Endocrine Abstracts

Introduction: Various hematologic disorders have been reported in hypothyroidism. They are resulting from the effect of thyroid hormones regulating the hematopoiesis.Population and methodology: 100 patients with primary hypothyroidism unsubstituted received a thyroid balance (FT4, TSH us, and Ac anti-TPO cevicale ultrasound) and hematologic exploration (FNS determination of serum ferritin, TIBC). The blood test was completed according to the r...

Introduction: Cardiothyreosis (CT) is the most frequent and dangerous complication of hyperthyroidism (HT). It is defined as an association of HT with severe heart abnormalities such: rhythmic troubles, heart and/or coronary insufficiency, atrio-ventricular block, and arterial pulmonary hypertension.Our aim was to study its frequency, in Algerian population, analyze its profile and its response to radical treatment.Materials and me...

Introduction: Hypothyroidism is a frequent pathology responsible for a significant increase in cholesterol. It is caracterized by myocardial changes, increased risk of cardiovascular disease and more particularly coronary event performance.Aim: Assess cardiovascular risk factors in adults suffering from primary hypothyroidism.Materials and methods: This retrospective study included data from 50 patients (44 women and 6 men) adults ...

Introduction: Graves’ disease is rare but may be complicated by major eye signs of Graves’ series rarely causing paralysis of the optic nerve.Aim: Report cases of seven patients collected between 1982 and 2013 presenting Graves’ disease complicated by optical neuropathy.Observations: Men patients aged on average 44 years old (35–48), admitted for Graves’ disease complicated by ophthalmopathy with oculomotor...

The adrenal enzyme deficiency leads pseudopuberty in later diagnosis or in the absence of treatment. The existence of testicular enlargement in boys can be related to adrenal inclusion. We report six observations about this pathology: Two brothers of 2 and 12 years old with 11β-hydroxylase and four patients of three, five, height and ten years old with 21-hydroxylase deficiency. The reson of consultation was the development of the penis and pubic hair with a testiculary e...

The occurrence of Cushing’ syndrome in pregnancy is a rare entity due to hypogonadism. Its diagnosis and treatment are very difficult because pregnancy causes hormonal and physical changes which can lead to confusion. In addition, the therapeutic opties are limited because of reduced fetal risk. We rereport the observations of three patients who presented severe Cushing’ syndrome appeared in the first part of pregnancy. This is unkown despite a very evocative paintin...

Paraganglioma is a tumor developed in expenses of the sympathetic or parasympathetic nervous system. It is a rare pathology (prevalency 1 for 30 000). These are situated on the basis of skull, at the level of neck, in the thorax and the belly. Some paraganglioma are functional and secrete cathecolamines and others are diagnosed after surgery in the histological study of the operating piece. Through a retrospective study concerning height patients having paraganglioma extra sur...

Introduction: In the whole world normocalcemic hyperparathyroidism (NC HPT) is an emerging entity and a growing problem. This disease is characterized by high levels of intact parathyroid hormone with normal total or ionized serum calcium. Our aim is to analyze its clinical and biological profile and its etiologies.Subjects and methods: We have studied 18 subjects with NC HPT. They all had routine analyses, plasma calcium and phosphorous, and assessment ...

Introduction: Vitamin D (Vit D) is known for its action on bone metabolism. But recently more ubiquitous actions have been discovered. Vit D deficit is now considered as a world health problem because of it frequency and its consequences. Vit D deficiency seems to be involved in diabetes mellitus, and in autoimmune, neoplastic and cardio-metabolic diseases. The aim of our study was to analyze the incidence of cardio-metabolic diseases in a group of patients with vitamin D defi...

Introduction: Hyperparathyroidism (HPT) is a common disease prevailing in females (F). Male (M) forms are rare and their impact on the body is less studied than in females. Our aim is to see if male HPT is more or less aggressive than the female one.Subjects and methods: It is a retrospective study that took in account 62 HPT (46F, 16M) over a period of 7 years (2005–2012). All were questioned, examined, and had routine analyses, biological assessme...