Papillary and follicular cancers are classified as differentiated thyroid cancers. Recently, it has been revealed that Neutrophile/lymphocyte ratio (NLO) and the ratio of monocyte/lipoprotein cholesterol with high density (MHR) are the strong indicators of oxidative stress and systemic inflammation. In this study, we intend the evaluation of all these indicators in our patients diagnosed with differentiated thyroid cancers.Method: This study inc...

Hypoparathyroidism is a rare endocrine disorder whose epidemiologic characteristics regarding the cause, clinical course, acute and chronic complications have not been well defined. There is also a substantial geographic variability regarding those parameters, and country-specific local data is scarce.This study was conducted to assess the baseline characteristics, including the demographics, etiologic distribution, disease severity, medications use...

Introduction: Parathyroid adenoma is the most frequent cause of primary hyperparathyroidism (PHPT). In recent years minimally invasive surgical techniques have challenged the traditional bilateral neck exploration. There are different imaging techniques for preoperative location of parathyroid adenomas. In this study the authors review the role of Doppler ultrasound focusing on its safety, availability and affordability.Aim: To evaluate the role of Doppl...