Endocrine Abstracts

Systemic lupus erythematosus (SLE) is a multisystem multifactorial autoimmune disorder. The survival of SLE patients has been improved by the administration of immunomodulatory therapy. Patients, however, are affected by late onset complications of the disease such as atherosclerosis. Lipoprotein Lp(a) is a known risk factor for the development of atherosclerosis.The aim was to study Lp(a) levels and their relationship with disease activity in SLE patien...

Epidemiological studies indicate that rheumatoid arthritis (RA) patients have increased mortality. Cardiovascular disease seems to be one of the major causes of death in patients with RA. Lipoprotein disorders are observed in patients with systemic autoimmune disorders as well as in patients with RA. Lipoprotein Lp(a) is an independent risk factor for the development of cardiovascular disease.The aim of the study was estimate lipoprotein Lp(a) levels and...

Fine needle aspiration is used extensively in the diagnostic evaluation of thyroid nodules. However, its diagnostic efficacy may be reduced by non-diagnostic findings. The aim was to study the effect of nodule size on the diagnostic efficacy of ultrasound-guided fine needle aspiration biopsy in thyroid nodules.Ultrasound-guided fine needle aspiration biopsy was performed in 210 patients with thyroid nodules. Cytology results were compared to nodule size....

Ultrasound-guided fine needle aspiration biopsy is used extensively in the diagnostic evaluation of thyroid nodules. However, its diagnostic efficacy is hampered by the presence of non-diagnostic cytology results.The aim was to study the effect of previous thyroxine suppression therapy on the diagnostic efficacy of fine needle aspiration biopsy in thyroid nodules.Ultrasound-guided aspiration biopsy was performed in 45 patients, 31 ...

Adrenal carcinoma is a rare neoplasm with poor prognosis. Mitotane (o,p′-DDD) is the only known therapeutic agent with action on the adrenal. Although it has been used for many decades, its pharmacological properties and exact mechanism of action are still debated. It has been suggested that its therapeutic effect is dose-dependent (Baudin et al 2001). High performance liquid chromatography (HPLC) has been used for the exact measurement of mitotane dose.<p cla...

The detection of antithyroid antibodies, specifically of antithyroglobulin antibodies, in patients with differentiated thyroid carcinoma after near-total thyroidectomy, radioiodine therapy and thyroxine suppression presents difficulties in screening patients for residual disease or recurrence of the disease as it may interfere with thyroglobulin measurement. The aim of the study was to estimate the rate of decrease in antithyroid antibody levels in patients with differentiated...

Introduction: Bariatric surgery is a revolutionary method for the treatment of morbid obesity. It is effective as far as weight control is concerned, for the prevention and treatment of diabetes mellitus and the metabolic syndrome. However, bariatric surgery may be accompanied by adverse effects if postoperatively dietary instructions are not adhered to.Aim: The aim was to present a case of a patient who underwent sleeve gastrectomy for the treatment of ...

Hypokalemia has been observed in cases of the new SARS-CoV-2 infection. It has been suggested that hypokalemia may be a sensitive biomarker of disease severity and the requirement for invasive mechanical ventilation requirement in COVID-19 pneumonia. The aim was to describe the case of a patient with severe SARS-CoV-2 pneumonia who developed severe hypokalemia. A patient, male, aged 52, presented with fever and dry cough. He was found to be positive for the SARS-CoV-2 infectio...

Infection with the new SARS-CoV-2 or Covid-19 virus has a variable course. It may run as a mild disease or may cause severe pneumonia necessitating hospitalization. Vitamin D has immunostimulatory action and causes the release of substances necessary for combating an infection. Therefore, the relationship of vitamin D with the SARS-CoV-2 virus is under scientific evaluation. The aim was to measure vitamin D levels in a cohort of patients hospitalized with SARS-CoV-2 infection....

Introduction: Vitamin D is currently known for its effects on the bone and muscle systems as well as for its pleiotropic and antiproliferative effects. The relationship between vitamin D and diabetes mellitus is in the focus of scientific research. Vitamin D deficiency has been found to be associated with the development of diabetes mellitus type 1 as well as with poor glycemic control in diabetes mellitus type 2.Aim: The aim was to study the effect of v...