Endocrine Abstracts

Introduction: It has been reported that blind women with disturbed melatonin secretion have a lower incidence of breast cancer. A higher incidence of breast cancer has been reported in women in shift work, in which lower nocturnal melatonin secretion is observed. The anticancer action of melatonin is currently the focus of research interest.Aim: The aim was to study the effect of melatonin on MCF-7 breast cancer cells in vitro.<p class="abst...

Introduction: Melatonin is an indole being produced by the pineal gland and secreted mainly during the night. Melatonin is involved in the regulation of biological rhythms. The hormone possesses antioxidant action and is thought to be involved in the protection of the organism from the development of malignant tumors. Melatonin has been found to have anticancer action in vitro as is has been observed to inhibit the proliferation of cancer cells in vitro.<...

Introduction: Patients with autoimmune diseases are known to develop other autoimmune conditions. Adrenal insufficiency of autoimmune etiology is known to coexist with autoimmune diabetes mellitus, Hashimoto’s thyroiditis and vitiligo. However, Graves’ disease in the context of adrenal insufficiency of autoimmune etiology is rare.Aim: The aim was to describe the case of a patient who presented with fatigue and was diagnosed to have hyperthyroid...

Introduction: The SARS-CoV-2 virus has severely affected humanity. The disease causes pneumonia which may be severe. In many cases, patients, especially if there are comorbidities, may have a fatal outcome. The disease affects all organs and the variability of its manifestations has attracted intense scientific interest. Aim: The aim of the study was to describe the case of a patient who developed subacute thyroiditis after infection with the SARS-CoV-2 ...

Introduction: Leukopenia is a manifestation of autoimmune diseases such as systemic lupus erythematosus (SLE). Leukopenia may be an early sign of autoimmunity and may be a comorbidity in patients with autoimmune Hashimoto’s thyroiditis. Aim: The aim was to present a cohort of 12 patients with autoimmune Hashimoto’s thyroiditis who presented with leukopenia.Methods: A cohort of 12 patients, aged 19-72 y, female, with autoi...

Introduction: Patients with systemic sclerosis may develop cancer. The development of malignant hematological diseases has also been described in patients with systemic sclerosis. These patients may also be prone to the development of lymphoma, in most cases a B-cell lymphoma.Aim: The aim was to describe the case of a patient with systemic sclerosis who had a non-Hodgkin’s lymphoma and developed primary hypothyroidism.Case rep...

Vitamin D deficiency is increasingly recognized today having taken the form of a modern epidemic. Vitamin D, being synthesized in the skin under the effect of ultraviolet light has been originally thought of as occurring only in areas of the world where people are not exposed to the sun. However, it has recently been observed that vitamin D deficiency exists even in sunny areas. Recent observations suggest that vitamin D deficiency is related to significant comorbidity, specif...

Male osteoporosis is a reality and in many cases appears to be secondary to drug administration. Many pharmaceutical agents are related to the appearance of osteoporosis, affecting bone metabolism by multiple and diverse mechanisms.The aim was to describe the case of a patient who presented with male osteoporosis of multiple drug aetiology.A patient, male aged 52 years, an orthodox priest, presented with spontaneous fractures and d...

Introduction: Research results from different countries show that vitamin D deficiency is a modern reality, affecting even sunny countries. Vitamin D deficiency has been related to predisposition to the development of diabetes mellitus type 2 and it may affect the secretion and action of insulin.Aim: The aim was to study the effect of vitamin D on glycaemic control in patients with diabetes mellitus type 2.Materials and methods: Th...

Well differentiated thyroid carcinoma is associated with prolonged survival in terms of decades and anaplastic carcinoma is associated with survival in months. Intermediate malignancy with a more guarded prognosis is also known to exist.The aim was to describe the case of a patient with a mixed papillary, poorly differentiated and anaplastic thyroid carcinoma.A female patient, aged 73 years presented with a multinodular goiter and ...